成纤维细胞生长因子15(FGF15)活性蛋白
Active Fibroblast Growth Factor 15 (FGF15)
- 编号APL154Hu01
- 物种Homo sapiens (Human，人)相同的名称，不同的物种。
- 缓冲液成份20mM Tris, 150mM NaCl缓冲液（pH8.0, 含有1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose和Proclin300）
- 性状冻干粉
- 纯度> 90%
- 等电点-
- 应用Cell culture; Activity Assays.
- 下载英文说明书 中文说明书
- 规格10µg50µg200µg1mg5mg
- 价格¥ 1680¥ 4200¥ 8400¥ 25200¥ 63000
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产品包装(模拟)
产品包装(模拟)
通过ISO 9001、ISO 13485质量体系认证
活性实验
用法
Reconstitute in 20mM Tris, 150mM NaCl (PH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
储存
避免反复冻融。2-8°C不超过一个月，-80°C不超过12个月。
稳定性
热稳定性以损失率显示。损失率是由加速降解试验决定，具体方法如下：在37°C孵育48小时，没有显著的降解或者沉淀产生。保质期内，在适当的条件下存储，损失率低于5%。
增值服务
相关产品
| 编号 | 适用物种：Homo sapiens (Human，人) | 应用(仅供研究使用，不用于临床诊断！) |
| APL154Hu01 | 成纤维细胞生长因子15(FGF15)活性蛋白 | Cell culture; Activity Assays. |
参考文献
| 杂志 | 参考文献 |
| Endocrinology. | Naringenin Prevents Obesity, Hepatic Steatosis, and Glucose Intolerance in Male Mice Independent of Fibroblast Growth Factor 21[PubMed: 25774553] |
| Inflammatory Bowel Diseases | Alterations in Enterohepatic Fgf15 Signaling and Changes in Bile Acid Composition Depend on Localization of Murine Intestinal Inflammation[pubmed:27580383] |
| J Lipid Res. | Commensal bacteria at the crossroad between cholesterol homeostasis and chronic inflammation in atherosclerosis.[pubmed:28130274] |
| BMC Endocrine Disorders | The relationship between bile acid concentration, glucagon-like-peptide 1, fibroblast growth factor 15 and bile acid receptors in rats during progression of glucose intolerance[10.1186/s12902-017-0211-5] |
| Journal of Physiology and Biochemistry | The ileal FGF15/19 to hepatic FGFR4 axis regulates liver regeneration after partial hepatectomy in mice[Pubmed:29468415] |
| Developmental Cell | FGF15 Activates Hippo Signaling to Suppress Bile Acid Metabolism and Liver Tumorigenesis[Pubmed: 30745141] |
| Endocrinology | Interactions between the gravitostat and the fibroblast growth factor system for the regulation of body weight[] |
| Food & Function | Lactoferrin promotes bile acid metabolism and reduces hepatic cholesterol deposition by inhibiting the farnesoid X receptor (FXR)-mediated enterohepatic axis[Pubmed: 31626262] |
| Journal of Translational Medicine | Gut microbiota from coronary artery disease patients contributes to vascular dysfunction in mice by regulating bile acid metabolism and immune activation[Pubmed: 33036625] |
| Chin Med | Si-Wu-Tang ameliorates fibrotic liver injury via modulating intestinal microbiota and bile acid homeostasis[34736501] |
| Int J Biol Sci | Dynamics of the gut-liver axis in rats with varying fibrosis severity[Pubmed:35637968] |