武汉云克隆科技股份有限公司

Toll样受体4(TLR4)多克隆抗体

Polyclonal Antibody to Toll Like Receptor 4 (TLR4)

CD284; TOLL; HToll

  • Toll样受体4(TLR4)多克隆抗体产品包装(模拟)
  • Toll样受体4(TLR4)多克隆抗体产品包装(模拟)
  • Certificate通过ISO 9001、ISO 13485质量体系认证

特异性

该抗体是针对TLR4的兔多克隆抗体。在免疫组织化学染色和免疫印迹实验中能识别TLR4。

用法

免疫印迹：0.2-2µg/mL;1:250-2500
免疫组织化学：5-20µg/mL;1:25-100
免疫细胞化学：5-20µg/mL;1:25-100
最佳稀释倍数最终由用户决定。

储存

经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。

稳定性

热稳定性以损失率显示。损失率是由加速降解试验决定，具体方法如下：在37°C孵育48小时，没有显著的降解或者沉淀产生。保质期内，在适当的条件下存储，损失率低于5%。

赠品

相关产品

编号适用物种：Bos taurus; Bovine (Cattle，牛)应用(仅供研究使用，不用于临床诊断！)
RPA753Bo01Toll样受体4(TLR4)重组蛋白Positive Control; Immunogen; SDS-PAGE; WB.
PAA753Bo01Toll样受体4(TLR4)多克隆抗体WB; IHC; ICC; IP.
MAA753Bo21Toll样受体4(TLR4)单克隆抗体WB; IHC; ICC; IP.
SEA753BoToll样受体4(TLR4)检测试剂盒(酶联免疫吸附试验法)Enzyme-linked immunosorbent assay for Antigen Detection.
LMA753BoToll样受体4(TLR4)等多因子检测试剂盒(流式荧光发光法)FLIA Kit for Antigen Detection.

参考文献

杂志参考文献
Chinese Medical JournalExpression of soluble Toll-like receptors in pleural effusions[CMJ: 2010823483999506297]
Journal of Maternal-Fetal and Neonatal MedicineAmniotic fluid soluble Toll-like receptor 4 in pregnancies complicated by preterm prelabor rupture of the membranes[Informa: 14767058.2011.626821]
PLoS OneBaicalein Reduces Airway Injury in Allergen and IL-13 Induced Airway Inflammation[PubMed: PMC3639905]
Clin Res Hepatol Gastroenterol.The association between precancerous gastric lesions and serum pepsinogens, serum gastrin, vascular endothelial growth factor, serum interleukin-1 Beta, serum toll-like receptor-4 levels and Helicobacter pylori Cag A status[Pubmed: 23137754]
Journal of Clinical MicrobiologyToll-Like Receptor 2 in Serum: a Potential Diagnostic Marker of Prosthetic Joint Infection?[Pubmed: 24478497]
Surgical EndoscopyCO2 pneumoperitoneum increases secretory IgA levels in the gut compared with laparotomy in an experimental animal model.[Pubmed: 24442682]
Experimental and therapeutic medicineSoluble toll-like receptor 4 reversed attenuating effect of Chinese herbal Xiao-Qing-Long-Tang on allergen induced nerve growth factor and thymic stromal lymphopoietin[Pubmed: 24223644]
Free Radical Biology and MedicineInvolvement of nitric oxide with activation of Toll-like receptor 4 signaling in mice with dextran sodium sulfate-induced colitis[Pubmed:24992835]
Respiratory Virology and Immunogenicity Advances in Experimental Medicine and BiologyCytokines and Toll-Like Receptors in the Immune Response to Influenza Vaccination[Pubmed:25248345]
Molecular and Cellular BiochemistryBeta-arrestin-2 negatively modulates inflammation response in mouse chondrocytes induced by 4-mer hyaluronan oligosaccharide[Pubmed:25318610]
Journal of Ginseng ResearchEffects of Korean Red Ginseng (Panax ginseng), urushiol (Rhus vernicifera Stokes), and probiotics (Lactobacillus rhamnosus R0011 and Lactobacillus acidophilus R0052) on the gut–liver axis of alcoholic liver disease[Pubmed:25378990]
BMC ImmunologyThe discriminative capacity of soluble Toll-like receptor (sTLR)2 and sTLR4 in inflammatory diseases[Pubmed:25406630]
Gastroenterology Research and PracticeProcoagulatory State in Inflammatory Bowel Diseases Is Promoted by Impaired Intestinal Barrier Function[Pubmed:25767508]
Eur J Gastroenterol HepatolEfficacy of rifaximin on circulating endotoxins and cytokines in patients with nonalcoholic fatty liver disease[PubMed: 26043290]
Pathol Biol (Paris)Cathelicidin related antimicrobial peptide, laminin, Toll-like receptors and chemokines levels in experimental hypersensitivity pneumonitis in mice[PubMed: 25834936]
Journal of Food Science Effects of Hyriopsis cumingii Polysaccharides on Mice Immunologic Receptor, Transcription Factor, and Cytokine[Pubmed:27061742]
Plos OneSoluble Toll-Like Receptors 2 and 4 in Cerebrospinal Fluid of Patients with Acute Hydrocephalus followingAneurysmal Subarachnoid Haemorrhage.[Pubmed:27223696]
Open Forum Infect DisThe Effect of Rosuvastatin on Markers of Immune Activation in Treatment-Naive Human Immunodeficiency Virus-Patients[Pubmed:26835476]
Animal Feed Science and TechnologyImpact of Saccharomyces cerevisiae fermentation product and subacute ruminal acidosis on production, inflammation, and fermentation in the rumen and hindCavia (Guinea pig )t of dairy cows[science:S0377840115300493]
european journal of pharmacologyGarlic active constituent s-allyl cysteine protects against lipopolysaccharide-induced cognitive deficits in the rat: Possible involved mechanisms.[pubmed:27915041]
european journal of pharmacologyS-allyl cysteine ameliorates cognitive deficits in streptozotocin-diabetic rats via suppression of oxidative stress, inflammation, and acetylcholinesterase.[pubmed:27887948]
Psychopharmacology (Berl)Ellagic acid ameliorates learning and memory deficits in a rat model of Alzheimer's disease: an exploration of underlying mechanisms.[pubmed:28303372]
ЭНИ Забайкальский медицинский вестникНОСИТЕЛЬСТВО ПОЛИМОРФИЗМА Thr399Ile и Asp299Gly ГЕНА TLR4 И УРОВЕНЬ TLR4 В ОПУХОЛЕВОЙ ТКАНИ У БОЛЬНЫХ ПРОЛИФЕРАТИВНЫМИ ЗАБОЛЕВАНИЯМИ МОЛОЧНОЙ ЖЕЛЕЗЫ[8.pdf]
biomedicine & pharmacotherapyAcetyl-l-carnitine protects dopaminergic nigrostriatal pathway in 6-hydroxydopamine-induced model of Parkinson's disease in the rat.[pubmed:28199883]
Journal For NeurovirologySoluble TLR2 and 4 concentrations in cerebrospinal fluid in HIV/SIV-relatedneuropathological conditions.[pubmed:27882497]
Acta OrthopaedicaToll-like receptors and their soluble forms differ in the knee and thumb basal osteoarthritic joints[pubmed:28093922]
Environmental Toxicology and PharmacologyAmeliorative potential of linagliptin and/or calcipotriol on bleomycin-induced lung fibrosis: In vivo and in vitro study[pubmed:28192751]
InflammationToll-Like Receptor 4 Inhibition Improves Oxidative Stress and Mitochondrial Health in Isoproterenol-Induced Cardiac Hypertrophy in Rats[pubmed:28690610]
Comparative Immunology, Microbiology and Infectious DiseasesProbiotic Lactobacillus acidophilus bacteria or synthetic TLR2 agonist boost the growth of chicken embryo intestinal organoids in cultures comprising epithelial cells and myofibroblasts[DOI: 10.1016/j.cimid.2017.06.002]
Comparative Immunology, Microbiology and Infectious DiseasesProbiotic Lactobacillus acidophilus bacteria or synthetic TLR2 agonist boost the growth of chicken embryo intestinal organoids in cultures comprising epithelial cells and myofibroblasts[10.1016/j.cimid.2017.06.002]
Microbial PathogenesisProtective effects of sinomenine against LPS-induced inflammation in piglets.[pubmed:28757275]
CytokineSoy isoflavone genistein attenuates lipopolysaccharide-induced cognitive impairments in the rat via exerting anti-oxidative and anti-inflammatory effects[pubmed:29102164]
Biomedicine & pharmacotherapyBerberine ameliorates intrahippocampal kainate-induced status epilepticus and consequent epileptogenic process in the rat: Underlying mechanisms[pubmed:28061403]
Frontiers in ImmunologyThe soluble Form of Toll-like receptor 2 is elevated in serum of Multiple sclerosis Patients: a novel Potential Disease Biomarker[Pubmed:29593720]
Experimental GerontologySpecific alterations in the circulating levels of the SIRT1, TLR4, and IL7 proteins in patients with dementia[Pubmed:30071285]
Neurotoxicity ResearchProtective Effects of Fibroblast Growth Factor 21 Against Amyloid-Beta-Induced Toxicity in SH-SY5Y Cells[Pubmed:29869772]
European Journal of PharmacologyRutin, a quercetin glycoside, alleviates acute endotoxemic kidney injury in C57BL/6 mice via suppression of inflammation and up-regulation of antioxidants and SIRT1[Pubmed:29920283]
Environmental Toxicology and PharmacologyCrocin reverses unilateral renal ischemia reperfusion injury-induced augmentation of oxidative stress and toll like receptor-4 activity[Pubmed:29625388]
Physiology & Behavior Linagliptin potentiates the effect of l-dopa on the behavioural, biochemical and immunohistochemical changes in experimentally-induced Parkinsonism: Role of toll …[Pubmed:29410018]
International Journal of Gynecology & ObstetricsIncreased serum levels of high mobility group protein B1 and calprotectin in pre‐eclampsia[Pubmed:29569400]
Journal of Maternal-Fetal & Neonatal MedicineIncreased TLR4 and TREM-1 expression on monocytes and neutrophils in preterm birth: further evidence of a proinflammatory state[Pubmed:29534643]
ТLR4-РІВНІ У ХВОРИХ НА ПОДАГРУ: ЗВ'ЯЗОК З АКТИВНІСТЮ ЗАХВОРЮВАННЯ[:]
Journal of Medical VirologyCombined effect of anti‐high‐mobility group box‐1 monoclonal antibody and peramivir against influenza A virus‐induced pneumonia in mice[Pubmed: 30281823]
Metabolic Brain DiseaseBerberine ameliorates lipopolysaccharide-induced learning and memory deficit in the rat: insights into underlying molecular mechanisms[Pubmed: 30456649]
Experimental and Therapeutic MedicineThe HMGB1‑RAGE/TLR‑TNF‑α signaling pathway may contribute to kidney injury induced by hypoxia[]
Immunopharmacology and immunotoxicologyProtective effect of sesamin in lipopolysaccharide-induced mouse model of acute kidney injury via attenuation of oxidative stress, inflammation, and apoptosis[Pubmed: 30488751]
International ImmunopharmacologyS-allyl cysteine protects against lipopolysaccharide-induced acute kidney injury in the C57BL/6 mouse strain: Involvement of oxidative stress and inflammation[Pubmed: 30665040]
Biomedicine & PharmacotherapyOpuntioside, opuntiol and its metallic nanoparticles attenuate adjuvant-induced arthritis: Novel suppressors of Toll-like receptors-2 and-4[]
International Journal of ObesityCirculating microbiota-derived metabolites: a “liquid biopsy?[Pubmed: 31388096]
Scientific ReportsDeregulation of TLR4 signaling pathway characterizes Bicuspid Aortic valve syndrome[Pubmed: 31363123]
Life SciencesCrocin attenuates lung inflammation and pulmonary vascular dysfunction in a rat model of bleomycin-induced pulmonary fibrosis[Pubmed: 31465731]
Respiratory physiology & neurobiologyTargeting oxidative stress, proinflammatory cytokines, apoptosis and toll like receptor 4 by empagliflozin to ameliorate bleomycin-induced lung fibrosis[Pubmed: 31600583]
Thrombosis and haemostasisParticulate Shiga Toxin 2 in Blood is Associated to the Development of Hemolytic Uremic Syndrome in Children[Pubmed: 31858520]
J EthnopharmacolEffects of fermented ginseng on the gut microbiota and immunity of rats with antibiotic-associated diarrhea[Pubmed: 33217518]
International Journal of Molecular SciencesRelationship between IL-8 Circulating Levels and TLR2 Hepatic Expression in Women with Morbid Obesity and Nonalcoholic Steatohepatitis[Pubmed: 32545403]
NEUROPSYCHOBIOLOGYDiosgenin Attenuates Cognitive Impairment in Streptozotocin-Induced Diabetic Rats: Underlying Mechanisms[Pubmed: 32526752]
journal of biochemical and molecular toxicologyS‐allyl cysteine, an active ingredient of garlic, attenuates acute liver dysfunction induced by lipopolysaccharide/ d‐galactosamine in mouse: Underlying mechanisms[Pubmed: 32453893]
microbial pathogenesisProtective effect of diosgenin on LPS/D-Gal-induced acute liver failure in C57BL/6 mice[Pubmed: 32389705]
Sciences of EuropeFEATURES OF MYOCARDIAL REMODELING IN MEN WITH POST-INFARCTION CARDIOSCLEROSIS AND ITS RELATIONSHIP WITH TOLL-LIKE …[]
Putative anti-inflammatory, antioxidant, and anti-apoptotic roles of the natural tissue guardian methyl palmitate against isoproterenol-induced myocardial …[]
The role of Toll-like receptors-4 in the pathogenesis of development of anemia of inflammation in young children[]
Clin Oral InvestigEvaluation of heat shock protein 70 and toll-like receptor 4 expression in gingival crevicular fluid in response to orthodontic forces[34091792]
Eksp Klin GastroenterolTissue transglutaminase is involved in the inflammatory processes of active chronic gastritis[17539352]
Iranian Journal of Medical SciencesEsculetin Alleviates Acute Liver Failure following Lipopolysaccharide/D-Galactosamine in Male C57BL/6 Mice[]
Acta Obstet Gynecol ScandA value of soluble Toll‐like receptor 2 and 4 in vaginally obtained amniotic fluid for the prediction of histological chorioamnionitis[34244993]
NutrientsExpression of Jejunal Taste Receptors in Women with Morbid Obesity[34371946]
Biomed PharmacotherNifuroxazide-loaded cubosomes exhibit an advancement in pulmonary delivery and attenuate bleomycin-induced lung fibrosis by regulating the STAT3 and …[Pubmed:35220029]
Biomed PharmacotherCoomassie brilliant blue G-250 dye attenuates bleomycin-induced lung fibrosis by regulating the NF-κB and NLRP3 crosstalk: A novel approach for filling an …[Pubmed:35202914]
Frontiers in PharmacologyCarbocisteine as a Modulator of Nrf2/HO-1 and NFκB Interplay in Rats: New Inspiration for the Revival of an Old Drug for Treating Ulcerative Colitis. Front …[Pubmed:35754464]
ProcessesLipocalin, Resistin and Gut Microbiota-Derived Propionate Could Be Used to Predict Metabolic Bariatric Surgery Selected Outcomes[]
BiomoleculesVascular Calcification and the Gut and Blood Microbiome in Chronic Kidney Disease Patients on Peritoneal Dialysis: A Pilot Study[]