武汉云克隆科技股份有限公司

细胞程序性死亡蛋白1配体1(PDL1)单克隆抗体

Monoclonal Antibody to Programmed Cell Death Protein 1 Ligand 1 (PDL1)

CD274; PDCD1LG1; B7-H; B7H1; PD-L1; PDCD1L1; PDCD1-LG1; Programed Death Ligand 1

  • 细胞程序性死亡蛋白1配体1(PDL1)单克隆抗体产品包装(模拟)
  • 细胞程序性死亡蛋白1配体1(PDL1)单克隆抗体产品包装(模拟)
  • 细胞程序性死亡蛋白1配体1(PDL1)单克隆抗体AF488 staining on IF;
    Sample: Hela cell
    Primary Ab: 20µg/ml Mouse Anti-Human PDCD1LG1 Antibody
    Second Ab: 2μg/ml AF488-Linked Caprine Anti-Mouse IgG Polyclonal Antibody
    (Catalog: SAA544Mu11)
  • Certificate通过ISO 9001、ISO 13485质量体系认证

特异性

该抗体是针对PDL1的小鼠单克隆抗体。在免疫组织化学染色和免疫印迹实验中能识别PDL1。

用法

Western blotting: 0.01-2µg/mL;
Immunohistochemistry: 5-20µg/mL;
Immunocytochemistry: 5-20µg/mL;
Optimal working dilutions must be determined by end user.

储存

经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。

稳定性

热稳定性以损失率显示。损失率是由加速降解试验决定，具体方法如下：在37°C孵育48小时，没有显著的降解或者沉淀产生。保质期内，在适当的条件下存储，损失率低于5%。

赠品

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编号适用物种：Homo sapiens (Human，人)应用(仅供研究使用，不用于临床诊断！)
RPA788Hu02细胞程序性死亡蛋白1配体1(PDL1)重组蛋白Positive Control; Immunogen; SDS-PAGE; WB.
RPA788Hu01细胞程序性死亡蛋白1配体1(PDL1)重组蛋白Positive Control; Immunogen; SDS-PAGE; WB.
APA788Hu61细胞程序性死亡蛋白1配体1(PDL1)活性蛋白Cell culture; Activity Assays.
EPA788Hu61细胞程序性死亡蛋白1配体1(PDL1)真核蛋白Positive Control; Immunogen; SDS-PAGE; WB.
PAA788Hu01细胞程序性死亡蛋白1配体1(PDL1)多克隆抗体WB; ICC/IF
FAA788Hu01抗细胞程序性死亡蛋白1配体1(PDL1)多克隆抗体Flow cytometry.
FAA788Hu41抗细胞程序性死亡蛋白1配体1(PDL1)多克隆抗体(藻红素标记)Flow cytometry.
FAA788Hu51抗细胞程序性死亡蛋白1配体1(PDL1)多克隆抗体(别藻蓝蛋白标记)Flow cytometry.
FAA788Hu81抗细胞程序性死亡蛋白1配体1(PDL1)多克隆抗体(异硫氰酸荧光素标记)Flow cytometry.
MAA788Hu28细胞程序性死亡蛋白1配体1(PDL1)单克隆抗体WB; IHC; ICC; IP.
MAA788Hu22细胞程序性死亡蛋白1配体1(PDL1)单克隆抗体WB; IHC; ICC; IP.
RAA788Hu22细胞程序性死亡蛋白1配体1(PDL1)重组抗体WB; IF; ICC; IHC; IP; FCM.
MAA788Hu21细胞程序性死亡蛋白1配体1(PDL1)单克隆抗体WB; IHC; ICC; IP.
MAA788Hu23细胞程序性死亡蛋白1配体1(PDL1)单克隆抗体WB; IHC; ICC; IP.
MAA788Hu24细胞程序性死亡蛋白1配体1(PDL1)单克隆抗体WB; IHC; ICC; IP.
MAA788Hu25细胞程序性死亡蛋白1配体1(PDL1)单克隆抗体WB; IHC; ICC; IP.
MAA788Hu27细胞程序性死亡蛋白1配体1(PDL1)单克隆抗体WB; IHC; ICC; IP.
MAA788Hu29细胞程序性死亡蛋白1配体1(PDL1)单克隆抗体WB; IHC; ICC; IP.
MAA788Hu26细胞程序性死亡蛋白1配体1(PDL1)单克隆抗体WB; IHC; ICC; IP.
RAA788Hu21细胞程序性死亡蛋白1配体1(PDL1)重组抗体WB; IF; ICC; IHC; IP; FCM.
LAA788Hu72细胞程序性死亡蛋白1配体1(PDL1)单克隆抗体(生物素标记)WB; IHC; ICC.
FAA788Hu82抗细胞程序性死亡蛋白1配体1(PDL1)单克隆抗体(异硫氰酸荧光素标记)Flow cytometry.
WEA788Hu细胞程序性死亡蛋白1配体1(PDL1)检测试剂盒(酶联免疫吸附试验法,宽范围)Enzyme-linked immunosorbent assay for Antigen Detection.
SEA788Hu细胞程序性死亡蛋白1配体1(PDL1)检测试剂盒(酶联免疫吸附试验法)Enzyme-linked immunosorbent assay for Antigen Detection.
SCA788Hu细胞程序性死亡蛋白1配体1(PDL1)检测试剂盒(化学发光免疫分析法)Chemiluminescent immunoassay for Antigen Detection.
LMA788Hu细胞程序性死亡蛋白1配体1(PDL1)等多因子检测试剂盒(流式荧光发光法)FLIA Kit for Antigen Detection.
PSA788Hu01细胞程序性死亡蛋白1配体1(PDL1)抗体对ELISA; CLIA; ELISPOT; Luminex; Immunochromatography and other Immunoassays.
KSA788Hu01细胞程序性死亡蛋白1配体1(PDL1)检测试剂盒DIY材料(酶联免疫吸附试验法)Main materials for "Do It (ELISA Kit) Yourself".

参考文献

杂志参考文献
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Leukemia.?High level of soluble programmed cell death ligand 1 in blood impacts overall survival in aggressive diffuse large B-Cell lymphoma: results from a French multicenter clinical trial.[Pubmed:24732592]
Diabetes?Metab Res Rev.PD‐L1 gene polymorphisms and low serum level of PD‐L1 protein are associated to type 1 diabetes in Chile[Pubmed:24816853]
Lancet HaematolRatios of T-cell immune effectors and checkpoint molecules as prognostic biomarkers in diffuse large B-cell lymphoma: a population-based study[PubMed: 26686046]
Eur J Cancer. High levels of the soluble programmed death-ligand (sPD-L1) identify hepatocellular carcinoma patients with a poor prognosis.[Pubmed:27039170]
Journal of Cancer Research and Clinical OncologySerum levels of soluble programmed cell death ligand 1 as a prognostic factor on the first-line treatment of metastatic or recurrent gastric cancer[article:10.1007]
Journal of Hematology & OncologyPD-L1 is upregulated by EBV-driven LMP1 through NF-κB pathway and correlates with poor prognosis in natural killer/T-cell lymphoma[pubmed:27737703]
Lung Cancer. High plasma levels of soluble programmed cell death ligand 1 are prognostic for reduced survival in advanced lung cancer.[pubmed:28212990]
OncotargetSoluble programmed death-ligand 1 (sPDL1) and neutrophil-to-lymphocyte ratio (NLR) predictssurvival in advanced biliary tract cancer patients treated with palliative chemotherapy.[pubmed:27780932]
OncotargetHigh post-treatment serum levels of soluble programmed cell death ligand 1 predict earlyrelapse and poor prognosis in extranodal NK/T cell lymphoma patients.[pubmed:27105512]
Oncotarget. Soluble PD-L1: A biomarker to predict progression of autologous transplantation in patients with multiple myeloma[pubmed:27566569]
Cancer Immunol Immunother.Programmed death-ligand 1 and its soluble form are highly expressed in nasal natural killer/T-cell lymphoma: a potential rationale for immunotherapy.[pubmed:28349165]
LeukemiaSoluble programmed death-ligand 1 as a prognostic biomarker for overall survival in patients with diffuse large B-cell lymphoma: a replication study and combined analysis of 508 patients[leu2016385a]
MedicinePlasma levels of soluble programmed death ligand-1 may be associated with overall survival in nonsmall cell lung cancer patients receiving thoracic radiotherapy.[pubmed:28207525]
Allergology International Inverse correlation of soluble programmed cell death-1 ligand-1 (sPD-L1) with eosinophil count and clinical severity in allergic rhinitis patients[pubmed:27617656]
MedicinePlasma levels of soluble programmed death ligand-1 may be associated with overall survival in nonsmall cell lung cancer patients receiving thoracic radiotherapy[PMC5319514]
American Journal of Respiratory and Critical Care MedicineSoluble Programed Death Receptor 1 Ligand (sPD-L1) in Pleural Fluid of Patients with Malignant Pleural Mesothelioma (MPM)[Pdf:10.1164]
Clinical Lung CancerSoluble Programmed Cell Death Ligand 1 as a Novel Biomarker for Nivolumab Therapy for Non–Small-cell Lung Cancer[Pubmed:29859759]
Journal of RheumatologyIncreased levels of soluble programmed death ligand 1 associate with malignancy in patients with dermatomyositis[Pubmed:29419471]
Translational OncologyHigh Serum Level of Soluble Programmed Death Ligand 1 is Associated With a Poor Prognosis in Hodgkin Lymphoma[Pubmed:29698935]
Immunology LettersIncreased levels of soluble co-stimulatory molecule PD-L1 (B7-H1) in the plasma of viraemic HIV-1+ individuals[Pubmed: 30236481]
Journal of Cancer Research and Clinical OncologyPre-treatment serum levels of soluble programmed cell death-ligand 1 predict prognosis in patients with hepatitis B-related hepatocellular carcinoma[Pubmed: 30267213]
Annals of Surgical OncologySoluble PD-L1 Expression in Circulation as a Predictive Marker for Recurrence and Prognosis in Gastric Cancer: Direct Comparison of the Clinical Burden Between …[Pubmed: 30565045]
American Journal of Reproductive ImmunologyIdentification of programmed cell death 1 and its ligand in the testicular tissue of mice[Pubmed: 30578744]
PLoS OneClinical significance of soluble programmed cell death-1 and soluble programmed cell death-ligand 1 in patients with locally advanced rectal cancer treated …[Pubmed: 30807610]
Endocrine ConnectionsElevated levels of soluble PD-L1 are associated with reduced recurrence in papillary thyroid cancer[Pubmed: 31252406]
Scientific ReportsPrognostic implications of soluble programmed death-ligand 1 and its dynamics during chemotherapy in unresectable pancreatic cancer[Pubmed: 31366979]
Critical Reviews in Oncology / HematologyThe Clinical Significance of Soluble PD-1 and PD-L1 in Lung Cancer[Pubmed: 31675543]
PLoS OneClinical implications of APOBEC3A and 3B expression in patients with breast cancer[Pubmed: 32176735]
CancersPredictive Value of Soluble PD-1, PD-L1, VEGFA, CD40 Ligand and CD44 for Nivolumab Therapy in Advanced Non-Small Cell Lung Cancer: A Case-Control Study[Pubmed: 32085544]
Serum levels of soluble programmed death-ligand 1 (sPD-L1) in patients with primary central nervous system diffuse large B-cell lymphoma[Pubmed: 32054467]
LIVER INTERNATIONALThe prognostic role of soluble transforming growth factor‐β and its correlation with soluble programmed death‐ligand 1 in biliary tract cancer[Pubmed: 32780918]
CANCER IMMUNOLOGY IMMUNOTHERAPYPrognostic impacts of tumoral expression and serum levels of PD-L1 and CTLA-4 in colorectal cancer patients[Pubmed: 32577816]
Soluble PD-L1: a potential immune marker for HIV-1 infection and virological failure[Pubmed: 32443313]
Cancer Immunol ImmunotherThe clinical implication of soluble PD-L1 (sPD-L1) in patients with breast cancer and its biological function in regulating the function of T lymphocyte[33688997]
Acta Biochim Biophys SinPrognostic prospect of soluble programmed cell death ligand-1 (sPD-L1) in cancer management[34180502]
EMBO JMicroglial PD‐1 stimulation by astrocytic PD‐L1 suppresses neuroinflammation and Alzheimer's disease pathology[34825707]
Mol PharmA Novel Small Cyclic Peptide-Based 68Ga-Radiotracer for Positron Emission Tomography Imaging of PD-L1 Expression in Tumors[34910492]
Mol Hum ReprodMacrophage Associated Immune Checkpoint CD47 Blocking Ameliorates Endometriosis[Pubmed:35404426]
Journal of NanobiotechnologyMicrobial hydrogen “manufactory” for enhanced gas therapy and self-activated immunotherapy via reduced immune escape[Pubmed:35705974]
MedicinaAssessment of the RANTES Level Correlation and Selected Inflammatory and Pro-Angiogenic Molecules Evaluation of Their Influence on CRC Clinical Features: A …[Pubmed:35208526]