肌肉生长抑制素(MSTN)单克隆抗体
Monoclonal Antibody to Myostatin (MSTN)
GDF8; Growth Differentiation Factor 8
- 编号MAB653Bo21
- 物种Bos taurus; Bovine (Cattle，牛)相同的名称，不同的物种。
- 来源单抗制备
- 宿主小鼠
- 效价(克隆号)8#
- Ig亚型 IgG2b Kappa
- 纯化方式蛋白A + 蛋白G亲和纯化
- 标记物无标记物
- 免疫原RPB653Bo01-肌肉生长抑制素(MSTN)重组蛋白
- 缓冲液成份磷酸盐缓冲液（pH7.4,含有0.02% NaN3和50%甘油）
- 性状液体
- 浓度1mg/ml
- 且适物种Homo sapiens (Human，人)
- 应用WB; IHC; ICC; IP.
如果抗体需用于流式细胞术，请参见流式抗体。 - 下载英文说明书 中文说明书
- 规格20µl100µl200µl1ml10ml
- 价格¥ 760¥ 1772¥ 2532¥ 6330¥ 25320
- 欲了解实际交易价格和更多情况，请与当地经销商联系!
产品包装(模拟)
产品包装(模拟)
AF488 staining on IF;
Sample: U2OS cell
Primary Ab: 20µg/ml Mouse Anti-Bovine MSTN Antibody
Second Ab: 2μg/ml AF488-Linked Caprine Anti-Mouse IgG Polyclonal Antibody
(Catalog: SAA544Mu11)
Western Blot; Sample: Bovine Tongue lysate
Primary Ab: 0.2µg/ml Mouse Anti-Bovine MSTN Antibody
Second Ab: 0.2μg/ml HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody
(Catalog: SAA544Mu19)
通过ISO 9001、ISO 13485质量体系认证
特异性
该抗体是针对MSTN的小鼠单克隆抗体。在免疫组织化学染色和免疫印迹实验中能识别MSTN。
用法
Western blotting: 0.5-2µg/mL;1:500-2000
Immunohistochemistry: 5-20µg/mL;1:50-200
Immunocytochemistry: 5-20µg/mL;1:50-200
Optimal working dilutions must be determined by end user.
储存
经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。
稳定性
热稳定性以损失率显示。损失率是由加速降解试验决定，具体方法如下：在37°C孵育48小时，没有显著的降解或者沉淀产生。保质期内，在适当的条件下存储，损失率低于5%。
赠品
增值服务
相关产品
| 编号 | 适用物种：Bos taurus; Bovine (Cattle，牛) | 应用(仅供研究使用，不用于临床诊断！) |
| RPB653Bo01 | 肌肉生长抑制素(MSTN)重组蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| PAB653Bo01 | 肌肉生长抑制素(MSTN)多克隆抗体 | WB; IHC; ICC; IP. |
| LAB653Bo81 | 肌肉生长抑制素(MSTN)多克隆抗体(异硫氰酸荧光素标记) | WB; IHC; ICC; IF. |
| LAB653Bo71 | 肌肉生长抑制素(MSTN)多克隆抗体(生物素标记) | WB; IHC; ICC. |
| MAB653Bo21 | 肌肉生长抑制素(MSTN)单克隆抗体 | WB; IHC; ICC; IP. |
参考文献
| 杂志 | 参考文献 |
| Clinical Medicine and Diagnostics | Anti-Myostatin Reduces Bone Mineral Loss in Ovariectomized Rats[Sapub:Source] |
| Nutr Metab (Lond) | Short-term, high-fat diet accelerates disuse atrophy and protein degradation in a muscle-specific manner in mice[PubMed: 26539241] |
| International Journal of Cancer | Tumor inoculation site affects the development of cancer cachexia and muscle wasting[PubMed: 26016447] |
| Connect Tissue Res | Induction of transient tenogenic phenotype of high density cultured human dermal fibroblasts[PubMed: 25748814] |
| PLoS One | Higher Plasma Myostatin Levels in Cor Pulmonale Secondary to Chronic Obstructive Pulmonary Disease[Pubmed:26998756] |
| Calcif Tissue Int. | The Effect of Vibration Treatments Combined with Teriparatide or Strontium Ranelate on Bone Healing and Muscle in Ovariectomized Rats[Pubmed:27272029] |
| Archives of medical research | Irisin and Myostatin Levels in Patients with Graves' Disease.[pubmed:27986127] |
| Calcified Tissue International | Effect of Strontium Ranelate on the Muscle and Vertebrae of Ovariectomized Rats[pubmed:29242963] |
| Scientific Reports | Compensatory anabolic signaling in the sarcopenia of experimental chronic arthritis.[pubmed:28740214] |
| Journal of Animal Science | Fermented corn-soybean meal elevated IGF1 levels in grower-finisher pigs[Pubmed: 30203098] |
| European Journal of Internal Medicine | Predictive value of serum myostatin for the severity and clinical outcome of heart failure[Pubmed: 31056368] |
| J Cell Physiol | Resistance training‐induced muscle hypertrophy is mediated by TGF‐β1‐Smad signaling pathway in male Wistar rats[Pubmed: 31960436] |
| NEPHROLOGY DIALYSIS TRANSPLANTATION | Myostatin and muscle atrophy during chronic kidney disease[Pubmed: 32974666] |
| Oxid Med Cell Longev | Gender-Specific Behaviour in Obesity Stages I-II: Imbalance of Aminothiol Status and Adipomyokine Profile in Subjects with Different Insulin Resistance …[34868459] |