武汉云克隆科技股份有限公司

Gremlin 1蛋白(GREM1)单克隆抗体

Monoclonal Antibody to Gremlin 1 (GREM1)

PIG2; CKTSF1B1; DAND2; IHG-2; DAND2; DRM; Increased in high glucose protein 2; Cell proliferation-inducing gene 2 protein; Cysteine knot superfamily 1, BMP antagonist 1

  • Gremlin 1蛋白(GREM1)单克隆抗体产品包装(模拟)
  • Gremlin 1蛋白(GREM1)单克隆抗体产品包装(模拟)
  • Gremlin 1蛋白(GREM1)单克隆抗体DAB staining on IHC-P; Sample: Human Kidney Tissue; Primary Ab: 20µg/ml Mouse Anti-Human GREM1 Antibody Second Ab: 2µg/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody (Catalog: SAA544Mu19)
  • Certificate通过ISO 9001、ISO 13485质量体系认证

特异性

该抗体是针对GREM1的小鼠单克隆抗体。在免疫组织化学染色和免疫印迹实验中能识别GREM1。

用法

Western blotting: 0.5-2µg/mL;
Immunohistochemistry: 5-20µg/mL;
Immunocytochemistry: 5-20µg/mL;
Optimal working dilutions must be determined by end user.

储存

经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。

稳定性

热稳定性以损失率显示。损失率是由加速降解试验决定，具体方法如下：在37°C孵育48小时，没有显著的降解或者沉淀产生。保质期内，在适当的条件下存储，损失率低于5%。

赠品

相关产品

编号适用物种：Homo sapiens (Human，人)应用(仅供研究使用，不用于临床诊断！)
APC128Hu02Gremlin 1蛋白(GREM1)活性蛋白Cell culture; Activity Assays.
RPC128Hu01Gremlin 1蛋白(GREM1)重组蛋白Positive Control; Immunogen; SDS-PAGE; WB.
APC128Hu01Gremlin 1蛋白(GREM1)活性蛋白Cell culture; Activity Assays.
RPC128Hu02Gremlin 1蛋白(GREM1)重组蛋白Positive Control; Immunogen; SDS-PAGE; WB.
PAC128Hu01Gremlin 1蛋白(GREM1)多克隆抗体WB; IHC; ICC; IP.
PAC128Hu02Gremlin 1蛋白(GREM1)多克隆抗体WB; IHC; ICC; IP.
LAC128Hu81Gremlin 1蛋白(GREM1)多克隆抗体(异硫氰酸荧光素标记)WB; IHC; ICC; IF.
LAC128Hu71Gremlin 1蛋白(GREM1)多克隆抗体(生物素标记)WB; IHC; ICC.
MAC128Hu21Gremlin 1蛋白(GREM1)单克隆抗体IHC
MAC128Hu23Gremlin 1蛋白(GREM1)单克隆抗体IHC
RAC128Hu21Gremlin 1蛋白(GREM1)重组抗体WB; IF; ICC; IHC; IP; FCM.
MAC128Hu22Gremlin 1蛋白(GREM1)单克隆抗体WB; IHC
SEC128HuGremlin 1蛋白(GREM1)检测试剂盒(酶联免疫吸附试验法)Enzyme-linked immunosorbent assay for Antigen Detection.
LMC128HuGremlin 1蛋白(GREM1)等多因子检测试剂盒(流式荧光发光法)FLIA Kit for Antigen Detection.

参考文献

杂志参考文献
LungIntrinsic BMP Antagonist Gremlin-1 as a Novel Circulating Marker in Pulmonary Arterial Hypertension[PubMed: 25926293]
Tumour BiolOverexpression of Gremlin promotes non-small cell lung cancer progression[PubMed: 26392110]
Int J CardiolTriple head-to-head comparison of fibrotic biomarkers galectin-3, osteopontin and gremlin-1 for long-term prognosis in suspected and proven acute heart failure patients[PubMed: 26539964]
International Journal of CardiologyTriple head-to-head comparison of fibrotic biomarkers galectin-3, osteopontin and gremlin-1 for long-termprognosis in suspected and proven acute heart failure patients[Pubmed:26539964]
American Journal of Respiratory Cell and Molecular BiologyBMPR2 Mutation-independent Mechanisms of Disrupted BMP Signaling in IPAH[Pubmed:27187737]
J RheumatolGREM1 Is a Key ReCavia (Guinea pig )lator of Synoviocyte Hyperplasia and Invasiveness[Pubmed:26834210]
European cells & materialsThe BMP2 variant L51P restores the osteogenic differentiation of human mesenchymal stromal cells in the presence of intervertebral disc cells.[pubmed:28266688]
Sci Rep.Genomic reprograming analysis of the Mesothelial to Mesenchymal Transition identifies biomarkers in peritoneal dialysis patients.[pubmed:28327551]
American Journal of Respiratory Cell and Molecular BiologyBone Morphogenic Protein Type 2 Receptor Mutation-Independent Mechanisms of Disrupted Bone Morphogenetic Protein Signaling in Idiopathic Pulmonary Arterial …[rcmb.2015-0402OC]
Molecular Medicine ReportsGremlin-1 suppression increases BMP-2-induced osteogenesis of human mesenchymal stem cells[pubmed:28260028]
Cellular Haemostasis and PlateletsPlatelets as a novel source of Gremlin-1: Implications for thrombo inflammation[pubmed:27929199]
Scientific ReportsGremlin, A Potential Urinary Biomarker of Anca-Associated Crescentic Glomerulonephritis[Pubmed: 31053735]
International Journal of Molecular SciencesTranscriptomic and Proteomic Analyses Reveal the Potential Mode of Action of Chondrocyte Sheets in Hyaline Cartilage Regeneration[Pubmed: 31878307]
American Journal of Physiology-Cell PhysiologySuppression of microRNA-23a/b-3p delays the development degenerative joint disease by activating Grem1 and TGF-β/Smad signaling pathway[Pubmed: 32186934]
InflammopharmacologyProtective role of microRNA-23a/b-3p inhibition against osteoarthritis through Gremlin1-depenent activation of TGF-β/smad signaling in chondrocytesa[Pubmed:35441352]
Mol CarcinogCAF‐derived exosomes transmitted Gremlin‐1 promotes cancer progression and decreases the sensitivity of hepatoma cells to sorafenib[Pubmed:35638711]