脑啡肽酶(CD10)多克隆抗体(生物素标记)
Biotin-Linked Polyclonal Antibody to Neprilysin (CD10)
NEP; MME; CALLA; SFE; Atriopeptidase; Enkephalinase; Skin fibroblast elastase; Common Acute Lymphoblastic Leukemia Antigen; Membrane Metallo-Endopeptidase
- 编号LAB785Ra71
- 物种Rattus norvegicus (Rat，大鼠)相同的名称，不同的物种。
- 来源抗体标记
- Ig类型IgG
- 纯化方式抗原特异性亲和纯化
- 标记物生物素
- 原抗体-
- 缓冲液成份磷酸盐缓冲液（pH7.4,含有0.02% NaN3和50%甘油）
- 性状液体
- 浓度500µg/mL
- 且适物种-
- 应用WB; IHC; ICC.
如果抗体需用于流式细胞术，请参见流式抗体。 - 下载英文说明书 中文说明书
- 规格20µl100µl200µl1ml10ml
- 价格¥ 716¥ 1672¥ 2388¥ 5970¥ 23880
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产品包装(模拟)
产品包装(模拟)
DAB staining on IHC-P;
Samples: Rat Kidney Tissue
Primary Ab: 20μg/ml Biotin-Linked Polyclonal Antibody to Neprilysin (CD10)
Second Ab: 2μg/ml HRP-Labeled Streptavidin (Catalog: IS089)
通过ISO 9001、ISO 13485质量体系认证
特异性
该抗体是针对CD10的兔多克隆抗体。在免疫组织化学染色和免疫印迹实验中能识别CD10。
用法
免疫印迹：0.2-2µg/mL;1:250-2500
免疫组织化学：5-20µg/mL;1:25-100
免疫细胞化学：5-20µg/mL;1:25-100
最佳稀释倍数最终由用户决定。
储存
经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。
稳定性
热稳定性以损失率显示。损失率是由加速降解试验决定，具体方法如下：在37°C孵育48小时，没有显著的降解或者沉淀产生。保质期内，在适当的条件下存储，损失率低于5%。
赠品
增值服务
相关产品
| 编号 | 适用物种：Rattus norvegicus (Rat，大鼠) | 应用(仅供研究使用，不用于临床诊断！) |
| RPB785Ra02 | 脑啡肽酶(CD10)重组蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPB785Ra01 | 脑啡肽酶(CD10)重组蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| PAB785Ra01 | 脑啡肽酶(CD10)多克隆抗体 | WB; IHC; ICC; IP. |
| PAB785Ra02 | 脑啡肽酶(CD10)多克隆抗体 | WB; IHC; ICC; IP. |
| LAB785Ra71 | 脑啡肽酶(CD10)多克隆抗体(生物素标记) | WB; IHC; ICC. |
| SEB785Ra | 脑啡肽酶(CD10)检测试剂盒(酶联免疫吸附试验法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| LMB785Ra | 脑啡肽酶(CD10)等多因子检测试剂盒(流式荧光发光法) | FLIA Kit for Antigen Detection. |
参考文献
| 杂志 | 参考文献 |
| 13 | Elevated Plasma levels of Neutral Endpeptidase in Hypertension Patients Treated with Angiotensin Converting Enzyme Inhibitors[Ahajournals:Source] |
| Biol Pharm Bull | Effect of High Glucose Levels on Amyloid β Production in Retinas of Spontaneous Diabetes Mellitus Otsuka Long-Evans Tokushima Fatty Rats[PubMed: 25832640] |
| Eur J Heart Fail. | Soluble neprilysin does not correlate with outcome in heart failure with preserved ejection fraction[Pubmed:26725876] |
| 8 | A Test in Context: Neprilysin: Function, Inhibition, and Biomarker.[pubmed:27491909] |
| European Journal of Heart Failure | Effects of sacubitril/valsartan on neprilysin targets and the metabolism of natriuretic peptides in chronic heart failure: a mechanistic clinical study[Pubmed: 30520545] |
| European Journal of Heart Failure | Increased granulocyte membrane neprilysin (CD10) expression is associated with better prognosis in heart failure[Pubmed: 30828920] |
| Clinical Research in Cardiology | Soluble neprilysin, NT-proBNP, and growth differentiation factor-15 as biomarkers for heart failure in dialysis patients (SONGBIRD)[Pubmed: 32002632] |
| Neurotoxicology | Involvement of hippocampal agmatine in β1-42 amyloid induced memory impairment, neuroinflammation and BDNF signaling disruption in mice[Pubmed: 32522471] |
| European Heart Journal | P1620 Association of granulocyte neprilysin (CD10) expression with prognosis in heart failure with reduced ejection fraction[] |
| Clin Biochem | Finding a reliable assay for soluble neprilysin[Pubmed:35331754] |
| Scientific Reports | The potential role of serum tau protein (MAPT), neuronal cell adhesion molecule (NrCAM) and neprilysin (NEP) in neurodegenerative disorders development in …[] |