武汉云克隆科技股份有限公司

血小板反应蛋白解整合素金属肽酶5(ADAMTS5)单克隆抗体

Monoclonal Antibody to A Disintegrin And Metalloproteinase With Thrombospondin 5 (ADAMTS5)

ADMP-2; Aggrecanase-2

  • 血小板反应蛋白解整合素金属肽酶5(ADAMTS5)单克隆抗体产品包装(模拟)
  • 血小板反应蛋白解整合素金属肽酶5(ADAMTS5)单克隆抗体产品包装(模拟)
  • Certificate通过ISO 9001、ISO 13485质量体系认证

特异性

该抗体是针对ADAMTS5的小鼠单克隆抗体。在免疫组织化学染色和免疫印迹实验中能识别ADAMTS5。

用法

免疫印迹：0.2-2µg/mL;1:500-5000
免疫组织化学：5-20µg/mL;1:50-200
免疫细胞化学：5-20µg/mL;1:50-200
最佳稀释倍数最终由用户决定。

储存

经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。

稳定性

热稳定性以损失率显示。损失率是由加速降解试验决定，具体方法如下：在37°C孵育48小时，没有显著的降解或者沉淀产生。保质期内，在适当的条件下存储，损失率低于5%。

赠品

相关产品

编号适用物种：Homo sapiens (Human，人)应用(仅供研究使用，不用于临床诊断！)
RPK205Hu01血小板反应蛋白解整合素金属肽酶5(ADAMTS5)重组蛋白Positive Control; Immunogen; SDS-PAGE; WB.
PAK205Hu01血小板反应蛋白解整合素金属肽酶5(ADAMTS5)多克隆抗体WB; IHC; ICC; IP.
MAK205Hu21血小板反应蛋白解整合素金属肽酶5(ADAMTS5)单克隆抗体WB; IHC; ICC; IP.
SEK205Hu血小板反应蛋白解整合素金属肽酶5(ADAMTS5)检测试剂盒(酶联免疫吸附试验法)Enzyme-linked immunosorbent assay for Antigen Detection.
LMK205Hu血小板反应蛋白解整合素金属肽酶5(ADAMTS5)等多因子检测试剂盒(流式荧光发光法)FLIA Kit for Antigen Detection.
KSK205Hu01血小板反应蛋白解整合素金属肽酶5(ADAMTS5)检测试剂盒DIY材料(酶联免疫吸附试验法)Main materials for "Do It (ELISA Kit) Yourself".

参考文献

杂志参考文献
PLoS ONEA Combinatorial Relative Mass Value Evaluation of Endogenous Bioactive Proteins in Three-Dimensional Cultured Nucleus Pulposus Cells of Herniated Intervertebral Discs: Identification of Potential Target Proteins for Gene Therapeutic Approaches[Plosone: Source]
Osteoarthritis and CartilageLack of anti-inflammatory and anti-catabolic effects on basal inflamed osteoarthritic chondrocytes or synoviocytes by adipose stem cell-conditioned medium[PubMed: 26521751]
Journal of Cellular and Molecular MedicineVIP and CRF reduce ADAMTS expression and function in osteoarthritis synovial fibroblasts[Pubmed:26818776]
Int Wound J.From varices to venous ulceration: the story of chronic venous disease described by metalloproteinases.[Pubmed:26991748]
The American journal of pathologyHealthy and Osteoarthritic Synovial Fibroblasts Produce a Disintegrin and Metalloproteinase with Thrombospondin Motifs 4, 5, 7, and 12: Induction by IL-1β and Fibronectin and Contribution to Cartilage Damage.[pubmed:27449198]
PLoS One.Self-complementary adeno-associated virus serotype 6 mediated knockdown of ADAMTS4 induces long-term and effective enhancement of aggrecan in degenerative human nucleus pulposus cells: A new therapeutic approach for intervertebral disc disorders.[pubmed:28207788]
PLoS OneSelf-complementary adeno-associated virus serotype 6 mediated knockdown of ADAMTS4 induces long-term and effective enhancement of aggrecan in degenerative human nucleus pulposus cells: A new therapeutic approach for intervertebral disc disorders[10.1371:journal.pone.0172181]
International Wound JournalFrom varices to venous ulceration: the story of chronic venous disease described by metalloproteinases[pubmed:26991748]
BMC musculoskeletal disordersHemoglobin stimulates the expression of ADAMTS-5 and ADAMTS-9 by synovial cells: a possible cause of articular cartilage damage after intra-articular hemorrhage.[pubmed:29137610]
Journal of Clinical MedicineThe Effects of TNF-α Inhibition on the Metabolism of Cartilage: Relationship between KS, HA, HAPLN1 and ADAMTS4, ADAMTS5, TOS and TGF-β1 Plasma …[Pubmed:35407621]