Ⅰ型前胶原羧基端原肽(PICP)多克隆抗体

Polyclonal Antibody to Procollagen I C-Terminal Propeptide (PICP)

P1CP; C-Propeptide Of Type I Procollagen; Procollagen I Carboxy Terminal Propeptide

特异性

该抗体是针对PICP的兔多克隆抗体。在免疫组织化学染色和免疫印迹实验中能识别PICP。

用法

Western blotting: 0.01-2µg/mL;
Immunohistochemistry: 5-20µg/mL;
Immunocytochemistry: 5-20µg/mL;
Optimal working dilutions must be determined by end user.

储存

经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。

稳定性

热稳定性以损失率显示。损失率是由加速降解试验决定,具体方法如下:在37°C孵育48小时,没有显著的降解或者沉淀产生。保质期内,在适当的条件下存储,损失率低于5%。

赠品

相关产品

编号适用物种:Homo sapiens (Human,人)应用(仅供研究使用,不用于临床诊断!)
RPA570Hu01Ⅰ型前胶原羧基端原肽(PICP)重组蛋白Positive Control; Immunogen; SDS-PAGE; WB.
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APA570Hu61Ⅰ型前胶原羧基端原肽(PICP)活性蛋白Cell culture; Activity Assays.
CPA570Hu22Ⅰ型前胶原羧基端原肽(PICP)卵白蛋白偶联物Immunogen; SDS-PAGE; WB.
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PAA570Hu01Ⅰ型前胶原羧基端原肽(PICP)多克隆抗体WB; IHC; ICC; IP.
PAA570Hu08Ⅰ型前胶原羧基端原肽(PICP)多克隆抗体WB; IHC; ICC; IP.
SEA570HuⅠ型前胶原羧基端原肽(PICP)检测试剂盒(酶联免疫吸附试验法)Enzyme-linked immunosorbent assay for Antigen Detection.
SCA570HuⅠ型前胶原羧基端原肽(PICP)检测试剂盒(化学发光免疫分析法)Chemiluminescent immunoassay for Antigen Detection.
LMA570HuⅠ型前胶原羧基端原肽(PICP)等多因子检测试剂盒(流式荧光发光法)FLIA Kit for Antigen Detection.

参考文献

杂志参考文献
NutritionDyslipidemic high-fat diet affects adversely bone metabolism in mice associated with impaired antioxidant capacity[ScienceDirect: S0899900709004717]
American Heart Journal Serum markers of deranged myocardial collagen turnover: their relation to malignant ventricular arrhythmias in cardioverter-defibrillator recipients with heart failure.[PubMed: 23067911]
Journal of HypertensionCirculating biomarkers of collagen metabolism in arterial hypertension: relevance of target organ damage[Pubmed: 23615327]
PancreatologyCdkn1a is a key mediator of rat pancreatic stellate cell senescence[Pubmed: 23719597]
The American Journal of CardiologyRelation of burden of myocardial fibrosis to malignant ventricular arrhythmias and outcomes in Fabry disease[Pubmed:25073565]
PLoS One. An NMR Metabolomic Study on the Effect of Alendronate in Ovariectomized Mice[Pubmed:25184758]
Journal of Bone and Mineral ResearchThe Anti-Osteoanabolic Function of Sclerostin is Blunted in Mice Carrying a High Bone Mass Mutation of Lrp5[Pubmed:25640331]
BoneThe active role of osteoporosis in the interaction between osteoblasts and bone metastases[PubMed: 26057367]
J Nutr BiochemConsumption of vitamin D2[PubMed: 25792284]
Bibliothekssystem Universität HamburgBilaterale Kommunikation zwischen Osteoblasten und Osteoklasten[volltexte:2016]
Inflammation ResearchFibrosis of extracellular matrix is related to the duration of the disease but is unrelated to the dynamics of collagen metabolism in dilated cardiomyopathy[pubmed:27516211]
Heart & VesselsLeft ventricular reverse remodeling is not related to biopsy-detected extracellular matrix fibrosis and serum markers of fibrosis in dilated cardiomyopathy, regardless of the definition used for LVRR[pubmed:28004175]
Scandinavian Journal of RheumatologyThe association between insulin-like growth factor 1 (IGF-1), IGF-binding proteins (IGFBPs), and the carboxyterminal propeptide of type I procollagen (PICP) in pre- and postmenopausal women with rheumatoid arthritis.[pubmed:27775453]
Allergy and Asthma ProceedingsEffect of montelukast on markers of airway remodeling in children withasthma.[pubmed:27657514]
Scandinavian Journal of Rheumatology The association between insulin-like growth factor 1 (IGF-1), IGF-binding proteins (IGFBPs), and the carboxyterminal propeptide of type I procollagen (PICP) in pre- and postmenopausal women with rheumatoid arthritis[loi:irhe20]
Conditional Mouse Models Support the Role of SLC39A14 (ZIP14) in Hyperostosis Cranialis Interna and in Bone Homeostasis[ISBN: 978-94-6299-582-6]
MOLECULAR MEDICINE REPORTS Endothelial‑to‑mesenchymal transition in human idiopathic dilated cardiomyopathy[pubmed:29115553]
Pediatrics and NeonatologyAge-related changes in biochemical bone profile in thalassemic children[pubmed:28967496]
Heart and VesselsLeft ventricular reverse remodeling is not related to biopsy‑detected extracellular matrix fibrosis and serum markers of fibrosis in dilated cardiomyopathy, regardless of the definition used for LVRR[10.1007/s00380-016-0930-y]
Journal of Bone and Mineral ResearchThe Lrp4 R1170Q homozygous knock‐in mouse recapitulates the bone phenotype of sclerosteosis in humans[pubmed:28477420]
Cytokine12-month patterns of serum markers of collagen synthesis, transforming growth factor and connective tissue growth factor are similar in new-onset and chronic dilated cardiomyopathy in patients both with and without cardiac fibrosis.[pubmed:28460256]
Advanced Healthcare MaterialsPrognostic value of fibrosis-related markers in dilated cardiomyopathy: A link between osteopontin and cardiovascular events.[pubmed:29120858]
Journal of Bone and Mineral MetabolismMutations That Alter the Carboxy‐Terminal‐Propeptide Cleavage Site of the Chains of Type I Procollagen Are Associated With a Unique Osteogenesis Imperfecta …[Pubmed:29669177]
Cardiovascular Journal of AfricaAssessment of myocardial fibrosis by late gadolinium enhancement imaging and biomarkers of collagen metabolism in chronic rheumatic mitral regurgitation.[Pubmed:29443354]
Journal of Cellular PhysiologyDNA methylation regulates α‐smooth muscle actin expression during cardiac fibroblast differentiation[Pubmed: 30362530]
International Journal of Chronic Obstructive Pulmonary DiseaseAltered serum levels of type I collagen turnover indicators accompanied by IL-6 and IL-8 release in stable COPD[Pubmed: 30655663]
Scientific ReportsLow fibrosis biomarker levels predict cardiac resynchronization therapy response[Pubmed: 30988339]
BoneAgonist-induced activation of the S1P receptor 2 constitutes a novel osteoanabolic therapy for the treatment of osteoporosis in mice[Pubmed: 31028959]
PLoS OneDeficiency of sphingosine-1-phosphate receptor 3 does not affect the skeletal phenotype of mice lacking sphingosine-1-phosphate lyase[Pubmed: 31314788]
BoneMice lacking plastin-3 display a specific defect of cortical bone acquisition[Pubmed: 31678489]
Journal of Diabetes ResearchType 2 Diabetes Mellitus and Chronic Heart Failure with Midrange and Preserved Ejection Fraction: A Focus on Serum Biomarkers of Fibrosis[Pubmed: 33224989]
JOURNAL OF BONE AND MINERAL RESEARCHPiezo1 Inactivation in Chondrocytes Impairs Trabecular Bone Formation[Pubmed: 33180356]
Microbiome changes in patients with chronic heart failure with preserved ejection fraction correlate with fibrosis markers: Description of a Russian cohort[]
Ассоциации толщины эпикардиального жира и циркулирующих маркеров фиброза миокарда у пациентов с инфарктом миокарда[]
Russian Journal of CardiologyEarly diagnosis of myocardial fibrosis in patients with epicardial obesity[]
J Diabetes ResAssociation between Markers of Fibrosis and Heart Failure Incidence in Patients with Type 2 Diabetes Mellitus[34778465]
Clinical, Cosmetic and Investigational DermatologyExtra Cellular Matrix Deposition and Assembly in Dermis Spheroids[34321901]
Scandinavian Cardiovascular JournalDual integrin αvβ3 and αvβ5 blockade attenuates cardiac dysfunction by reducing fibrosis in a rat model of doxorubicin-induced cardiomyopathy[34296634]
Eur J Appl PhysiolEffects of 8-week increment aerobic exercise program on bone metabolism and body composition in young non-athletes[Pubmed:35141785]
J. Clin. MedSimple Predictors for Cardiac Fibrosis in Patients with Type 2 Diabetes Mellitus: The Role of Circulating Biomarkers and Pulse Wave Velocity[Pubmed:35628969]