激活蛋白C(APC)多克隆抗体
Polyclonal Antibody to Activated Protein C (APC)
- 编号PAA738Ra01
- 物种Rattus norvegicus (Rat，大鼠)相同的名称，不同的物种。
- 来源多抗制备
- 宿主兔
- 效价-
- Ig类型IgG
- 纯化方式抗原特异性亲和纯化
- 标记物无标记物
- 免疫原-
- 缓冲液成份0.01M 磷酸盐缓冲液（pH7.4，containing 0.05% Proclin-300，50% glycerol）
- 性状液体
- 浓度0.5mg/ml
- 且适物种Homo sapiens (Human，人)
- 应用WB; IHC; ICC/IF
如果抗体需用于流式细胞术，请参见流式抗体。 - 下载英文说明书 中文说明书
- 规格20µl100µl200µl1ml10ml
- 价格¥ 810¥ 1890¥ 2700¥ 6750¥ 27000
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产品包装(模拟)
产品包装(模拟)
DAB staining on IHC-P; Samples: Rat Liver Tissue; Primary Ab: 10µg/ml Rabbit Anti-Rat APC Antibody Second Ab: 2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: SAA544Rb19)
AF488 staining on IF;
Sample: K562 cell
Primary Ab: 20µg/ml Rabbit Anti-Rat APC Antibody
Second Ab: 2μg/ml AF488-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
(Catalog: SAA544Rb11)
Western Blot; Sample: Lane1: Rat Serum; Lane2: Rat Plasma Primary Ab: 4µg/ml Rabbit Anti-Rat APC Antibody Second Ab: 0.2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: SAA544Rb19)
通过ISO 9001、ISO 13485质量体系认证
特异性
该抗体是针对APC的兔多克隆抗体。在免疫组织化学染色和免疫印迹实验中能识别APC。
用法
Western blotting: 0.5-2µg/mL
Immunohistochemistry: 5-20µg/mL
Immunocytochemistry: 5-20µg/mL
Optimal working dilutions must be determined by end user.
储存
经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。
稳定性
热稳定性以损失率显示。损失率是由加速降解试验决定，具体方法如下：在37°C孵育48小时，没有显著的降解或者沉淀产生。保质期内，在适当的条件下存储，损失率低于5%。
赠品
相关产品
| 编号 | 适用物种：Rattus norvegicus (Rat，大鼠) | 应用(仅供研究使用，不用于临床诊断！) |
| PAA738Ra01 | 激活蛋白C(APC)多克隆抗体 | WB; IHC; ICC/IF |
| SEA738Ra | 激活蛋白C(APC)检测试剂盒(酶联免疫吸附试验法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| LMA738Ra | 激活蛋白C(APC)等多因子检测试剂盒(流式荧光发光法) | FLIA Kit for Antigen Detection. |
参考文献
| 杂志 | 参考文献 |
| The Journal of Immunology | Activated Protein C Attenuates Systemic Lupus Erythematosus and Lupus Nephritis in MRL-Fas(lpr) Mice[Jimmunol: 3413] |
| Critical Care | Disseminated intravascular coagulation or acute coagulopathy of trauma shock early after trauma? An observational study[BioMed: cc10553] |
| Molecular Endocrinology | Intraovarian Thrombin and Activated Protein C Signaling System Regulates Steroidogenesis during the Periovulatory Period[Endo: source] |
| Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine | High levels of soluble VEGF receptor 1 early after trauma are associated with shock, sympathoadrenal activation, glycocalyx degradation and inflammation in severely injured patients: a prospective study[Sjtrem:1757-7241] |
| Crit Care. | Impact of plasma histones in human sepsis and their contribution to cellular injury and inflammation[Pubmed:25260379] |
| Am J Physiol Heart Circ Physiol. | Monocytes regulate systemic coagulation and inflammation in abdominal sepsis[Pubmed:25502108] |
| Neuroscience | Protective effects of thrombomodulin on microvascular permeability after subarachnoid hemorrhage in mouse model[PubMed: 25936678] |
| Journal of Intensive Care | Activated protein C does not increase in the early phase of trauma with disseminated intravascular coaCavia (Guinea pig )lation: comparison with acute coaCavia (Guinea pig )lopathy of trauma-shock[Pubmed:26734467] |
| Journal of Biological Chemistry | Brain microvascular endothelial cells exhibit lower activation of the alternative complement pathway than glomerular microvascular endothelial cells.[JBC:Source] |
| J Thromb Haemost | A multicenter prospective validation study on disseminated intravascular coagulation in trauma‐induced coagulopathy[Pubmed: 32480432] |
| Validation of the Relationship Between Coagulopathy and Localization of Hydroxyethyl Starch on the Vascular Endothelium in a Rat Hemodilution Model[34021192] |