武汉云克隆科技股份有限公司

低氧诱导因子1α(HIF1a)重组蛋白

Recombinant Hypoxia Inducible Factor 1 Alpha (HIF1a)

HIF1-A; MOP1; PASD8; Basic Helix-Loop-Helix Transcription Factor; ARNT-interacting protein; Basic-helix-loop-helix-PAS protein MOP1; Class E basic helix-loop-helix protein 78

  • 低氧诱导因子1α(HIF1a)重组蛋白产品包装(模拟)
  • 低氧诱导因子1α(HIF1a)重组蛋白产品包装(模拟)
  • 低氧诱导因子1α(HIF1a)重组蛋白Figure . Gene Sequencing (extract)
  • RPA798Hu02.jpgFigure. SDS-PAGE
  • Certificate通过ISO 9001、ISO 13485质量体系认证

序列

用法

Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

储存

避免反复冻融。2-8°C不超过一个月，-80°C不超过12个月。

稳定性

热稳定性以损失率显示。损失率是由加速降解试验决定，具体方法如下：在37°C孵育48小时，没有显著的降解或者沉淀产生。保质期内，在适当的条件下存储，损失率低于5%。

相关产品

编号适用物种：Homo sapiens (Human，人)应用(仅供研究使用，不用于临床诊断！)
APA798Hu02低氧诱导因子1α(HIF1a)活性蛋白Cell culture; Activity Assays.
RPA798Hu01低氧诱导因子1α(HIF1a)重组蛋白Positive Control; Immunogen; SDS-PAGE; WB.
RPA798Hu02低氧诱导因子1α(HIF1a)重组蛋白Positive Control; Immunogen; SDS-PAGE; WB.
PAA798Hu01低氧诱导因子1α(HIF1a)多克隆抗体WB; IHC
PAA798Hu02低氧诱导因子1α(HIF1a)多克隆抗体WB; IHC
LAA798Hu81低氧诱导因子1α(HIF1a)多克隆抗体(异硫氰酸荧光素标记)WB; IHC; ICC; IF.
LAA798Hu71低氧诱导因子1α(HIF1a)多克隆抗体(生物素标记)WB; IHC; ICC.
MAA798Hu21低氧诱导因子1α(HIF1a)单克隆抗体WB; IHC; ICC; IP.
MAA798Hu23低氧诱导因子1α(HIF1a)单克隆抗体WB; IHC; ICC; IP.
MAA798Hu24低氧诱导因子1α(HIF1a)单克隆抗体WB; IHC; ICC; IP.
MAA798Hu25低氧诱导因子1α(HIF1a)单克隆抗体WB; IHC; ICC; IP.
MAA798Hu22低氧诱导因子1α(HIF1a)单克隆抗体WB; IHC; ICC; IP.
MAA798Hu27低氧诱导因子1α(HIF1a)单克隆抗体WB; IHC; ICC; IP.
MAA798Hu29低氧诱导因子1α(HIF1a)单克隆抗体WB; IHC; ICC; IP.
SEA798Hu低氧诱导因子1α(HIF1a)检测试剂盒(酶联免疫吸附试验法)Enzyme-linked immunosorbent assay for Antigen Detection.
MEA798Hu低氧诱导因子1α(HIF1a)检测试剂盒(酶联免疫吸附试验法,小样本)Enzyme-linked immunosorbent assay for Antigen Detection.
HEA798Hu低氧诱导因子1α(HIF1a)检测试剂盒(酶联免疫吸附试验法,高敏型)Enzyme-linked immunosorbent assay for Antigen Detection.
SCA798Hu低氧诱导因子1α(HIF1a)检测试剂盒(化学发光免疫分析法)Chemiluminescent immunoassay for Antigen Detection.
LMA798Hu低氧诱导因子1α(HIF1a)等多因子检测试剂盒(流式荧光发光法)FLIA Kit for Antigen Detection.
KSA798Hu01低氧诱导因子1α(HIF1a)检测试剂盒DIY材料(酶联免疫吸附试验法)Main materials for "Do It (ELISA Kit) Yourself".

参考文献

杂志参考文献
Cancer Chemotherapy and PharmacologyQuercetin greatly improved therapeutic index of doxorubicin against 4T1 breast cancer by its opposing effects on HIF-1α in tumor and normal cells.[PubMed: 19466611]
European Journal of PharmacologyBaicalin suppresses lung carcinoma and lung metastasis by SOD mimic and HIF-1α inhibition[ScienceDirect: S0014299909011352]
PLoS ONELactate Dehydrogenase 5 Expression in Non-Hodgkin Lymphoma Is Associated with the Induced Hypoxia Regulated Protein and Poor Prognosis[PubMed: PMC3781153]
International Journal of Molecular Medicine Selective inhibition of PKCβ2 preserves cardiac function after myocardial infarction and is associated with improved angiogenesis of ischemic myocardium in diabetic rats[Pubmed: 24002353]
Canadian Journal of Physiology and PharmacologyModulation of arginine and asymmetric dimethylarginine concentrations in liver and plasma by exogenous hydrogen sulfide in LPS-induced endotoxemia[Pubmed: 24289078]
US8569372 B2Method for preventing or treating a disease, disorder or condition induced by retina ischemia[US8569372]
J Surg Res. Effects of adrenomedullin and vascular endothelial growth factor on ischemia/reperfusion injury in skeletal muscle in rats.[Pubmed: 23816242]
PLoS One.HIF-1α Is Essential for Effective PMN Bacterial Killing, Antimicrobial Peptide Production and Apoptosis in Pseudomonas aeruginosa Keratitis[Plos: Source]
Journal of Physiological AnthropologyTelomeres are elongated in rats exposed to moderate altitude[Pubmed:Pmc4088304]
Molecular Medicine ReportsResveratrol abrogates the effects of hypoxia on cell proliferation, invasion and EMT in osteosarcoma cells through downregulation of the HIF-1α protein.[Pubmed:25384583]
International Journal of PharmaceuticsThe enhancement of gene silencing efficiency with chitosan-coated liposome formulations of siRNAs targeting HIF-1α and VEGF[Pubmed:25445537]
International Journal of Molecular MedicineEffect of combined treatment with rosuvastatin and protein kinase Cβ2 inhibitor on angiogenesis following myocardial infarction in diabetic rats[Pubmed:25524396]
International Journal of Developmental NeuroscienceMaternal omega-3 fatty acid supplementation to a vitamin B 12 deficient diet normalizes angiogenic markers in the pup brain at birth[PubMed: 25889224]
Eur Surg ResDetermination of the Preferred Conditions for the Isolated Perfusion of Porcine Kidneys[PubMed: 25341590]
Sci RepOxygen-induced cell migration and on-line monitoring biomarkers modulation of cervical cancers on a microfluidic system[PubMed: 25905434]
Evidence-Based Complementary and Alternative MedicineMetabolomic Analysis of Biochemical Changes in the Plasma of High-Fat Diet and Streptozotocin-Induced Diabetic Rats after Treatment with Isoflavones Extract of Radix Puerariae[pmc:PMC4794592]
Biol Trace Elem Res.Roles of Copper in Hepatocarcinogenesis via the Activation of Hypoxia-Inducible Factor-1α[Pubmed:27121973]
Раны и раневые инфекции.Использование гипоксического прекондиционирования для подготовки аутодермотрансплантата у больных со скомпрометированной микроциркуляцией[91]
Biological Trace Element ResearchRoles of Copper in Hepatocarcinogenesis via the Activation of Hypoxia-Inducible Factor-1α.[pubmed:27121973]
Experimental and Therapeutic MedicineExpression of hypoxia-inducible factor-1α in synovial fluid and articular cartilage is associated with disease severity in knee osteoarthritis[etm:13]
Clinical Trials in Degenerative DiseasesCorrelating oxidative stress-related factors with bone metabolic markers in older adult male patients exhibiting degenerative osteoporosis in the high-altitude hypoxic area of China: study protocol for a non-randomized controlled trial[issn:2542-3975]
Annals of Clinical & Laboratory ScienceR132H Mutation in IDH1 Gene is Associated with Increased Tumor HIF1-Alpha and Serum VEGF Levels in Primary Glioblastoma Multiforme [pubmed:28667042]
Archives of Gynecology and ObstetricsIs there any relationship between adipocytokines and angiogenesis factors to address endothelial dysfunction and platelet aggregation in untreated patients with preeclampsia?[10.1007/s00404-017-4461-2]
EXPERIMENTAL AND THERAPEUTIC MEDICINEExpression of hypoxia-inducible factor-1α in synovial fluid and articular cartilage is associated with disease severity in knee[pubmed:28123469]
Medical Journal Armed Forces IndiaStudy of acute hypoxia markers in healthy subjects: Utility in post-crash investigation[10.1016/j.mjafi.2017.04.003]
Journal of Physiological AnthropologyTelomere elongation protects heart and lung tissue cells from fatal damage in rats exposed to severe hypoxia[Pubmed:29454386]
Bulletin of Experimental Biology and MedicineSignal Mechanism of the Protective Effect of Combined Preconditioning by Amtizole and Moderate Hypoxia[Pubmed:29308565]
Microchimica ActaDetermination of hypoxia-inducible factor-1 by using a ratiometric colorimetric test based on click-mediated growth of gold nanoparticles[Pubmed: 30209641]
Bulletin of Experimental Biology and MedicineExpression of Hif-1α, Nf-κb, and Vegf Genes in the Liver and Blood Serum Levels of HIF-1α, Erythropoietin, VEGF, TGF-β, 8-Isoprostane, and Corticosterone in Wistar Rats with High and Low Resistance to Hypoxia. Corticosterone in …[Pubmed: 30353332]
Translational OncologyOKN-007 Increases temozolomide (TMZ) Sensitivity and Suppresses TMZ-Resistant Glioblastoma (GBM) Tumor Growth[Pubmed: 30468988]
West Indian Medical JournalPlasma Cellular Hypoxia, Mitochondrial Dysfunction, Disease Risk and Prognostic Factors in Type 2 Diabetic Patients in Saudi Arabia.[]
Bulletin of Experimental Biology and MedicineAge-Specific Features of Hypoxia Tolerance and Intensity of Lipopolysaccharide-Induced Systemic Inflammatory Response in Wistar Rats[Pubmed: 30903510]
The role of amniotic fluid exosome, hypoxia inducible fator-1α, and inflammatory cytokine in cervical insufficiency[]
scandinavian journal of immunologyVitexin alleviates interleukin‐1β induced inflammatory responses in chondrocytes from osteoarthritis patients: involvement of HIF‐1α pathway[Pubmed: 31055848]
JOURNAL OF PERIODONTOLOGYA disintegrin‐like and metalloproteinase with thrombospondin‐1 (ADAMTS‐1) levels in gingival crevicular fluid correlate with vascular endothelial growth factor‐A …[Pubmed: 31020669]
Tissue Eng Part AHypoxia Preconditioned Adipose Derived Endothelial Progenitor Cells Promote Bladder Augmentation[Pubmed: 31238789]
ПОТЕНЦИРОВАНИЕ АНТИГИПОКСАНТАМИ ЭФФЕКТА ГИПОКСИЧЕСКОГО ПРЕКОНДИЦИОНИРОВАНИЯ[]
molecular and cellular biochemistryMaternal omega-3 fatty acids and vitamin E improve placental angiogenesis in late-onset but not early-onset preeclampsia[Pubmed: 31420792]
MoleculesRegulation of MicroRNA-155 and Its Related Genes Expression by Inositol Hexaphosphate in Colon Cancer Cells[Pubmed: 31744065]
Stem Cell Res TherShort-wave enhances mesenchymal stem cell recruitment in fracture healing by increasing HIF-1 in callus[Pubmed: 32894200]
J Cell PhysiolPLCε regulates metabolism and metastasis signaling via HIF‐1α/MEK/ERK pathway in prostate cancer[Pubmed: 32383180]
Гипоксия-зависимый транскрипционный контроль активности деструктивных изменений пародонта воспалительного и злокачественного генеза[]
Food FunctPrenatal vitamin D supplementation reduces blood pressure and improves placental angiogenesis in an animal model of preeclampsia[33237074]
Eur J PharmacolLactucaxanthin protects retinal pigment epithelium from hyperglycemia-regulated hypoxia/ER stress/VEGF pathway mediated angiogenesis in ARPE-19 cell and rat ¡­[33705802]
EXPERIMENTAL EYE RESEARCHAstaxanthin mediated regulation of VEGF through HIF1¦Á and XBP1 signaling pathway: An insight from ARPE-19 cell and streptozotocin mediated diabetic rat model[33789142]
scientific reportsSerum hypoxia-inducible factor-1¦Á and uterine artery Doppler ultrasound during the first trimester for prediction of preeclampsia[33758274]
Molecular Biology ReportsUmbilical cord-derived mesenchymal stem cell conditioned medium reverses neuronal oxidative injury by inhibition of TRPM2 activation and the JNK signaling …[Pubmed:35585377]