颗粒酶B(GZMB)单克隆抗体
Monoclonal Antibody to Granzyme B (GZMB)
GZM-B; HLP; CTLA1; CCPI; CGL1; CSP-B; CSPB; CTSGL1; SECT; Granzyme 2; Cytotoxic T-Lymphocyte-Associated Serine Esterase 1; Fragmentin 2; Cytotoxic Serine Protease B
- 编号MAA600Hu22
- 物种Homo sapiens (Human，人)相同的名称，不同的物种。
- 来源单抗制备
- 宿主小鼠
- 效价(克隆号)D2
- Ig亚型 IgG2b Kappa
- 纯化方式蛋白A + 蛋白G亲和纯化
- 标记物无标记物
- 免疫原RPA600Hu01-颗粒酶B(GZMB)重组蛋白
- 缓冲液成份0.01M 磷酸盐缓冲液（pH7.4，containing 0.05% Proclin-300，50% glycerol）
- 性状液体
- 浓度1mg/mL
- 且适物种-
- 应用WB
如果抗体需用于流式细胞术，请参见流式抗体。 - 下载英文说明书 中文说明书
- 规格20µl100µl200µl1ml10ml
- 价格¥ 605¥ 1411¥ 2016¥ 5040¥ 20160
- 欲了解实际交易价格和更多情况，请与当地经销商联系!
产品包装(模拟)
产品包装(模拟)
IHC图
Western Blot; Sample: Human PBMC cell lysate Primary Ab: 0.04µg/ml Mouse Anti-Human GZMB Antibody Second Ab: 0.2µg/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody (Catalog: SAA544Mu19)
通过ISO 9001、ISO 13485质量体系认证
特异性
该抗体是针对GZMB的小鼠单克隆抗体。在免疫组织化学染色和免疫印迹实验中能识别GZMB。
用法
Western blotting: 0.01-2µg/mL;
Optimal working dilutions must be determined by end user.
储存
经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。
稳定性
热稳定性以损失率显示。损失率是由加速降解试验决定，具体方法如下：在37°C孵育48小时，没有显著的降解或者沉淀产生。保质期内，在适当的条件下存储，损失率低于5%。
赠品
增值服务
相关产品
| 编号 | 适用物种：Homo sapiens (Human，人) | 应用(仅供研究使用，不用于临床诊断！) |
| RPA600Hu01 | 颗粒酶B(GZMB)重组蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| PAA600Hu01 | 颗粒酶B(GZMB)多克隆抗体 | WB; IHC |
| MAA600Hu22 | 颗粒酶B(GZMB)单克隆抗体 | WB |
| MAA600Hu21 | 颗粒酶B(GZMB)单克隆抗体 | WB |
| SEA600Hu | 颗粒酶B(GZMB)检测试剂盒(酶联免疫吸附试验法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| LMA600Hu | 颗粒酶B(GZMB)等多因子检测试剂盒(流式荧光发光法) | FLIA Kit for Antigen Detection. |
参考文献
| 杂志 | 参考文献 |
| International Journal of Cancer | Effective immunotherapy of rat glioblastoma with prolonged intratumoral delivery of exogenous heat shock protein Hsp70[Pubmed:24691976] |
| Biol Pharm Bull. | Z-100, an Immunomodulatory Extract of Mycobacterium tuberculosis Strain Aoyama B, Prevents Spontaneous Lymphatic Metastasis of B16-BL6 Melanoma[Pubmed:24818259] |
| Journal of Dermatological Science | Relationships among plasma granzyme B level, pruritus and dermatitis in patients with atopicdermatitis.[pubmed:27686401] |
| Oncotarget | Tumor-derived granzyme B-expressing neutrophils acquire antitumor potential after lipid A treatment[Pubmed:29983866] |
| Theranostics | A novel Granzyme B nanoparticle delivery system simulates immune cell functions for suppression of solid tumors[Pubmed: 31695790] |
| Am J Transl Res | Combined treatment with epigenetic agents enhances anti-tumor activity of T cells by upregulating the ACRBP expression in hepatocellular carcinoma[34377237] |