淀粉样前体蛋白(APP)重组蛋白
Recombinant Amyloid Precursor Protein (APP)
AAA; ABeta; ABPP; AD1; APPI; CVAP; PN2; CTFgamma; Peptidase Nexin-II Alzheimer Disease; Peptidase Nexin-II; Amyloid Beta(A4)Precursor Protein
- 编号RPB020Hu01
- 物种Homo sapiens (Human，人)相同的名称，不同的物种。
- 来源原核表达
- 宿主E.coli
- 内毒素水平<1.0EU/µg(LAL法测定)
- 亚细胞定位细胞膜, 细胞核, 分泌, 细胞质
- 预测分子量54.2kDa
- 实际分子量54kDa(差异分析请参阅说明书)
- 片段与标签Asp672~Val711 with Two N-terminal Tags, His-tag and MBP-tag
- 缓冲液成份20mM Tris, 150mM NaCl缓冲液（pH8.0, 含有1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose和Proclin300）
- 性状冻干粉
- 纯度> 90%
- 等电点5.5
- 应用Positive Control; Immunogen; SDS-PAGE; WB.
如果需要有生物活性的蛋白，请参见活性蛋白。 - 下载英文说明书 中文说明书
- 规格10µg50µg200µg1mg5mg
- 价格¥ 1032¥ 2580¥ 5160¥ 15480¥ 38700
- 欲了解实际交易价格和更多情况，请与当地经销商联系!
产品包装(模拟)
产品包装(模拟)
Figure. SDS-PAGE
通过ISO 9001、ISO 13485质量体系认证
序列
用法
Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
储存
避免反复冻融。2-8°C不超过一个月，-80°C不超过12个月。
稳定性
热稳定性以损失率显示。损失率是由加速降解试验决定，具体方法如下：在37°C孵育48小时，没有显著的降解或者沉淀产生。保质期内，在适当的条件下存储，损失率低于5%。
增值服务
相关产品
| 编号 | 适用物种：Homo sapiens (Human，人) | 应用(仅供研究使用，不用于临床诊断！) |
| RPB020Hu02 | 淀粉样前体蛋白(APP)重组蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPB020Hu03 | 淀粉样前体蛋白(APP)重组蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPB020Hu01 | 淀粉样前体蛋白(APP)重组蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| PAB020Hu01 | 淀粉样前体蛋白(APP)多克隆抗体 | WB; IHC; ICC; IP. |
| PAB020Hu02 | 淀粉样前体蛋白(APP)多克隆抗体 | WB; IHC; ICC; IP. |
| PAB020Hu03 | 淀粉样前体蛋白(APP)多克隆抗体 | WB; IHC; ICC; IP. |
| MAB020Hu22 | 淀粉样前体蛋白(APP)单克隆抗体 | WB; IHC; ICC; IP. |
| MAB020Hu23 | 淀粉样前体蛋白(APP)单克隆抗体 | WB; IHC; ICC; IP. |
| WEB020Hu | 淀粉样前体蛋白(APP)检测试剂盒(酶联免疫吸附试验法,宽范围) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| SEB020Hu | 淀粉样前体蛋白(APP)检测试剂盒(酶联免疫吸附试验法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| SCB020Hu | 淀粉样前体蛋白(APP)检测试剂盒(化学发光免疫分析法) | Chemiluminescent immunoassay for Antigen Detection. |
| LMB020Hu | 淀粉样前体蛋白(APP)等多因子检测试剂盒(流式荧光发光法) | FLIA Kit for Antigen Detection. |
参考文献
| 杂志 | 参考文献 |
| Neurochemistry International | Bilobalide regulates soluble amyloid precursor protein release via phosphatidyl inositol 3 kinase-dependent pathway[ScienceDirect: S0197018611001641] |
| Neuroscience | Substitution of membrane cholesterol with β-sitosterol promotes nonamyloidogenic cleavage of endogenous amyloid precursor protein[Pubmed: 23707801] |
| OncoImmunology | PROOF COVER SHEET[] |
| 台湾农业研究 | (台灣農業研究67 (4): 355-364) 香菇柄水萃物改善糖尿病降低阿茲海默氏症罹病風險初探[] |
| Neurotoxicology | Involvement of hippocampal agmatine in β1-42 amyloid induced memory impairment, neuroinflammation and BDNF signaling disruption in mice[Pubmed: 32522471] |
| Metab Brain Dis | Probiotics ameliorates LPS induced neuroinflammation injury on Aβ 1–42, APP, γ-β secretase and BDNF levels in maternal gut microbiota and fetal …[Pubmed:35312928] |
| Exp Gerontol | The positive impact of 12 weeks of dance and balance training on the circulating amyloid precursor protein and serotonin concentration as well as physical and …[Pubmed:35217193] |