异柠檬酸脱氢酶1(IDH1)重组蛋白
Recombinant Isocitrate Dehydrogenase 1, Soluble (IDH1)
PICD; IDP; Oxalosuccinate decarboxylase; NADP(+)-specific ICDH; Cytosolic NADP-isocitrate dehydrogenase
- 编号RPH839Mu01
- 物种Mus musculus (Mouse，小鼠)相同的名称，不同的物种。
- 来源原核表达
- 宿主E.coli
- 内毒素水平<1.0EU/µg(LAL法测定)
- 亚细胞定位Cytoplasm
- 预测分子量57.6kDa
- 实际分子量55kDa(差异分析请参阅说明书)
- 片段与标签Ile99~Thr325 (Accession # O88844) with N-terminal His and GST Tag
- 缓冲液成份磷酸盐缓冲液（pH7.4，含有 0.01% SKL, 1mM DTT, 5% Trehalose和Proclin300.）
- 性状冻干粉
- 纯度> 95%
- 等电点6.5
- 应用Positive Control; Immunogen; SDS-PAGE; WB.
如果需要有生物活性的蛋白，请参见活性蛋白。 - 下载英文说明书 中文说明书
- 规格10µg50µg200µg1mg5mg
- 价格¥ 1056¥ 2640¥ 5280¥ 15840¥ 39600
- 欲了解实际交易价格和更多情况，请与当地经销商联系!
产品包装(模拟)
产品包装(模拟)
SDS-PAGE图
通过ISO 9001、ISO 13485质量体系认证
序列
用法
PBS或其它。
储存
避免反复冻融。2-8°C不超过一个月，-80°C不超过12个月。
稳定性
热稳定性以损失率显示。损失率是由加速降解试验决定，具体方法如下：在37°C孵育48小时，没有显著的降解或者沉淀产生。保质期内，在适当的条件下存储，损失率低于5%。
增值服务
相关产品
| 编号 | 适用物种：Mus musculus (Mouse，小鼠) | 应用(仅供研究使用，不用于临床诊断！) |
| RPH839Mu01 | 异柠檬酸脱氢酶1(IDH1)重组蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| PAH839Mu01 | 异柠檬酸脱氢酶1(IDH1)多克隆抗体 | WB; IHC; ICC; IP. |
| LAH839Mu81 | 异柠檬酸脱氢酶1(IDH1)多克隆抗体(异硫氰酸荧光素标记) | WB; IHC; ICC; IF. |
| LAH839Mu71 | 异柠檬酸脱氢酶1(IDH1)多克隆抗体(生物素标记) | WB; IHC; ICC. |
参考文献
| 杂志 | 参考文献 |
| Molecular & Cellular Proteomics | Identification of IDH1 as a Potential Diagnostic and Prognostic Biomarker for Non-small-cell Lung Cancer by Proteomic Analysis[Mcponline: 008821] |
| Molecular & Cellular Proteomics | Identification of Isocitrate Dehydrogenase 1 as a Potential Diagnostic and Prognostic Biomarker for Non-small Cell Lung Cancer by Proteomic Analysis[Pubmed: 22064513] |
| Clinical Cancer Research | Isocitrate dehydrogenase 1 is a novel plasma biomarker for the diagnosis of non-small cell lung cancer[Pubmed: 24046070] |
| Onco Targets Ther | The effects of PGC-1α on the proliferation and energy metabolism of malignant endometrial cancer cells[PubMed: 25914546] |
| Oncogene | Metformin sensitizes endometrial cancer cells to chemotherapy through IDH1-induced Nrf2 expression via an epigenetic mechanism[Pubmed:29921847] |
| Molecular Oncology | IDH 2 is a novel diagnostic and prognostic serum biomarker for non‐small‐cell lung cancer[Pubmed:29465809] |
| Cancers | Serological Biomarkers for Early Detection of Hepatocellular Carcinoma: A Focus on Autoantibodies against Tumor-Associated Antigens Encoded by Cancer Driver …[Pubmed: 32443439] |
| International Journal of Cancer | Proteome profiling of enzalutamide‐resistant cell lines and serum analysis identified ALCAM as marker of resistance in castration‐resistant prostate cancer[Pubmed:35689436] |