武汉云克隆科技股份有限公司

血小板反应蛋白解整合素金属肽酶4(ADAMTS4)多克隆抗体

Polyclonal Antibody to A Disintegrin And Metalloproteinase With Thrombospondin 4 (ADAMTS4)

ADMP-1; Aggrecanase-1

  • 血小板反应蛋白解整合素金属肽酶4(ADAMTS4)多克隆抗体产品包装(模拟)
  • 血小板反应蛋白解整合素金属肽酶4(ADAMTS4)多克隆抗体产品包装(模拟)
  • 血小板反应蛋白解整合素金属肽酶4(ADAMTS4)多克隆抗体Used in DAB staining on fromalin fixed paraffin-embedded Lung tissue
  • PAK204Hu01.jpgFigure. Western Blot; Sample: Recombinant ADAMTS4, Human.
  • Certificate通过ISO 9001、ISO 13485质量体系认证

特异性

该抗体是针对ADAMTS4的兔多克隆抗体。在免疫组织化学染色和免疫印迹实验中能识别ADAMTS4。

用法

Western blotting: 0.01-2µg/mL;
Immunohistochemistry: 5-20µg/mL;
Immunocytochemistry: 5-20µg/mL;
Optimal working dilutions must be determined by end user.

储存

经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。

稳定性

热稳定性以损失率显示。损失率是由加速降解试验决定，具体方法如下：在37°C孵育48小时，没有显著的降解或者沉淀产生。保质期内，在适当的条件下存储，损失率低于5%。

赠品

参考文献

杂志参考文献
Biomedicine & PharmacotherapyADAMTS4 level in patients with stable coronary artery disease and acute coronary syndromes[ScienceDirect: S0753332209002017]
PLoS ONEA Combinatorial Relative Mass Value Evaluation of Endogenous Bioactive Proteins in Three-Dimensional Cultured Nucleus Pulposus Cells of Herniated Intervertebral Discs: Identification of Potential Target Proteins for Gene Therapeutic Approaches[Plosone: Source]
Anadolu Kardiyol Derg.A novel association between TGFb1 and ADAMTS4 in coronary artery disease: A new potential mechanism in the progression of atherosclerosis and diabetes.[Pubmed:25592103]
Osteoarthritis and CartilageLack of anti-inflammatory and anti-catabolic effects on basal inflamed osteoarthritic chondrocytes or synoviocytes by adipose stem cell-conditioned medium[PubMed: 26521751]
Osteoarthritis and CartilageParathyroid hormone(1-34) exhibits more comprehensive effects than celecoxib in cartilage metabolism and maintaining subchondral bone micro-architecture in meniscectomized Cavia (Guinea pig )inea pigs[Pubmed:26802547]
Journal of Cellular and Molecular MedicineVIP and CRF reduce ADAMTS expression and function in osteoarthritis synovial fibroblasts[Pubmed:26818776]
Int Wound J.From varices to venous ulceration: the story of chronic venous disease described by metalloproteinases.[Pubmed:26991748]
The American journal of pathologyHealthy and Osteoarthritic Synovial Fibroblasts Produce a Disintegrin and Metalloproteinase with Thrombospondin Motifs 4, 5, 7, and 12: Induction by IL-1β and Fibronectin and Contribution to Cartilage Damage.[pubmed:27449198]
International Wound JournalFrom varices to venous ulceration: the story of chronic venous disease described by metalloproteinases[pubmed:26991748]
American Journal of Translational ResearchDiagnostic utility of fluorogenic peptide-conjugated Au nanoparticle probe corroborated by rabbit model of mild cartilage injury and panel of osteoarthritic …[Pubmed: 30210670]
Journal of Clinical MedicineThe Effects of TNF-α Inhibition on the Metabolism of Cartilage: Relationship between KS, HA, HAPLN1 and ADAMTS4, ADAMTS5, TOS and TGF-β1 Plasma …[Pubmed:35407621]