武汉云克隆科技股份有限公司

粘蛋白5B(MUC5B)单克隆抗体

Monoclonal Antibody to Mucin 5 Subtype B (MUC5B)

MUC5-B; MUC9; MG1; Oligomeric Mucus/Gel-Forming; Mucin 5,Subtype B,Tracheobronchial; Cervical mucin; High molecular weight salivary mucin MG1; Sublingual gland mucin

  • 粘蛋白5B(MUC5B)单克隆抗体产品包装(模拟)
  • 粘蛋白5B(MUC5B)单克隆抗体产品包装(模拟)
  • 粘蛋白5B(MUC5B)单克隆抗体AF488 staining on IF;
    Sample: HepG2 cell
    Primary Ab: 30µg/ml Mouse Anti-Human MUC5B Antibody
    Second Ab: 2μg/ml AF488-Linked Caprine Anti-Mouse IgG Polyclonal Antibody
    (Catalog: SAA544Mu11)
  • Certificate通过ISO 9001、ISO 13485质量体系认证

特异性

该抗体是针对MUC5B的小鼠单克隆抗体。在免疫组织化学染色和免疫印迹实验中能识别MUC5B。

用法

Western blotting: 0.01-2µg/mL;
Immunohistochemistry: 5-20µg/mL;
Immunocytochemistry: 5-30µg/mL;
Optimal working dilutions must be determined by end user.

储存

经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。

稳定性

热稳定性以损失率显示。损失率是由加速降解试验决定，具体方法如下：在37°C孵育48小时，没有显著的降解或者沉淀产生。保质期内，在适当的条件下存储，损失率低于5%。

赠品

相关产品

编号适用物种：Homo sapiens (Human，人)应用(仅供研究使用，不用于临床诊断！)
RPA684Hu02粘蛋白5B(MUC5B)重组蛋白Positive Control; Immunogen; SDS-PAGE; WB.
RPA684Hu01粘蛋白5B(MUC5B)重组蛋白Positive Control; Immunogen; SDS-PAGE; WB.
CPA684Hu21粘蛋白5B(MUC5B)卵白蛋白偶联物Immunogen; SDS-PAGE; WB.
PAA684Hu01粘蛋白5B(MUC5B)多克隆抗体WB
PAA684Hu02粘蛋白5B(MUC5B)多克隆抗体WB; IHC; ICC; IP.
LAA684Hu81粘蛋白5B(MUC5B)多克隆抗体(异硫氰酸荧光素标记)WB; IHC; ICC; IF.
LAA684Hu71粘蛋白5B(MUC5B)多克隆抗体(生物素标记)WB; IHC; ICC.
MAA684Hu27粘蛋白5B(MUC5B)单克隆抗体WB; IHC; ICC; IP.
MAA684Hu28粘蛋白5B(MUC5B)单克隆抗体IHC
MAA684Hu21粘蛋白5B(MUC5B)单克隆抗体WB; IHC; ICC; IP.
MAA684Hu22粘蛋白5B(MUC5B)单克隆抗体WB
MAA684Hu23粘蛋白5B(MUC5B)单克隆抗体WB; IHC; ICC; IP.
MAA684Hu24粘蛋白5B(MUC5B)单克隆抗体WB; IHC; ICC; IP.
MAA684Hu25粘蛋白5B(MUC5B)单克隆抗体WB; IHC; ICC; IP.
MAA684Hu29粘蛋白5B(MUC5B)单克隆抗体WB; IHC; ICC; IP.
SEA684Hu粘蛋白5B(MUC5B)检测试剂盒(酶联免疫吸附试验法)Enzyme-linked immunosorbent assay for Antigen Detection.
SCA684Hu粘蛋白5B(MUC5B)检测试剂盒(化学发光免疫分析法)Chemiluminescent immunoassay for Antigen Detection.
LMA684Hu粘蛋白5B(MUC5B)等多因子检测试剂盒(流式荧光发光法)FLIA Kit for Antigen Detection.

参考文献

杂志参考文献
The Journal of Biological ChemistryThe Extracellular Signal-regulated Kinase Mitogen-activated Protein Kinase/Ribosomal S6 Protein Kinase 1 Cascade Phosphorylates cAMP Response Element-binding Protein to Induce MUC5B Gene Expression via D-Prostanoid Receptor Signaling[Jcb: 34199]
The Journal of Biological ChemistryThe ERK MAPK/RSK1 cascade phosphorylates CREB to induce MUC5B gene expression via DP1 receptor signaling[Jcb: 247684]
Respiratory ResearhPyocyanin-induced mucin production is associated with redox modification of FOXA2[PubMed: PMC3765780]
RespirologySecreted mucins and airway bacterial colonization in non-CF bronchiectasis[PubMed: 26172851]
American Thoracic Society International Conference AbstractsMucin Secretion In Asthmatics With Osmotic Airway Hyperresponsiveness[doi:10.1164]
Ann Am Thorac SocAirway Mucin 2 Is Decreased in Patients with Severe Chronic Obstructive Pulmonary Disease with Bacterial Colonization[doi:10.1513]
Секреторно-экссудативная реакция слизистой носа на воздействие холодного воздуха у больных бронхиальной астмой[10.20538/1682-0363-2017-2-146-158]
AllergyTh2 cytokines orchestrate the secretion of MUC 5 AC and MUC 5B in IL‐5 positive chronic rhinosinusitis with nasal polyps[Pubmed:29802623]
European Journal of Pharmacology Salvianolic acid B improves airway hyperresponsiveness by inhibiting MUC5AC overproduction associated with Erk1/2/P38 signaling[Pubmed:29382534]
Japan Society of Immunology & Allergology in Otolaryngologyインフルエンザ菌Phosphorylcholine の表出と中耳ムチンMUC5AC 及びMUC5B 産生への影響[10.5648:jjiao.36.7]
Journal of Investigative MedicineThe characteristics and clinical significance of mucin levels in bronchoalveolar lavage fluid of patients with interstitial lung disease[Pubmed: 30573494]
Mucosal ImmunologyASC and NLRP3 maintain innate immune homeostasis in the airway through an inflammasome-independent mechanism[Pubmed: 31278375]