酸性神经鞘磷脂酶(ASM)多克隆抗体
Polyclonal Antibody to Acid Sphingomyelinase (ASM)
SMPD1; NPD; SMase; aSMase; Sphingomyelin Phosphodiesterase 1,Acid Lysosomal; Simply Sphingomyelinase
- 编号PAB360Hu01
- 物种Homo sapiens (Human，人)相同的名称，不同的物种。
- 来源多抗制备
- 宿主兔
- 效价-
- Ig类型IgG
- 纯化方式抗原特异性亲和纯化
- 标记物无标记物
- 免疫原RPB360Hu01-酸性神经鞘磷脂酶(ASM)重组蛋白
- 缓冲液成份磷酸盐缓冲液（pH7.4,含有0.02% NaN3和50%甘油）
- 性状液体
- 浓度0.5mg/mL
- 且适物种Mus musculus (Mouse，小鼠), Sus scrofa; Porcine (Pig，猪)
- 应用WB; IHC; ICC; IP.
如果抗体需用于流式细胞术，请参见流式抗体。 - 下载英文说明书 中文说明书
- 规格20µl100µl200µl1ml10ml
- 价格¥ 598¥ 1394¥ 1992¥ 4980¥ 19920
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产品包装(模拟)
产品包装(模拟)
DAB staining on IHC-P; Samples: Human Cerebrum Tissue; Primary Ab: 20μg/ml Rabbit Anti-Human ASM Antibody Second Ab: 2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: SAA544Rb19)
Figure. Western Blot; Sample: Recombinant ASM, Human.
Figure. Western Blot; Sample: Mouse Brain Tissue.
通过ISO 9001、ISO 13485质量体系认证
特异性
该抗体是针对ASM的兔多克隆抗体。在免疫组织化学染色和免疫印迹实验中能识别ASM。
用法
Western blotting: 0.01-2µg/mL;
Immunohistochemistry: 5-20µg/mL;
Immunocytochemistry: 5-20µg/mL;
Optimal working dilutions must be determined by end user.
储存
经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。
稳定性
热稳定性以损失率显示。损失率是由加速降解试验决定，具体方法如下：在37°C孵育48小时，没有显著的降解或者沉淀产生。保质期内，在适当的条件下存储，损失率低于5%。
赠品
增值服务
相关产品
| 编号 | 适用物种：Homo sapiens (Human，人) | 应用(仅供研究使用，不用于临床诊断！) |
| EPB360Hu61 | 酸性神经鞘磷脂酶(ASM)真核蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPB360Hu01 | 酸性神经鞘磷脂酶(ASM)重组蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| APB360Hu61 | 酸性神经鞘磷脂酶(ASM)活性蛋白 | Cell culture; Activity Assays. |
| PAB360Hu01 | 酸性神经鞘磷脂酶(ASM)多克隆抗体 | WB; IHC; ICC; IP. |
| MAB360Hu22 | 酸性神经鞘磷脂酶(ASM)单克隆抗体 | WB; IHC; ICC; IP. |
| SEB360Hu | 酸性神经鞘磷脂酶(ASM)检测试剂盒(酶联免疫吸附试验法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| MEB360Hu | 酸性神经鞘磷脂酶(ASM)检测试剂盒(酶联免疫吸附试验法,小样本) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| LMB360Hu | 酸性神经鞘磷脂酶(ASM)等多因子检测试剂盒(流式荧光发光法) | FLIA Kit for Antigen Detection. |
参考文献
| 杂志 | 参考文献 |
| Blood.? | Acid sphingomyelinase is activated in sickle cell erythrocytes and contributes to inflammatory microparticle generation in SCD[Pubmed:25075126] |
| Journal of Clinical Lipidology | Increase in acid sphingomyelinase level in human retinal endothelial cells and CD34+ circulating angiogenic cells isolated from diabetic individuals is associated with dysfunctional retinal vasculature and vascular repair process in diabetes[10.1016/j.jacl.2017.03.007] |
| Diabetes & metabolism | Fenofibrate decreases plasma ceramide in type 2 diabetes patients: A novel marker of CVD?[pubmed:28499696] |
| INFLAMMATION | Acid Sphingomyelinase and Acid ¦Â-Glucosidase 1 Exert Opposite Effects on Interleukin-1¦Â-Induced Interleukin 6 Production in Rheumatoid Arthritis Fibroblast-Like Synoviocytes[33665756] |
| Indian J Ophthalmol | Evaluation of sphingolipid metabolism on diabetic retinopathy[34708809] |