头蛋白(NOG)重组蛋白
Recombinant Noggin (NOG)
SYM1; SYNS1; Synostoses(Multiple)Syndrome 1; Symphalangism 1(Proximal)
- 编号RPC130Po01
- 物种Sus scrofa; Porcine (Pig，猪)相同的名称，不同的物种。
- 来源原核表达
- 宿主E.coli
- 内毒素水平<1.0EU/µg(LAL法测定)
- 亚细胞定位分泌
- 预测分子量24.3kDa
- 实际分子量27kDa(差异分析请参阅说明书)
- 片段与标签Gln28~Cys232 with N-terminal His Tag
- 缓冲液成份磷酸盐缓冲液（pH7.4，含有 0.01% SKL, 1mM DTT, 5% Trehalose和Proclin300.）
- 性状冻干粉
- 纯度> 95%
- 等电点9.0
- 应用Positive Control; Immunogen; SDS-PAGE; WB.
如果需要有生物活性的蛋白，请参见活性蛋白。 - 下载英文说明书 中文说明书
- 规格10µg50µg200µg1mg5mg
- 价格¥ 1032¥ 2580¥ 5160¥ 15480¥ 38700
- 欲了解实际交易价格和更多情况，请与当地经销商联系!
产品包装(模拟)
产品包装(模拟)
Figure. SDS-PAGE
通过ISO 9001、ISO 13485质量体系认证
序列
用法
Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
储存
避免反复冻融。2-8°C不超过一个月，-80°C不超过12个月。
稳定性
热稳定性以损失率显示。损失率是由加速降解试验决定，具体方法如下：在37°C孵育48小时，没有显著的降解或者沉淀产生。保质期内，在适当的条件下存储，损失率低于5%。
增值服务
相关产品
| 编号 | 适用物种：Sus scrofa; Porcine (Pig，猪) | 应用(仅供研究使用，不用于临床诊断！) |
| RPC130Po01 | 头蛋白(NOG)重组蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| PAC130Po01 | 头蛋白(NOG)多克隆抗体 | WB; IHC; ICC; IP. |
| LAC130Po71 | 头蛋白(NOG)多克隆抗体(生物素标记) | WB; IHC; ICC. |
参考文献
| 杂志 | 参考文献 |
| Arthritis Rheumatol | Imbalance between BMP2 and Noggin induces abnormal osteogenic differentiation of mesenchymal stem cells in ankylosing spondylitis[PubMed: 26413886] |
| Arthritis Rheumatol. | Imbalance Between Bone Morphogenetic Protein 2 and Noggin Induces Abnormal Osteogenic Differentiation of Mesenchymal Stem Cells in Ankylosing Spondylitis[Pubmed:26413886] |
| Clin Exp Pharmacol Physiol. | Oxygen-glucose deprivation preconditioning protects neurons against oxygen-glucose deprivation/reperfusion induced injury via bone morphogenetic protein-7 mediated ERK, p38 and Smad signalling pathways.[Pubmed:26385023] |
| European cells & materials | The BMP2 variant L51P restores the osteogenic differentiation of human mesenchymal stromal cells in the presence of intervertebral disc cells.[pubmed:28266688] |
| Arthritis & Rheumatology | mbalance Between Bone Morphogenetic Protein 2 and Noggin Induces Abnormal OsteogenicDifferentiation of Mesenchymal Stem Cells in Ankylosing Spondylitis.[pubmed:26413886] |
| Biotechnology and Applied Biochemistry | The BMP antagonist Noggin is produced by osteoblasts in response to the presence of prostate cancer cells.[pubmed:28981962] |
| Heliyon | Efficient in vitro delivery of Noggin siRNA enhances osteoblastogenesis[pubmed:29167826] |
| Journal of Cellular Biochemistry | Low‐intensity pulsed ultrasound promotes bone morphogenic protein 9‐induced osteogenesis and suppresses inhibitory effects of inflammatory cytokines on cellular …[Pubmed: 31006911] |
| Aging Male | Effect of tadalafil on penile nitric oxide synthase and corporal smooth muscle in rats under dutasteride treatment[Pubmed: 32160825] |
| J Reconstr Microsurg | Effect of Simvastatin Use in Free Tissue Transfer: An Experimental Study in a Rat Epigastric Free Flap Model[Pubmed: 31995818] |
| Biochem Biophys Rep | Slow diffusion on the monolayer culture enhances auto/paracrine effects of Noggin in differentiation of human iPS cells induced by BMP[Pubmed:35005256] |