血管紧张素Ⅱ(AngII)单克隆抗体

Monoclonal Antibody to Angiotensin II (AngII)

Ang-II; Angiotensin-2

  • 血管紧张素Ⅱ(AngII)单克隆抗体产品包装(模拟)
  • 血管紧张素Ⅱ(AngII)单克隆抗体产品包装(模拟)
  • Certificate通过ISO 9001、ISO 13485质量体系认证

特异性

该抗体是针对AngII的小鼠单克隆抗体。在免疫组织化学染色和免疫印迹实验中能识别AngII。

用法

Western blotting: 0.01-2µg/mL;
Immunohistochemistry: 5-20µg/mL;
Immunocytochemistry: 5-20µg/mL;
Optimal working dilutions must be determined by end user.

储存

经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。

稳定性

热稳定性以损失率显示。损失率是由加速降解试验决定,具体方法如下:在37°C孵育48小时,没有显著的降解或者沉淀产生。保质期内,在适当的条件下存储,损失率低于5%。

赠品

相关产品

编号适用物种:Homo sapiens (Human,人)应用(仅供研究使用,不用于临床诊断!)
CPA005Hu21血管紧张素Ⅱ(AngII)卵白蛋白偶联物Immunogen; SDS-PAGE; WB.
PAA005Hu01血管紧张素Ⅱ(AngII)多克隆抗体WB; IHC; ICC; IP.
LAA005Hu81血管紧张素Ⅱ(AngII)多克隆抗体(异硫氰酸荧光素标记)WB; IHC; ICC; IF.
LAA005Hu71血管紧张素Ⅱ(AngII)多克隆抗体(生物素标记)WB; IHC; ICC.
MAA005Hu22血管紧张素Ⅱ(AngII)单克隆抗体WB; IHC; ICC; IP.
CEA005Hu血管紧张素Ⅱ(AngII)检测试剂盒(酶联免疫吸附试验法)Enzyme-linked immunosorbent assay for Antigen Detection.
CCA005Hu血管紧张素Ⅱ(AngII)检测试剂盒(化学发光免疫分析法)Chemiluminescent immunoassay for Antigen Detection.
LMA005Hu血管紧张素Ⅱ(AngII)等多因子检测试剂盒(流式荧光发光法)FLIA Kit for Antigen Detection.
KSA005Hu11血管紧张素Ⅱ(AngII)检测试剂盒DIY材料(酶联免疫吸附试验法)Main materials for "Do It (ELISA Kit) Yourself".

参考文献

杂志参考文献
Nature MedicineAngiotensin-Converting Enzyme 2 Overexpression Remarkably Ameliorated Glomerular Injury in a Rat Model of Diabetic Nephropathy: A Comparison with ACE Inhibition[MolMed: 10_11_liu]
The European Journal of Clinical InvestigationMesangial medium with IgA1 from IgA nephropathy inhibits nephrin expression in mouse podocytes[Wiley: source]
Immunopharmacology and InflammationEvidence for the complementary and synergistic effects of the three-alkaloid combination regimen containing berberine, hypaconitine and skimmianine on the ulcerative colitis rats induced by trinitrobenzene-sulfonic acid[ScienceDirect: S0188440910001049]
NephrologyEffect of aggregated immunoglobulin A1 from immunoglobulin A nephropathy patients on nephrin expression in podocytes[Wiley: source]
PLoS OneAngiotensin II and Angiotensin-(1-7) in Paraventricular Nucleus Modulate Cardiac Sympathetic Afferent Reflex in Renovascular Hypertensive Rats[PubMed: PMC3527547]
BioMed Research InternationalHeterogeneous Downregulation of Angiotensin II AT1-A and AT1-B Receptors in Arterioles in STZ-Induced Diabetic Rat Kidneys[Hindawi: 947506]
34Biglcan is beneficial in angiotensin II induced heart failure by preventing cardiac inflammation and remodeling improving LV function and mortality by preventing transdifferentiation of myofibroblasts[Oxfordjournals: Source]
Pflügers Archiv-European Journal of PhysiologySOD1 gene transfer into paraventricular nucleus attenuates hypertension and sympathetic activity in spontaneously hypertensive rats[Pubmed: 23114721]
Eur J Pharmacol. Angiotensin II and vasopressin are involved in the defense system against anaphylactic hypotension in anesthetized rats[Pubmed:24650734]
J Mol Cell Cardiol.Increased LDL electronegativity in chronic kidney disease disrupts calcium homeostasis resulting in cardiac dysfunction[Pubmed:25871829]
Mol Med Rep.High glucose induces activation of the local renin?angiotensin system in glomerular endothelial cells[Pubmed:24337709]
Mol Med Rep.Angiotensin II promotes the progression of human gastric cancer[Pubmed:24424956]
PLOS ONEIntermedin in the Paraventricular Nucleus Attenuates Cardiac Sympathetic Afferent Reflex in Chronic Heart Failure Rats[Pubmed:24709972]
Journal of Vascular SurgeryCathepsin G deficiency reduces periaortic calcium chloride injury-induced abdominal aortic aneurysms in mice [Pubmed:25037606]
Biochim Biophys Acta. Cathepsin G activity lowers plasma LDL and reduces atherosclerosis[Pubmed:25092171]
Acta PhysiologicaSuperoxide anions in the paraventricular nucleus mediate cardiac sympathetic afferent reflex in insulin resistance rats[Pubmed:25307720]
Neuroscience LettersAdministration of exogenous 1,25(OH)2D3 normalizes overactivation of the central renin-angiotensin system in 1α(OH)ase knockout mice[Pubmed:25576706]
34A background Ca2+ entry pathway mediated by TRPC1/TRPC4 is critical for development of pathological cardiac remodelling[PubMed: 26069213]
Life SciCardioprotective effects of baicalein on heart failure via modulation of Ca2[PubMed: 26706290]
Physiological ResearchRenal Sympathetic Denervation Improves Cardiac Dysfunction[PubMed: 25804096]
NutritionEffects of Rubus occidentalis extract on blood pressure in subjects with prehypertension: randomized, double-blinded, placebo controlled clinical trial[PubMed: 26740254]
J Am Soc HypertensAngiotensin-(1–7) enhances the effects of angiotensin II on the cardiac sympathetic afferent reflex and sympathetic activity in rostral ventrolateral medulla in renovascular hypertensive rats[PubMed: 26428223]
PLoS One.Up ReCavia (Guinea pig )lation of cystathione γ lyase and Hydrogen Sulphide in the Myocardium Inhibits the Progression of Isoproterenol–Caffeine Induced Left Ventricular Hypertrophy in Wistar Kyoto Rats[Pubmed:26963622]
NutritionEffects of Rubus occidentalis extract on blood pressure in patients with prehypertension: Randomized, double-blinded, placebo-controlled clinical trial[Pubmed:26740254]
Journal of Atherosclerosis and ThrombosisInvolvement of Angiotensin II Type 1 and 2 Receptors in Gelatinase ReCavia (Guinea pig )lation in Human Carotid Atheroma in vitro[Pubmed:26947595]
Mol NeurobiolA Therapeutic Insight of Niacin and Coenzyme Q10 Against Diabetic Encephalopathy in Rats[Pubmed:26867655]
Life SciCardioprotective effects of baicalein on heart failure via modulation of Ca(2+) handling proteins in vivo and in vitro[Pubmed:26706290]
PLoS One. Paradoxical Sleep Deprivation Causes Cardiac Dysfunction and the Impairment Is Attenuated by Resistance Training.[pubmed:27880816]
Oxidative Medicine and Cellular LongevityEpigallocatechin-3-gallate Attenuates Renal Damage by Suppressing Oxidative Stress in Diabetic db/db Mice[pubmed:27698952]
Journal of the Renin-Angiotensin-Aldosterone SystemAngiotensin type 2 receptor null mice express reduced levels of renal angiotensin converting enzyme-2/angiotensin (1-7)/Mas receptor and exhibit greater high-fat diet-induced kidney injury[1470320316661871.abstract]
Microvascular ResearchPleiotropic effects of survivin in vascular endothelial cells.[pubmed:27373518]
PLOS ONEReduced Expression of the Extracellular Calcium-Sensing Receptor (CaSR) Is Associated withActivation of the Renin-Angiotensin System (RAS) to Promote Vascular Remodeling in the Pathogenesis of Essential Hypertension.[pubmed:27391973]
journal of pharmacological sciencesβ-Aminoisobutyric acid ameliorates the renal fibrosis in mouse obstructed kidneys via inhibitionof renal fibroblast activation and fibrosis.[pubmed:28433566]
Experimental AnimalsGinsenoside Rb1 improves cardiac function and remodeling in heart failure.[pubmed:28367863]
OncotargetEffects of renal denervation on monocrotaline induced pulmonary remodeling[pubmed:28187460]
The American Journal of PathologyThe Renin-Angiotensin System Regulates Neurodegeneration in a Mouse Model of Optic Neuritis[pubmed:28919108]
PLoS OneEnhanced heart failure, mortality and renin activation in female mice with experimental dilated cardiomyopathy[pubmed:29240788]
Frontiers in PhysiologyHydrogen Sulfide Attenuates Atherosclerosis in a Partially Ligated Carotid Artery Mouse model via Regulating Angiotensin Converting Enzyme 2 Expression[pubmed:29066981]
NeurotherapeuticsBrain Renin–Angiotensin System Blockade Attenuates Methamphetamine-Induced Hyperlocomotion and Neurotoxicity[Pubmed:29464572]
International Journal of CardiologyALDH2 protects against alcoholic cardiomyopathy through a mechanism involving the p38 MAPK/CREB pathway and local renin-angiotensin system inhibition in …[Pubmed:29506687]
NeuroscienceAngiotensin II Type 1a Receptors in the Subfornical Organ Modulate Neuroinflammation in the Hypothalamic Paraventricular Nucleus in Heart Failure Rats[Pubmed:29684507]
American Journal of Physiology-Renal PhysiologyRole of (Pro) Renin Receptor in Albumin Overload-Induced Nephropathy in Rats[Pubmed:29846109]
Journal of the American Society of HypertensionMesenchymal stem cell–derived microvesicles alleviate pulmonary arterial hypertension by regulating renin-angiotensin system[Pubmed:29752040]
Evidence-based Complementary and Alternative Medicine Acute Biochemical, Cardiovascular, and Autonomic Response to Hyperbaric (4 atm) Exposure in Healthy Subjects[Pubmed:29977313]
Brazilian Journal of Medical and Biological ResearchRenovascular hypertension increases serum TNF and CX3CL1 in experimental Trypanosoma cruzi infection[Pubmed:29590257]
American Journal of Physiology-Heart and Circulatory PhysiologySex Differences in the Central and Peripheral Manifestations of Ischemia-induced Heart Failure in Rats[Pubmed: 30289294]
Toxicology Mechanisms and MethodsLong-term exposure to crotonaldehyde causes heart and kidney dysfunction through induction of inflammatory and oxidative damage in male Wistar rats[Pubmed: 30426860]
Journal of Clinical and Aesthetic DermatologyDetection of Angiotensin II and AT1 Receptor Concentrations in Keloid and Hypertrophic Scar.[]
International Journal of OphthalmologySerum microRNA-221 as a biomarker for diabetic retinopathy in patients associated with type 2 diabetes[Pubmed: 30588418]
JOURNAL OF STRENGTH AND CONDITIONING RESEARCHACE Gene Plays a Key Role in Reducing Blood Pressure in The Hyperintensive Elderly After Resistance Training[Pubmed: 30908459]
The American Journal of the Medical SciencesT lymphocyte-based renin angiotensin system in obesity[]
Journal of Alzheimers DiseaseCerebrospinal Fluid Changes in the Renin-Angiotensin System in Alzheimer's Disease[Pubmed: 31594235]
AndrologiaSeminal levels of angiotensin II and angiotensin II type 2 receptor expression on spermatozoa in varicocele patients: Relation to fertility status[Pubmed: 31989676]
Molecular Medicine ReportsBPA disrupts 17‑estradiol‑mediated hepatic protection against ischemia/reperfusion injury in rat liver by upregulating the Ang II/AT1R signaling pathway[Pubmed: 32319667]
MOLECULAR MEDICINE REPORTSThe sympathetic transmitter norepinephrine inhibits VSMC proliferation induced by TGFβ by suppressing the expression of the TGFβ receptor ALK5 in aorta …[Pubmed: 32319652]
Cell Mol NeurobiolPredator Scent-Induced Sensitization of Hypertension and Anxiety-like Behaviors[Pubmed: 33201417]
biochemistry biophysical reportsEffect of repetitive potassium iodide on thyroid and cardiovascular functions in elderly rats[Pubmed: 33024842]
bioscience reportsAngiotensin II enhances the proliferation of Natural Killer/T-cell lymphoma cells via activating PI3K/Akt signaling pathway[Pubmed: 32969473]
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGYA (pro) renin receptor decoy peptide PRO20 protects against adriamycin-induced nephropathy by targeting intrarenal renin-angiotensin system[Pubmed: 32865014]
Acta Endocrinologica-BucharestTHE ROLE OF HIGH FOLLICULAR LEVELS OF ANGIOTENSIN II AND VASCULAR ENDOTHELIAL GROWTH FACTOR IN ANTICIPATING THE …[Pubmed: 32685035]
JOURNAL OF PROTEOME RESEARCHProteomics and informatics for understanding phases and identifying biomarkers in COVID-19 disease[Pubmed: 32657586]
Scientific ReportsIntegrated metabolomics and gut microbiome to the effects and mechanisms of naoxintong capsule on type 2 diabetes in rats[Pubmed: 32616735]
BIOMEDICINE & PHARMACOTHERAPYSemen Brassicae reduces thoracic aortic remodeling, inflammation, and oxidative damage in spontaneously hypertensive rats[Pubmed: 32570115]
CLINICAL AND EXPERIMENTAL HYPERTENSIONHyperinsulinemia rather than insulin resistance itself induces blood pressure elevation in high fat diet-fed rats[Pubmed: 32349626]
Evidence-Based Complementary and Alternative MedicineTianma Gouteng Decoction Exerts Cardiovascular Protection by Upregulating OPG and TRAIL in Spontaneously Hypertensive Rats[Pubmed: 33133215]
Oxidative Medicine and Cellular LongevitySinapic Acid Attenuates Cardiovascular Disorders in Rats by Modulating Reactive Oxygen Species and Angiotensin Receptor Expression[Pubmed: 32765804]
NutritionGut Dysbiosis Contribute to High Fructose Induced Salt Sensitive Hypertension In Sprague-Dawley Rats[]
Dikkat Eksikliği Hiperaktivite Bozukluğu Tanısı Olan Anjiyotensin I, II, III, Alamandin peptid, Anjiyotensin Dönüştürücü Enzim (ACE), NADPH Oksidaz Enzim Serum …[]
Physiol BehavLow-load resistance training with blood flow restriction prevent renal function decline: The role of the redox balance, angiotensin 1-7 and vasopressin[33340514]
ACTA PHARMACOLOGICA SINICAThe vascular endothelial growth factor trap aflibercept induces vascular dysfunction and hypertension via attenuation of eNOS/NO signaling in mice[33303990]
Int J HypertensThe Effects of Renal Nerve Denervation on Blood Pressure and Target Organs in Different Hypertensive Rat Models[33884205]
Physiol Rep(Pro) renin receptor antagonist PRO20 attenuates nephrectomy©\induced nephropathy in rats via inhibition of intrarenal RAS and Wnt/¦Â©\catenin signaling[34057312]
Redox BiologyRenovascular effects of inorganic nitrate following ischemia-reperfusion of the kidney[33360353]
Basic and Clinical NeurosciencePaeonol Protects Against Intrastriatal 6-Hydroxydopamine Rat Model of Parkinson's Disease[33995926]
researchsquareAng-(1-7) Protects Skeletal Muscle Function in Aged Mice[]
Molecular Medicine ReportsLycium barbarum polysaccharides attenuate cardiovascular oxidative stress injury by enhancing the Keap1/Nrf2 signaling pathway in exhaustive exercise rats[34278476]
BMC Musculoskeletal DisordersAng-(1–7) protects skeletal muscle function in aged mice[34548056]
J Am Heart AssocMaternal Angiotensin II–Induced Hypertension Sensitizes Postweaning High‐Fat Diet–Elicited Hypertensive Response Through Increased Brain Reactivity in Rat …[34482712]
Biomed PharmacotherTianma Gouteng Decoction regulates oxidative stress and inflammation in AngII-induced hypertensive mice via transcription factor EB to exert anti …[34736077]
J Am Heart AssocLoss of the Protective Effect of Estrogen Contributes to Maternal Gestational Hypertension‐Induced Hypertensive Response Sensitization Elicited by Postweaning …[Pubmed:35014859]
J Gerontol A Biol Sci Med SciDysregulation of ACE-1 in normal aging and the early stages of Alzheimer's disease[Pubmed:35396835]
Biomedicine & PharmacotherapyCorynoline protects ang II-induced hypertensive heart failure by increasing PPARα and Inhibiting NF-κB pathway[Pubmed:35658238]