穿孔素1(PRF1)多克隆抗体(生物素标记)
Biotin-Linked Polyclonal Antibody to Perforin 1 (PRF1)
FLH2; HPLH2; P1; PFP; Pore Forming Protein; Cytolysin; Lymphocyte pore-forming protein
- 编号LAB317Mu71
- 物种Mus musculus (Mouse，小鼠)相同的名称，不同的物种。
- 来源抗体标记
- Ig类型IgG
- 纯化方式抗原特异性亲和纯化
- 标记物生物素
- 原抗体-
- 缓冲液成份磷酸盐缓冲液（pH7.4,含有0.02% NaN3和50%甘油）
- 性状液体
- 浓度500µg/mL
- 且适物种-
- 应用WB; IHC; ICC.
如果抗体需用于流式细胞术，请参见流式抗体。 - 下载英文说明书 中文说明书
- 规格20µl100µl200µl1ml10ml
- 价格¥ 677¥ 1579¥ 2256¥ 5640¥ 22560
- 欲了解实际交易价格和更多情况，请与当地经销商联系!
产品包装(模拟)
产品包装(模拟)
通过ISO 9001、ISO 13485质量体系认证
特异性
该抗体是针对PRF1的兔多克隆抗体。在免疫组织化学染色和免疫印迹实验中能识别PRF1。
用法
免疫印迹：0.2-2µg/mL;1:250-2500
免疫组织化学：5-20µg/mL;1:25-100
免疫细胞化学：5-20µg/mL;1:25-100
最佳稀释倍数最终由用户决定。
储存
经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。
稳定性
热稳定性以损失率显示。损失率是由加速降解试验决定，具体方法如下：在37°C孵育48小时，没有显著的降解或者沉淀产生。保质期内，在适当的条件下存储，损失率低于5%。
赠品
增值服务
相关产品
| 编号 | 适用物种：Mus musculus (Mouse，小鼠) | 应用(仅供研究使用，不用于临床诊断！) |
| RPB317Mu01 | 穿孔素1(PRF1)重组蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPB317Mu02 | 穿孔素1(PRF1)重组蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| APB317Mu01 | 穿孔素1(PRF1)活性蛋白 | Cell culture; Activity Assays. |
| APB317Mu02 | 穿孔素1(PRF1)活性蛋白 | Cell culture; Activity Assays. |
| PAB317Mu01 | 穿孔素1(PRF1)多克隆抗体 | WB; IHC; ICC; IP. |
| PAB317Mu02 | 穿孔素1(PRF1)多克隆抗体 | WB; IHC; ICC; IP. |
| LAB317Mu81 | 穿孔素1(PRF1)多克隆抗体(异硫氰酸荧光素标记) | WB; IHC; ICC; IF. |
| LAB317Mu71 | 穿孔素1(PRF1)多克隆抗体(生物素标记) | WB; IHC; ICC. |
| WEB317Mu | 穿孔素1(PRF1)检测试剂盒(酶联免疫吸附试验法,宽范围) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| SEB317Mu | 穿孔素1(PRF1)检测试剂盒(酶联免疫吸附试验法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| LMB317Mu | 穿孔素1(PRF1)等多因子检测试剂盒(流式荧光发光法) | FLIA Kit for Antigen Detection. |
参考文献
| 杂志 | 参考文献 |
| Diagnostic Microbiology and Infectious Disease | Granzyme B as a diagnostic marker of tuberculosis in patients with and without HIV coinfection[Pubmed:26915636] |
| FASEB JOURNAL | The immunoregulatory effects of CD8 T-cell–derived perforin on diet-induced nonalcoholic steatohepatitis[Pubmed: 30951375] |
| Theranostics | A novel Granzyme B nanoparticle delivery system simulates immune cell functions for suppression of solid tumors[Pubmed: 31695790] |
| Mol Immunol | CD317 mediates immunocytolysis resistance by RICH2/cytoskeleton-dependent membrane protection[Pubmed: 33223223] |
| INVESTIGATIONAL NEW DRUGS | Dual-function chimeric antigen receptor T cells targeting c-Met and PD-1 exhibit potent anti-tumor efficacy in solid tumors[Pubmed: 32772342] |
| Am J Transl Res | Combined treatment with epigenetic agents enhances anti-tumor activity of T cells by upregulating the ACRBP expression in hepatocellular carcinoma[34377237] |
| Nat Biomed Eng | Cancer-cell stiffening via cholesterol depletion enhances adoptive T-cell immunotherapy[34873307] |
| J Exp Med | Single-cell immune profiling reveals functional diversity of T cells in tuberculous pleural effusion[Pubmed:35061012] |