武汉云克隆科技股份有限公司

沉默调节蛋白1(SIRT1)单克隆抗体

Monoclonal Antibody to Sirtuin 1 (SIRT1)

SIR2L1; Silent Mating Type Information Regulation 2 Homolog 1; NAD-Dependent Deacetylase Sirtuin-1; SIR2-like protein 1; SirtT1 75 kDa fragment

  • 沉默调节蛋白1(SIRT1)单克隆抗体产品包装(模拟)
  • 沉默调节蛋白1(SIRT1)单克隆抗体产品包装(模拟)
  • MAE912Hu22.jpgFigure. Western Blot; Sample: Recombinant SIRT1, Human.
  • Certificate通过ISO 9001、ISO 13485质量体系认证

特异性

该抗体是针对SIRT1的小鼠单克隆抗体。在免疫组织化学染色和免疫印迹实验中能识别SIRT1。

用法

Western blotting: 0.01-2µg/mL;
Immunohistochemistry: 5-20µg/mL;
Immunocytochemistry: 5-20µg/mL;
Optimal working dilutions must be determined by end user.

储存

经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。

稳定性

热稳定性以损失率显示。损失率是由加速降解试验决定，具体方法如下：在37°C孵育48小时，没有显著的降解或者沉淀产生。保质期内，在适当的条件下存储，损失率低于5%。

赠品

相关产品

编号适用物种：Homo sapiens (Human，人)应用(仅供研究使用，不用于临床诊断！)
RPE912Hu01沉默调节蛋白1(SIRT1)重组蛋白Positive Control; Immunogen; SDS-PAGE; WB.
PAE912Hu01沉默调节蛋白1(SIRT1)多克隆抗体WB
LAE912Hu81沉默调节蛋白1(SIRT1)多克隆抗体(异硫氰酸荧光素标记)WB; IHC; ICC; IF.
LAE912Hu71沉默调节蛋白1(SIRT1)多克隆抗体(生物素标记)WB; IHC; ICC.
MAE912Hu22沉默调节蛋白1(SIRT1)单克隆抗体WB; IHC; ICC; IP.
MAE912Hu23沉默调节蛋白1(SIRT1)单克隆抗体WB; IHC; ICC; IP.
MAE912Hu21沉默调节蛋白1(SIRT1)单克隆抗体WB; IHC; ICC; IP.
SEE912Hu沉默调节蛋白1(SIRT1)检测试剂盒(酶联免疫吸附试验法)Enzyme-linked immunosorbent assay for Antigen Detection.
LME912Hu沉默调节蛋白1(SIRT1)等多因子检测试剂盒(流式荧光发光法)FLIA Kit for Antigen Detection.
PSE912Hu01沉默调节蛋白1(SIRT1)抗体对ELISA; CLIA; ELISPOT; Luminex; Immunochromatography and other Immunoassays.
KSE912Hu01沉默调节蛋白1(SIRT1)检测试剂盒DIY材料(酶联免疫吸附试验法)Main materials for "Do It (ELISA Kit) Yourself".

参考文献

杂志参考文献
PLoS One.SIRT1 Gene Polymorphisms Affect the Protein Expression in Cardiovascular Diseases[Plos: Source]
PLOS ONEA Novel Role for SIRT-1 in L-Arginine Protection against STZ Induced Myocardial Fibrosis in Rats[Pubmed:25501750]
Journal of Alzheimer's DiseaseSerum miR-206 and miR-132 as Potential Circulating Biomarkers for Mild Cognitive Impairment[Pubmed:25589731]
RespirologyIncreases in peripheral SIRT1: A new biological characteristic of asthma[PubMed: 26040995]
PLOS ONEA Remarkable Age-Related Increase in SIRT1 Protein Expression against Oxidative Stress in Elderly:[PubMed: 25785999]
EndocrineChanges of serum Mir-217 and the correlation with the severity in type 2 diabetes patients with different stages of diabetic kidney disease.[pubmed:27522360]
Naunyn Schmiedebergs Arch PharmacolThe potential curative effect of rebamipide in hepatic ischemia/reperfusion injury[pubmed:28361247]
 International journal of cardiologyA sirtuin 1/MMP2 prognostic index for myocardial infarction in patients with advanced coronary artery disease[pubmed:28043667]
International Journal of CardiologySerum concentrations and gene expression of sirtuin 1 in healthy and slightly overweight subjects after caloric restriction or resveratrol supplementation: A randomized trial[pubmed:28029409]
Hepatology InternationalAssociation of SIRT1 gene polymorphism and its expression for the risk of alcoholic fatty liver disease in the Han population[pubmed:29189974]
Toxicology and Applied PharmacologySildenafil protects against bile duct ligation induced hepaticfibrosis in rats: Potential role for silent information regulator 1 (SIRT1)[pubmed:28974454]
Chemico-biological InteractionsMagnolol protects pancreatic β-cells against methylglyoxal-induced cellular dysfunction[pubmed:28919305]
NutrientsGene Expression of Sirtuin-1 and Endogenous Secretory Receptor for Advanced Glycation End Products in Healthy and Slightly Overweight Subjects after …[Pubmed:30037068]
Experimental GerontologySpecific alterations in the circulating levels of the SIRT1, TLR4, and IL7 proteins in patients with dementia[Pubmed:30071285]
Kidney and Blood Pressure ResearchThe Kidney Specific Protein myo-Inositol Oxygenase, a Potential Biomarker for Diabetic Nephropathy[Pubmed: 30504713]
Journal of International Medical ResearchSerum and follicular fluid levels of sirtuin 1, sirtuin 6, and resveratrol in women undergoing fertilization: an observational, clinical study[Pubmed: 30556451]
BioMed Research InternationalCentella asiatica Prevents Increase of Hippocampal Tumor Necrosis Factor-Independently of Its Effect on Brain-Derived Neurotrophic Factor in Rat Model of Chronic …[]
学位论文Influência do tratamento da doença periodontal na sirtuína 1 e na lectina ligadora de manose em indivíduos com doença arterial coronária[]
Journal of Physics D: Applied PhysicsPremature Myocardial Infarction: Genetic Variations in SIRT1 Affect Disease Susceptibility[]
Journal of Geriatric OncologySerum biomarkers for predicting overall survival and early mortality in older patients with metastatic solid tumors[Pubmed: 30952517]
Biomed Research InternationalPrevents Increase of Hippocampal Tumor Necrosis Factor-α Independently of Its Effect on Brain-Derived Neurotrophic Factor in Rat Model of …[Pubmed: 30956976]
Journal of Diabetes and its ComplicationsVasohibin-1 in T2DM with different UACR[]
Clinical Interventions in AgingThe Serum Concentration of Anti-Aging Proteins, Sirtuin1 and αKlotho in Patients with End-Stage Kidney Disease on Maintenance Hemodialysis[Pubmed: 32214805]
Compr PsychiatryCrocin alleviates schizophrenia-like symptoms in rats by upregulating silent information regulator-1 and brain derived neurotrophic factor[Pubmed: 33045669]
Сибирский федеральный университетВлияние гречневой крупы на сиртуиновую активность у подопытных животных в эксперименте[]
Journal of Cereal ScienceDietary buckwheat enhances sirtuin1 without calorie restriction[]
Clin Interv AgingMolecular Changes in Circulating microRNAs' Expression and Oxidative Stress in Adults with Mild Cognitive Impairment: A Biochemical and Molecular Study[33447019]
AntioxidantsThe Effect of Repeated Whole-Body Cryotherapy on Sirt1 and Sirt3 Concentrations and Oxidative Status in Older and Young Men Performing Different Levels of?¡­[33396247]
Int Urol NephrolEvaluation of sirtuin 1 (SIRT1) levels in autosomal dominant polycystic kidney disease[33864594]
Neurochem IntDimethyl fumarate abridged tauo-/amyloidopathy in a D-Galactose/ovariectomy-induced Alzheimer's-like disease: Modulation of AMPK/SIRT-1, AKT/CREB/BDNF, AKT ¡­[34052296]
Toxicol Appl PharmacolPrasugrel anti-ischemic effect in rats: Modulation of hippocampal SUMO2/3-IкBα/Ubc9 and SIRT-1/miR-22 trajectories[34174262]
Food ChemBuckwheat-enriched diet alleviates bisphenol A mediated oxidative stress via modulation of sirtuin 1 and antioxidant status in experimental rats[34763933]
Life SciNovel mechanistic insights towards the repositioning of alogliptin in Parkinson's disease[34774622]
Int J Mol SciIntralesional Infiltrations of Arteriosclerotic Tissue Cells-Free Filtrate Reproduce Vascular Pathology in Healthy Recipient Rats[Pubmed:35163435]
J Clin MedEffects of Coffee on Sirtuin-1, Homocysteine, and Cholesterol of Healthy Adults: Does the Coffee Powder Matter?[Pubmed:35683374]
Cell & BioscienceOGT Protects Skeletal Muscle From Damage Through SIRT1 O-GlcNAcylation During Cold Stress[]