武汉云克隆科技股份有限公司

突触核蛋白α(SNCa)单克隆抗体

Monoclonal Antibody to Synuclein Alpha (SNCa)

SNC-A; aSYN; PD1; PARK1; PARK4; NACP; Non-A Beta Component Of Alzheimer's Disease Amyloid Precursor Protein; Non-A4 component of amyloid precursor

  • 突触核蛋白α(SNCa)单克隆抗体产品包装(模拟)
  • 突触核蛋白α(SNCa)单克隆抗体产品包装(模拟)
  • 突触核蛋白α(SNCa)单克隆抗体Western Blot; Sample: Rat Cerebellum lysate
    Primary Ab: 0.2µg/ml Mouse Anti-Mouse SNCa Antibody
    Second Ab: 0.2µg/ml HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody
    (Catalog: SAA544Mu19)
  • Certificate通过ISO 9001、ISO 13485质量体系认证

特异性

该抗体是针对SNCa的小鼠单克隆抗体。在免疫组织化学染色和免疫印迹实验中能识别SNCa。

用法

Western blotting: 0.1-2µg/mL;
Immunohistochemistry: 5-20µg/mL;
Immunocytochemistry: 5-20µg/mL;
Optimal working dilutions must be determined by end user.

储存

经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。

稳定性

热稳定性以损失率显示。损失率是由加速降解试验决定，具体方法如下：在37°C孵育48小时，没有显著的降解或者沉淀产生。保质期内，在适当的条件下存储，损失率低于5%。

赠品

相关产品

编号适用物种：Mus musculus (Mouse，小鼠)应用(仅供研究使用，不用于临床诊断！)
RPB222Mu01突触核蛋白α(SNCa)重组蛋白Positive Control; Immunogen; SDS-PAGE; WB.
RPB222Mu02突触核蛋白α(SNCa)重组蛋白Positive Control; Immunogen; SDS-PAGE; WB.
PAB222Mu02突触核蛋白α(SNCa)多克隆抗体WB; IHC; ICC; IP.
PAB222Mu01突触核蛋白α(SNCa)多克隆抗体WB; IHC; ICC; IP.
MAB222Mu21突触核蛋白α(SNCa)单克隆抗体WB
SEB222Mu突触核蛋白α(SNCa)检测试剂盒(酶联免疫吸附试验法)Enzyme-linked immunosorbent assay for Antigen Detection.
MEB222Mu突触核蛋白α(SNCa)检测试剂盒(酶联免疫吸附试验法,小样本)Enzyme-linked immunosorbent assay for Antigen Detection.
LMB222Mu突触核蛋白α(SNCa)等多因子检测试剂盒(流式荧光发光法)FLIA Kit for Antigen Detection.
KSB222Mu01突触核蛋白α(SNCa)检测试剂盒DIY材料(酶联免疫吸附试验法)Main materials for "Do It (ELISA Kit) Yourself".

参考文献

杂志参考文献
The Journal of Clinical InvestigationCerebrospinal fluid–based kinetic biomarkers of axonal transport in monitoring neurodegeneration[PubMed: PMC3428100]
Neurobiology of DiseaseLysosomal dysfunction increases exosome-mediated alpha-synuclein release and transmission[PubMed: PMC3107939]
Nature CommunicationsParkinson's disease induced pluripotent stem cells with triplication of the α-synuclein locus[PubMed: PMC3265381]
Provisional chapterMutations of PARK Genes and Alpha-Synuclein and Parkin Concentrations in Parkinson’s Disease[Intechopen:Source]
NerodegenerationApolipoprotein Eε4: A Biomarker for Executive Dysfunction among Parkinson's Disease Patients with Mild Cognitive Impairment[pubmed:29326545]
Experimental gerontologyThe anti-aging protein klotho alleviates injury of nigrostriatal dopaminergic pathway in 6-hydroxydopamine rat model of Parkinson's disease: Involvement of PKA/CaMKII/CREB signaling.[pubmed:29107062]
Neurobiology of DiseaseDevelopment and biochemical characterization of a mouse model of Parkinson's disease bearing defective glucocerebrosidase activity[Pubmed: 30521842]
molecular and cellular biochemistryPotential therapeutic effects of antagonizing adenosine A2A receptor, curcumin and niacin in rotenone-induced Parkinson's disease mice model[Pubmed: 31820278]
International Journal of PharmacologyNose to brain delivery of rotigotine loaded chitosan nanoparticles in human SH-SY5Y neuroblastoma cells and animal model of Parkinson's disease[Pubmed: 32084576]
EBioMedicineAnti-α-synuclein ASO delivered to monoamine neurons prevents α-synuclein accumulation in a Parkinson's disease-like mouse model and in monkeys[Pubmed: 32810825]