Ⅰ型胶原交联羧基端肽(CTXI)单克隆抗体

Monoclonal Antibody to Cross Linked C-Telopeptide Of Type I Collagen (CTXI)

CTX-I; CTX1;

  • Ⅰ型胶原交联羧基端肽(CTXI)单克隆抗体产品包装(模拟)
  • Ⅰ型胶原交联羧基端肽(CTXI)单克隆抗体产品包装(模拟)
  • Ⅰ型胶原交联羧基端肽(CTXI)单克隆抗体DAB staining on IHC-P; Sample: Human Liver Tissue; Primary Ab: 20µg/ml Mouse Anti-Multi-species CTXI Antibody Second Ab: 2µg/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody (Catalog: SAA544Mu19)
  • Ⅰ型胶原交联羧基端肽(CTXI)单克隆抗体DAB staining on IHC-P;
    Sample: Human Liver cancer Tissue;
    Primary Ab: 20µg/ml Mouse Anti-Multi-species CTXI Antibody
    Second Ab: 2µg/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody
    (Catalog: SAA544Mu19)
  • Ⅰ型胶原交联羧基端肽(CTXI)单克隆抗体DAB staining on IHC-P;
    Sample: Human Stomach Tissue;
    Primary Ab: 20µg/ml Mouse Anti-Multi-species CTXI Antibody
    Second Ab: 2µg/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody
    (Catalog: SAA544Mu19)
  • Ⅰ型胶原交联羧基端肽(CTXI)单克隆抗体DAB staining on IHC-P;
    Sample: Human Stomach cancer Tissue;
    Primary Ab: 20µg/ml Mouse Anti-Multi-species CTXI Antibody
    Second Ab: 2µg/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody
    (Catalog: SAA544Mu19)
  • Ⅰ型胶原交联羧基端肽(CTXI)单克隆抗体AF488 staining on IF;
    Sample: U2OS cell
    Primary Ab: 20µg/ml Mouse Anti-Multi-species CTXI Antibody
    Second Ab: 2μg/ml AF488-Linked Caprine Anti-Mouse IgG Polyclonal Antibody
    (Catalog: SAA544Mu11)
  • Certificate通过ISO 9001、ISO 13485质量体系认证

特异性

该抗体是针对CTXI的小鼠单克隆抗体。在免疫组织化学染色和免疫印迹实验中能识别CTXI。

用法

Western blotting: 0.5-2µg/mL;
Immunohistochemistry: 5-20µg/mL;
Immunocytochemistry: 5-20µg/mL;
Optimal working dilutions must be determined by end user.

储存

经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。

稳定性

热稳定性以损失率显示。损失率是由加速降解试验决定,具体方法如下:在37°C孵育48小时,没有显著的降解或者沉淀产生。保质期内,在适当的条件下存储,损失率低于5%。

赠品

相关产品

编号适用物种:Homo sapiens (Human,人)应用(仅供研究使用,不用于临床诊断!)
MAA665Mi21Ⅰ型胶原交联羧基端肽(CTXI)单克隆抗体WB; IHC; ICC; IP.
MAA665Mi28Ⅰ型胶原交联羧基端肽(CTXI)单克隆抗体WB; IHC; ICC; IP.
MAA665Mi26Ⅰ型胶原交联羧基端肽(CTXI)单克隆抗体WB; IHC; ICC; IP.
MAA665Mi27Ⅰ型胶原交联羧基端肽(CTXI)单克隆抗体WB; IHC; ICC; IP.
MAA665Mi22Ⅰ型胶原交联羧基端肽(CTXI)单克隆抗体IHC; ICC/IF
MAA665Mi23Ⅰ型胶原交联羧基端肽(CTXI)单克隆抗体WB; IHC; ICC; IP.
MAA665Mi24Ⅰ型胶原交联羧基端肽(CTXI)单克隆抗体WB; IHC; ICC; IP.
MAA665Mi25Ⅰ型胶原交联羧基端肽(CTXI)单克隆抗体IHC

参考文献

杂志参考文献
journal of bone and mineral researchAtp6v0d2 Is an Essential Component of the Osteoclast-Specific Proton Pump That Mediates Extracellular Acidification in Bone Resorption[PubMed: PMC2672205]
BoneBorage and fish oils lifelong supplementation decreases inflammation and improves bone health in a murine model of senile osteoporosis[PubMed: 21664309]
TrialsIs there benefit in optimising heart failure treatment in over-80 year-old patients? (HF-80 study): study protocol for a randomized controlled trial.[Trials: 1745-6215]
Journal of Biological ChemistryTRAF family member-associated NF-κB activator (TANK) is a negative regulator of osteoclastogenesis and bone formation[PubMed: 22773835]
The Journal of Clinical Endocrinology & MetabolismA Mediterranean Diet Enriched with Olive Oil Is Associated with Higher Serum Total Osteocalcin Levels in Elderly Men at High Cardiovascular Risk[PubMed: PMC3462931]
EndocrinologyOxytocin Reverses Ovariectomy-Induced Osteopenia and Body Fat Gain[Endocrine: Source]
Am J Physiol Endocrinol Metab. DPP IV inhibitor treatment attenuates bone loss and improves mechanical bone strength in male diabetic rats[Pubmed:25053403]
The American Journal of CardiologyRelation of burden of myocardial fibrosis to malignant ventricular arrhythmias and outcomes in Fabry disease[Pubmed:25073565]
Rheumatology (Oxford). Bone resorption correlates with the frequency of CD5+ B cells in the blood of patients with rheumatoid arthritis[Pubmed:25193807]
XPO1/CRM1-Selective Inhibitors of Nuclear Export (SINE) reduce tumor spreading and improve overall survival in preclinical models of prostate cancer (PCa)[Pubmed:25284315]
Rheumatology International The presence of FCGR2B promoter or transmembrane region variant alleles leads to reduced serum IL-6 levels in rheumatoid arthritis[Pubmed:25630523]
The Journal of Biological Chemistry5-azacytidine-induced protein 2 (AZI2) regulates bone mass by fine-tuning osteoclast survival[Pubmed:25691576]
Scandinavian Journal of Clinical and Laboratory InvestigationOsteocartilaginous metabolic markers change over a 3-week stage race in pro-cyclists[PubMed: 26174975]
AIDSEffects of renal tubular dysfunction on bone in tenofovir-exposed HIV-positive patients[PubMed: 26372384]
the journal of rheumatologyBiomarkers in Remission According to Different Criteria in Patients with Rheumatoid Arthritis[PubMed: 26472417]
Int J Mol MedCurcumin alleviates glucocorticoid-induced osteoporosis through the regulation of the Wnt signaling pathway[PubMed: 26677102]
the journal of biological chemistryMutation in Osteoactivin Promotes RANKL-Mediated Osteoclast Differentiation and Survival, but Inhibits Osteoclast Function[PubMed: 25837253]
frontiers in endocrinologyOxytocin reverses osteoporosis in a sex-dependent manner[PubMed: 26042090]
PLoS One. The RIP1–RIP3 Complex Mediates Osteocyte Necroptosis after Ovariectomy in Rats[pmc:PMC4795547]
J Cell PhysiolLanthanum Chloride Attenuates Osteoclast Formation and Function Via the DownreCavia (Guinea pig )lation of Rankl-Induced Nf-κb and Nfatc1 Activities[Pubmed:26060084]
FASEB JournalN-Homocysteinylation impairs collagen cross-linking in cystathionine β-synthase-deficient mice: a novel mechanism of connective tissue abnormalities.[pubmed:27530978]
Metabolism. High FGF21 levels are associated with altered bone homeostasis in HIV-1-infected patients.[pubmed:28521869]
journal of science and medicine in sport The effect of calcium and vitamin D supplementation on bone health of male Jockeys.[pubmed:27568072]
Chemico-Biological InteractionsGinsenosides Rg3 attenuates glucocorticoid-induced osteoporosis through regulating BMP-2/BMPR1A/Runx2 signaling pathway[pubmed:27387537]
Epilepsy ResearchThe effect of lamotrigine and phenytoin on bone turnover and bone strength: A prospective study in Wistar rats[pubmed:27838501]
BoneReduced femoral bone mass in both diet-induced and genetic hyperlipidemia mice[pubmed:27669658]
Journal of Vascular SurgeryA potential role for glycated cross-links in abdominal aortic aneurysm disease.[pubmed:27624703]
Institute of PharmacologyEffects of long-term administration of pantoprazole on bone mineral density in young male rats.[pubmed:27552060]
Biomedicine & PharmacotherapyAnti-osteoporotic effects of an antidepressant tianeptine on ovariectomized rats[S0753332216322752]
European Journal of PharmacologyCannabidiol administration reduces sublesional cancellous bone loss in rats with severe spinal cord injury[pubmed:28479140]
APPLIED SPECTROSCOPYSide-Effects of Convulsive Seizures and Anti-Seizure Therapy on Bone in a Rat Model of Epilepsy[pubmed:28905646]
Clinical NutritionObesity status influences the relationship among serum osteocalcin, iron stores and insulin sensitivity[pubmed:29050649]
OncotargetA novel osteoporosis model with ascorbic acid deficiency in Akr1A1 gene knockout mice.[pubmed:28060768]
中国骨质疏松杂志骨形成指标PINP 与骨吸收指标β-CTX 在2 型糖尿病合并骨质疏松中作用的研究.[10.3969/j.issn.1006-7108.2017.03.009]
BioMed Research InternationalOptimization of the Time Window of Interest in Ovariectomized Imprinting Control Region Mice for Antiosteoporosis Research[pubmed:29119115]
Cell Death And DifferentiationTSC1 regulates osteoclast podosome organization and bone resorption through mTORC1 and Rac1/Cdc42[Pubmed:29358671]
Journal of Periodontology The role of androgens on periodontal repair in female rats[Pubmed:29683499]
Life SciencesMyricetin ameliorates glucocorticoid-induced osteoporosis through the ERK signaling pathway[Pubmed:29883721]
European Journal of PharmacologyThe effect of levetiracetam on rat bone mineral density, bone structure and biochemical markers of bone metabolism[Pubmed:29428468]
Journal of Clinical DensitometryGeometric and mechanical bone response to a multidisciplinary weight loss intervention in adolescents with obesity: The ADIBOX study[Pubmed:30076009]
PharmacologyEffects of Amlodipine on Bone Metabolism in Orchidectomised Spontaneously Hypertensive Rats[Pubmed:29898457]
Experimental and Therapeutic MedicineLiraglutide exerts a bone‑protective effect in ovariectomized rats with streptozotocin‑induced diabetes by inhibiting osteoclastogenesis[Pubmed:29805533]
Experimental and Therapeutic MedicineCombination therapy with BMP‑2 and psoralen enhances fracture healing in ovariectomized mice[10.3892:etm.2018.6353]
Tumor BiologyDual PI3 K/mTOR inhibition reduces prostate cancer bone engraftment altering tumor-induced bone remodeling[Pubmed:29687745]
SensorsMembrane-Based Microwave-Mediated Electrochemical Immunoassay for the In Vitro, Highly Sensitive Detection of Osteoporosis-Related Biomarkers[Pubmed: 30181433]
Tropical Journal of Pharmaceutical ResearchMollugin attenuates glucocorticoid-induced osteoporosis in rats via Akt/P13K pathway[]
Bone & Joint ResearchTranscriptome analysis of osteoblasts in an ovariectomized mouse model in response to physical exercise[]
Toxicol Ind HealthInfluence of physical training on markers of bone turnover, mechanical properties, morphological alterations, density and mineral contents in the femur of rats exposed …[Pubmed: 30983556]
Journal of Geriatric OncologySerum biomarkers for predicting overall survival and early mortality in older patients with metastatic solid tumors[Pubmed: 30952517]
Scientific ReportsSignificance of the Tks4 scaffold protein in bone tissue homeostasis[]
E The Effects of Ficus Carica Fruit on Bone Markers and Oestrogen Level of Post-Menopausal Osteoporotic Rats[]
Biology OpenOsteocyte TSC1 promotes sclerostin secretion to restrain osteogenesis in mice[Pubmed: 31088250]
Journal of PeriodontologyRole of testosterone and androgen receptor in periodontal disease progression in female rats[Pubmed: 31389012]
Journal of clinical periodontologyBiomarkers of oral inflammation in perinatally HIV‐infected and perinatally HIV exposed, uninfected youth[Pubmed: 31385616]
Bulletin of Experimental Biology and MedicineLaboratory Monitoring of Bone Tissue Remodeling after Augmentation of Impression Intraarticular Fracture with Different Types of Bone Graft[Pubmed: 31630302]
Molecular Therapy-Nucleic AcidsAAV-anti-miR-214 prevents collapse of the femoral head in osteonecrosis by regulating osteoblast and osteoclast activities[Pubmed: 31739209]
International Journal of Environmental Research and Public HealthAlleviating Effect of α-Lipoic Acid and Magnesium on Cadmium-Induced Inflammatory Processes, Oxidative Stress and Bone Metabolism Disorders in Wistar Rats[Pubmed: 31739465]
International journal of molecular sciencesDifferences in Osteoimmunological Biomarkers Predictive of Psoriatic Arthritis among a Large Italian Cohort of Psoriatic Patients[Pubmed: 31717649]
Brazilian Journal of Medical and Biological ResearchBeneficial effects of Cuscuta chinensis extract on glucocorticoid-induced osteoporosis through modulation of RANKL/OPG signals[Pubmed: 31826180]
Journal of Bone and Mineral ResearchBMP9 reduces bone loss in ovariectomized mice by dual regulation of bone remodeling[Pubmed: 31914211]
TheranosticsEDTA-Modified 17β-Estradiol-Laden Upconversion Nanocomposite for Bone-Targeted Hormone Replacement Therapy for Osteoporosis[Pubmed: 32194868]
CellsArticle Dual CXCR4 and E-Selectin Inhibitor, GMI-1359, Shows Anti-Bone Metastatic Effects and Synergizes with Docetaxel in Prostate Cancer Cell Intraosseous …[Pubmed: 31877673]
CellRNA Sensing by Gut Piezo1 Is Essential for Systemic Serotonin Synthesis[Pubmed: 32640190]
Advanced ScienceA Loop‐Based and AGO‐Incorporated Virtual Screening Model Targeting AGO‐Mediated miRNA–mRNA Interactions for Drug Discovery to Rescue Bone Phenotype …[Pubmed: 32670749]
International Medical Journal MalaysiaThe Effects of Ficus Carica Fruit on Bone Markers and Oestrogen Level of Post-Menopausal Osteoporotic Rats.[]
Cells.Dual CXCR4 and E-Selectin Inhibitor, GMI-1359, Shows Anti-Bone Metastatic Effects and Synergizes with Docetaxel in Prostate Cancer Cell Intraosseous …[]
Journal of Orthopaedic TranslationQu Feng Zhi Tong capsule increases mechanical properties of cortical bone in ovariectomized rats[]
Research square4-Hexylresorcinol Inhibits Osteoclastogenesis by Suppressing NF‐κB Signaling Pathway and Reverses Bone Loss in Ovariectomized Mice[]
IIUM Medical Journal MalaysiaThe Effects of Ficus Carica Fruit on Bone Markers and Oestrogen Level of Post-Menopausal Osteoporotic Rats[]
淫羊藿水提物及提取药渣的抗骨质疏松药效比较研究[]
Pamukkale Tıp DergisiPostmenapozal Tip-2 diyabetes mellitus' lu hastalarda osteoporoza bağlı kırık riskinin ve kemik Turnoveri'nin değerlendirilmesi[]
Science AdvancesA biomimetically hierarchical polyetherketoneketone scaffold for osteoporotic bone repair[33310848]
J Bone Miner ResLgr4 promotes aerobic glycolysis and differentiation in osteoblasts via the canonical Wnt/¦Â©\catenin pathway[33950533]
Br J PharmacolAndrographolide prevents bone loss via targeting ERRalpha‐regulated metabolic adaption of osteoclastogenesis[34233019]
PHARMACEUTICAL BIOLOGYEffects of icariin on the fracture healing in young and old rats and its mechanism[34511043]
Evid Based Complement Alternat MedGujiansan Ameliorates Avascular Necrosis of the Femoral Head by Regulating Autophagy via the HIF-1α/BNIP3 Pathway[34512780]
Scandinavian Cardiovascular JournalDual integrin αvβ3 and αvβ5 blockade attenuates cardiac dysfunction by reducing fibrosis in a rat model of doxorubicin-induced cardiomyopathy[34296634]
Chronobiol IntNight shift work and osteoporosis-bone turnover markers among female blue-collar workers in Poland[Pubmed:35139709]
Cell MetabDefects in a liver-bone axis contribute to hepatic osteodystrophy disease progression[Pubmed:35235775]
Cell Death DiscovBMP9 reduces age-related bone loss in mice by inhibiting osteoblast senescence through Smad1-Stat1-P21 axis[Pubmed:35523787]
Experimental and Molecular MedicineFoxf2 represses bone formation via Wnt2b/β-catenin signaling[Pubmed:35668101]
Bioactive MaterialsOsteoporotic bone recovery by a bamboo-structured bioceramic with controlled release of hydroxyapatite nanoparticles[Pubmed:35386445]
Journal of Orthopaedic TranslationPuerarin specifically disrupts osteoclast activation via blocking integrin-β3 Pyk2/Src/Cbl signaling pathway[Pubmed:35228997]
Journal of Orthopaedic TranslationExercised accelerated the production of muscle-derived kynurenic acid in skeletal muscle and alleviated the postmenopausal osteoporosis through the Gpr35 …[]