T-细胞可诱导共刺激分子(ICOS)重组蛋白
Recombinant Inducible T-Cell Co Stimulator (ICOS)
CD278; AILIM; Inducible T-Cell Costimulator; Activation-Inducible Lymphocyte Immunomediatory Molecule
- 编号RPA777Mu01
- 物种Mus musculus (Mouse，小鼠)相同的名称，不同的物种。
- 来源原核表达
- 宿主E.coli
- 内毒素水平<1.0EU/µg(LAL法测定)
- 亚细胞定位细胞膜
- 预测分子量12.2kDa
- 实际分子量12kDa(差异分析请参阅说明书)
- 片段与标签Asn35~Ile131 with N-terminal His Tag
- 缓冲液成份20mM Tris, 150mM NaCl缓冲液（pH8.0, 含有1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose和Proclin300）
- 性状冻干粉
- 纯度> 90%
- 等电点7.8
- 应用Positive Control; Immunogen; SDS-PAGE; WB.
如果需要有生物活性的蛋白，请参见活性蛋白。 - 下载英文说明书 中文说明书
- 规格10µg50µg200µg1mg5mg
- 价格¥ 1008¥ 2520¥ 5040¥ 15120¥ 37800
- 欲了解实际交易价格和更多情况，请与当地经销商联系!
产品包装(模拟)
产品包装(模拟)
SDS-PAGE图
通过ISO 9001、ISO 13485质量体系认证
序列
用法
Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
储存
避免反复冻融。2-8°C不超过一个月，-80°C不超过12个月。
稳定性
热稳定性以损失率显示。损失率是由加速降解试验决定，具体方法如下：在37°C孵育48小时，没有显著的降解或者沉淀产生。保质期内，在适当的条件下存储，损失率低于5%。
增值服务
相关产品
| 编号 | 适用物种：Mus musculus (Mouse，小鼠) | 应用(仅供研究使用，不用于临床诊断！) |
| RPA777Mu01 | T-细胞可诱导共刺激分子(ICOS)重组蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| PAA777Mu01 | T-细胞可诱导共刺激分子(ICOS)多克隆抗体 | WB; IHC; ICC; IP. |
| LAA777Mu71 | T-细胞可诱导共刺激分子(ICOS)多克隆抗体(生物素标记) | WB; IHC; ICC. |
参考文献
| 杂志 | 参考文献 |
| Archives of Dermatological Research | Increased production of soluble inducible costimulator in patients with diffuse cutaneous systemic sclerosis[Pubmed: 23053221] |
| DNA Cell Biol. | Effect of soluble inducible costimulator level and its polymorphisms on age-related macular degeneration.[Pubmed: 24083358] |
| Rheumatology | Augmented ICOS expression in patients with early diffuse cutaneous systemic sclerosis[Pubmed: 23024058] |
| Br J Haematol | Inducible T‐cell co‐stimulator (ICOS) and ICOS ligand are novel players in the multiple‐myeloma microenvironment[Pubmed:34954822] |
| Diagnostics (Basel) | Increased Levels of ICOS and ICOSL Are Associated to Pulmonary Arterial Hypertension in Patients Affected by Connective Tissue Diseases[Pubmed:35328257] |