α-黑素细胞刺激素(aMSH)单克隆抗体
Monoclonal Antibody to Alpha-Melanocyte Stimulating Hormone (aMSH)
α-MSH; Intermedins; Alpha-Melanotropin, Alpha-Melanocortin; Alpha-Intermedin
- 编号MAA239Mi22
- 物种相同的名称，不同的物种。
- 来源单抗制备
- 宿主小鼠
- 效价(克隆号)C4
- Ig亚型 IgG1 Kappa
- 纯化方式蛋白A + 蛋白G亲和纯化
- 标记物无标记物
- 免疫原CPA239Mi21-α-黑素细胞刺激素(aMSH)卵白蛋白偶联物
- 缓冲液成份磷酸盐缓冲液（pH7.4,含有0.02% NaN3和50%甘油）
- 性状液体
- 浓度1mg/mL
- 且适物种-
- 应用WB; IHC; ICC; IP.
如果抗体需用于流式细胞术，请参见流式抗体。 - 下载英文说明书 中文说明书
- 规格20µl100µl200µl1ml10ml
- 价格¥ 657¥ 1533¥ 2190¥ 5475¥ 21900
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产品包装(模拟)
产品包装(模拟)
DAB staining on IHC-P;
Sample: Porcine Pituitary Tissue
Primary Ab: 30µg/ml Mouse Anti-Multi-species aMSH Antibody
Control: Used PBS instead of primary antibody
Second Ab: 2μg/ml HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody
(Catalog: SAA544Mu19)
通过ISO 9001、ISO 13485质量体系认证
特异性
该抗体是针对aMSH的小鼠单克隆抗体。在免疫组织化学染色和免疫印迹实验中能识别aMSH。
用法
Western blotting: 0.01-2µg/mL;
Immunohistochemistry: 5-20µg/mL;
Immunocytochemistry: 5-20µg/mL;
Optimal working dilutions must be determined by end user.
储存
经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。
稳定性
热稳定性以损失率显示。损失率是由加速降解试验决定，具体方法如下：在37°C孵育48小时，没有显著的降解或者沉淀产生。保质期内，在适当的条件下存储，损失率低于5%。
赠品
相关产品
| 编号 | 适用物种： | 应用(仅供研究使用，不用于临床诊断！) |
| CPA239Mi21 | α-黑素细胞刺激素(aMSH)卵白蛋白偶联物 | Immunogen; SDS-PAGE; WB. |
| SPA239Mi01 | α-黑素细胞刺激素(aMSH)合成多肽 | Immunogen; Blocking Peptide. |
| PAA239Mi08 | α-黑素细胞刺激素(aMSH)多克隆抗体 | WB; IHC; ICC; IP. |
| MAA239Mi21 | α-黑素细胞刺激素(aMSH)单克隆抗体 | WB; IHC; ICC; IP. |
| MAA239Mi22 | α-黑素细胞刺激素(aMSH)单克隆抗体 | WB; IHC; ICC; IP. |
参考文献
| 杂志 | 参考文献 |
| J Biochem. | Generation of a human bone marrow-derived mesenchymal stem cell line expressing and secreting high levels of bioactive α-melanocyte-stimulating hormone.[Pubmed: 23341471] |
| Pigment Cell Melanoma Res | Pharmacological induction of skin pigmentation unveils the neuroendocrine circuit regulated by light[PubMed: 26582755] |
| The Journal of Biological Chemistry | Intermedin Restores Hyperhomocysteinemia-induced Macrophage Polarization and Improves Insulin Resistance in Mice[Pubmed:27080257] |
| Pigment Cell & Melanoma Research | Pharmacological induction of skin pigmentation unveils the neuroendocrine circuit reCavia (Guinea pig )lated by light[Pubmed:26582755] |
| Nature Communications | Endocrine disruptors induce perturbations in endoplasmic reticulum and mitochondria of human pluripotent stem cell derivatives.[pubmed:28794470] |
| Cell Stem Cell | Super-Obese Patient-Derived iPSC Hypothalamic Neurons Exhibit Obesogenic Signatures and Hormone Responses[Pubmed:29681516] |
| European Neuropsychopharmacology | Epigenetic alterations of the POMC promoter in tobacco dependence[Pubmed:29871818] |
| Neuropeptides | Mechanisms of sustained long-term weight loss after RYGB: α-MSH is a key factor[Pubmed:29685637] |
| Neuropsychobiology | Alcohol Withdrawal and Proopiomelanocortin Neuropeptides in an Animal Model of Alcohol Dependence[Pubmed: 31117084] |
| INTERNATIONAL IMMUNOPHARMACOLOGY | Intermedin alleviates the inflammatory response and stabilizes the endothelial barrier in LPS-induced ARDS through the PI3K/Akt/eNOS signaling pathway[Pubmed: 32892076] |
| J Endocrinol Invest | Serum alpha-melanocyte-stimulating hormone (a-MSH), brain-derived neurotrophic factor (BDNF), and agouti-related protein (AGRP) levels in children with Prader …[Pubmed:35098494] |