武汉云克隆科技股份有限公司

分泌型卷曲相关蛋白5(SFRP5)多克隆抗体

Polyclonal Antibody to Secreted Frizzled Related Protein 5 (SFRP5)

SARP3; Secreted Apoptosis Related Protein 3; Frizzled-related protein 1b

  • 分泌型卷曲相关蛋白5(SFRP5)多克隆抗体产品包装(模拟)
  • 分泌型卷曲相关蛋白5(SFRP5)多克隆抗体产品包装(模拟)
  • 分泌型卷曲相关蛋白5(SFRP5)多克隆抗体IHC图
  • PAC842Mu01.jpgFigure. Western Blot; Sample: Recombinant SFRP5, Mouse.
  • 分泌型卷曲相关蛋白5(SFRP5)多克隆抗体Western Blot; Sample: Mouse Heart lysate
    Primary Ab: 0.2µg/ml Rabbit Anti-Mouse SFRP5 Antibody
    Second Ab: 0.2μg/ml HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
    (Catalog: SAA544Rb19)
  • Certificate通过ISO 9001、ISO 13485质量体系认证

特异性

该抗体是针对SFRP5的兔多克隆抗体。在免疫组织化学染色和免疫印迹实验中能识别SFRP5。

用法

Western blotting: 0.5-2µg/mL
Immunohistochemistry: 5-20µg/mL
Immunocytochemistry: 5-20µg/mL
Optimal working dilutions must be determined by end user.

储存

经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。

稳定性

热稳定性以损失率显示。损失率是由加速降解试验决定，具体方法如下：在37°C孵育48小时，没有显著的降解或者沉淀产生。保质期内，在适当的条件下存储，损失率低于5%。

赠品

相关产品

编号适用物种：Mus musculus (Mouse，小鼠)应用(仅供研究使用，不用于临床诊断！)
RPC842Mu01分泌型卷曲相关蛋白5(SFRP5)重组蛋白Positive Control; Immunogen; SDS-PAGE; WB.
RPC842Mu02分泌型卷曲相关蛋白5(SFRP5)重组蛋白Positive Control; Immunogen; SDS-PAGE; WB.
PAC842Mu01分泌型卷曲相关蛋白5(SFRP5)多克隆抗体WB; IHC; ICC; IP.
PAC842Mu02分泌型卷曲相关蛋白5(SFRP5)多克隆抗体WB; IHC; ICC; IP.
LAC842Mu71分泌型卷曲相关蛋白5(SFRP5)多克隆抗体(生物素标记)WB; IHC; ICC.
SEC842Mu分泌型卷曲相关蛋白5(SFRP5)检测试剂盒(酶联免疫吸附试验法)Enzyme-linked immunosorbent assay for Antigen Detection.
LMC842Mu分泌型卷曲相关蛋白5(SFRP5)等多因子检测试剂盒(流式荧光发光法)FLIA Kit for Antigen Detection.

参考文献

杂志参考文献
Diabetes Research and Clinical PracticePlasma SFRP5 levels are decreased in Chinese subjects with obesity and type 2 diabetes and negatively correlated with parameters of insulin resistance[PubMed: 23290274]
European Journal of Clinical InvestigationSfrp5 correlates with insulin resistance and oxidative stress[PubMed: 23398169]
Pediatric ResearchBalanced duo of anti-inflammatory SFRP5 and proinflammatory WNT5A in children[Pubmed: 24603290]
Clin Endocrinol (Oxf).SFRP5 correlates with obesity and metabolic syndrome and increases after weight loss in children[Pubmed: 24330025]
The Journal of Clinical Endocrinology & MetabolismCirculating Sfrp5 is a signature of obesity-related metabolic disorders and is regulated by glucose and liraglutide in humans[Pubmed: 23185036]
AtherosclerosisLow serum level of secreted frizzled-related protein 5, an anti-inflammatory adipokine, is associated with coronary artery disease[Pubmed: 24530778]
PLoS One.Identification of adipokine clusters related to parameters of fat mass, insulin sensitivity and inflammation[Pubmed:Pmc4072672]
J Clin Endocrinol Metab.Activation of noncanonical Wnt signaling through WNT5A in visceral adipose tissue of obese subjects is related to inflammation[Pubmed:24840810]
Oncology LettersSerum secreted frizzled?related protein 5 levels differentially decrease in patients with hepatitis B virus?associated chronic infection and hepatocellular carcinoma[Pubmed:25120720]
Diabetes Metab Res Rev.Circulating SFRP5 levels are elevated in drug‐na?ve recently diagnosed type 2 diabetic patients as compared with prediabetic subjects and controls[Pubmed:25139699]
Clinical & Experimental ImmunologyThe wingless-related integration site-5a/secreted frizzled-related protein-6 system is dysregulated in human sepsis[Pubmed:25382802]
Diabetes Metab Res RevCirculating SFRP5 levels are elevated in drug-na[PubMed: 25139699]
J Matern Fetal Neonatal MedPrediction of gestational diabetes mellitus by first trimester serum secreted frizzle-related protein-5 levels[PubMed: 26100762]
Eur J Clin InvestSfrp5 associates with beta-cell function in humans[Pubmed:27019073]
Osteoporosis InternationalBone marrow sFRP5 level is negatively associated with bone formation markers[pubmed:27986984]
Diabetes/Metabolism Research and ReviewsPlasma Sfrp5 levels correlate with determinants of the metabolic syndrome in Chinese adults[pubmed:28303637]
Cardiovascular DiabetologyInverse associations between serum levels of secreted frizzled-related protein-5 (SFRP5) and multiple cardiometabolic risk factors: KORA F4 study[pubmed:28851362]
Arteriosclerosis, Thrombosis, and Vascular Biology Effect of SFRP5 (Secreted Frizzled–Related Protein 5) on the WNT5A (Wingless-Type Family Member 5A)-Induced Endothelial Dysfunction and Its Relevance With …[Pubmed:29674475]
ObesityLongitudinal Increases in Adiposity Contribute to Worsening Adipokine Profile over Time in Mexican Americans[Pubmed:29427376]
J Bas Res Med SciDecreased level of the anti-inflammatory adipokines, secreted frizzled-related protein 5 and adiponectin, in high cholesterol diet-induced atherosclerotic rats[article-1-352-en.pdf]
Molecular Biology ReportsThe effect of serum and follicular fluid secreted frizzle-related protein-5 on in vitro fertilization outcomes in patients with polycystic ovary syndrome[Pubmed: 30194556]
Macrophage LRP1 promotes diet-induced hepatic inflammation and metabolic dysfunction by modulating Wnt signaling[]
British Journal Of NutritionA diet high in sugar-sweetened beverage and low in fruits and vegetables is associated with adiposity and a pro-inflammatory adipokine profile[Pubmed: 30375290]
J Clin Endocrinol MetabRole of wnt5a in Metabolic Inflammation in Humans[Pubmed: 30137542]
Frontiers in EndocrinologyAssociation of Adipocytokines With Carotid Intima Media Thickness and Arterial Stiffness in Obstructive Sleep Apnea Patients[Pubmed: 32300333]
CLINICAL BIOCHEMISTRYSfrp5/Wnt5a and Leptin/adiponectin levels in the serum and the periarterial adipose tissue of patients with peripheral arterial occlusive disease[Pubmed: 33188773]
Sao Paulo Medical JournalAssociation of serum levels of secreted frizzled-related protein 5 and Wnt member 5a with glomerular filtration rate in patients with type 2 diabetes mellitus and …[Pubmed: 32491086]
Kidney Blood Press ResSecreted Frizzled-Related Protein 5 Ameliorates Vascular Calcification in a Rat Model of Chronic Kidney Disease through the Wnt/β-Catenin Pathway[34469882]
CytokineAssociation of serum uromodulin with adipokines in dependence of type 2 diabetes[34920231]
PLoS OneAssociation of circulating MR-proADM with all-cause and cardiovascular mortality in the general population: Results from the KORA F4 cohort study[Pubmed:34990470]
JMIR Res ProtocInvestigating New Sensory Methods Related to Taste Sensitivity, Preferences, and Diet of Mother-Infant Pairs and Their Relationship With Body Composition …[Pubmed:35475790]
DiabetologyEarly Pregnancy Serum Concentration of Secreted Frizzled-Related Protein 4, Secreted Frizzled-Related Protein 5, and Chemerin in Obese Women Who Develop …[]