硫酸肝素蛋白聚糖(HSPG)重组蛋白
Recombinant Heparan Sulfate Proteoglycan (HSPG)
SDC2; HSPG1; SYND2; Fibroglycan; Syndecan 2; Syndecan Proteoglycan 2; Heparan Sulfate Proteoglycan 1,Cell Surface-Associated; Heparan Sulphate Proteoglycan
- 编号RPA565Ra01
- 物种Rattus norvegicus (Rat，大鼠)相同的名称，不同的物种。
- 来源原核表达
- 宿主E.coli
- 内毒素水平<1.0EU/µg(LAL法测定)
- 亚细胞定位细胞膜
- 预测分子量17.6kDa
- 实际分子量26kDa(差异分析请参阅说明书)
- 片段与标签Glu19~Glu144 with N-terminal His Tag
- 缓冲液成份PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
- 性状冻干粉
- 纯度> 90%
- 等电点3.9
- 应用Positive Control; Immunogen; SDS-PAGE; WB.
如果需要有生物活性的蛋白，请参见活性蛋白。 - 下载英文说明书 中文说明书
- 规格10µg50µg200µg1mg5mg
- 价格¥ 1166¥ 2916¥ 5832¥ 17496¥ 43740
- 欲了解实际交易价格和更多情况，请与当地经销商联系!
产品包装(模拟)
产品包装(模拟)
Figure. SDS-PAGE
通过ISO 9001、ISO 13485质量体系认证
序列
用法
Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
储存
避免反复冻融。2-8°C不超过一个月，-80°C不超过12个月。
稳定性
热稳定性以损失率显示。损失率是由加速降解试验决定，具体方法如下：在37°C孵育48小时，没有显著的降解或者沉淀产生。保质期内，在适当的条件下存储，损失率低于5%。
增值服务
相关产品
| 编号 | 适用物种：Rattus norvegicus (Rat，大鼠) | 应用(仅供研究使用，不用于临床诊断！) |
| RPA565Ra01 | 硫酸肝素蛋白聚糖(HSPG)重组蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| PAA565Ra01 | 硫酸肝素蛋白聚糖(HSPG)多克隆抗体 | WB; IHC; ICC; IP. |
| SEA565Ra | 硫酸肝素蛋白聚糖(HSPG)检测试剂盒(酶联免疫吸附试验法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| LMA565Ra | 硫酸肝素蛋白聚糖(HSPG)等多因子检测试剂盒(流式荧光发光法) | FLIA Kit for Antigen Detection. |
参考文献
| 杂志 | 参考文献 |
| Journal of Applied Pharmaceutical Science | Cytotoxic effects of antiglypican-3 against HepG3 cell line[Ebscohost: Source] |
| Journal of Reproductive Immunology | Fibrinogen, an endogenous ligand of Toll-like receptor 4, activates monocytes in pre-eclamptic patients[Pubmed: 24661950] |
| European journal of pharmacology | Suramin inhibits hepatic tissue damage in hepatocellular carcinoma through deactivation of heparanase enzyme[Pubmed: 24530413] |
| European Journal of Pharmacology | Evaluation of antiglypican-3 therapy as a promising target for amelioration of hepatic tissue damage in hepatocellular carcinoma[Pubmed:25449037] |
| Shock | Impairment of the Endothelial Glycocalyx in Cardiogenic Shock and its Prognostic Relevance[Pubmed:25692257] |
| Biomarkers in Medicine | Endothelial glycocalyx layer shedding following lung resection[pubmed:27643669] |
| Apmis | Circulating syndecans during critical illness.[pubmed:28256016] |
| Biomedicine & Pharmacotherapy | Cytotoxic and partial hepatoprotective activity of sodium ascorbate against hepatocellular carcinoma through inhibition of sulfatase-2 and[Pubmed:29669302] |
| Drug Delivery | Glioma targeting peptide modified apoferritin nanocage[Pubmed:29726297] |
| Anaesthesia | Postoperative microcirculatory perfusion and endothelial glycocalyx shedding following cardiac surgery with cardiopulmonary bypass[Pubmed: 30687934] |
| Animals | Diet Supplementation with a Bioactive Pomace Extract from Olea europaea Partially Mitigates Negative Effects on Gut Health Arising from a Short-Term Fasting Period …[] |
| LIFE SCIENCES | Heparin prevents in vitro glycocalyx shedding induced by plasma from COVID-19 patients[33781826] |
| Genet Mol Biol | A novel mutation in ext2 caused hereditary multiple exostoses through reducing the synthesis of heparan sulfate[34042151] |
| Poultry Science | Response of broiler chickens fed diets supplemented with a bioactive olive pomace extract from Olea europaea to an experimental coccidial vaccine?¡[33518110] |
| J Gerontol A Biol Sci Med Sci | The effect of pre-operative methylprednisolone on postoperative delirium in elderly patients undergoing gastrointestinal surgery: a randomized, double-blind, placebo …[34423832] |