Ⅰ型前胶原羧基端原肽(PICP)多克隆抗体
Polyclonal Antibody to Procollagen I C-Terminal Propeptide (PICP)
P1CP; C-Propeptide Of Type I Procollagen; Procollagen I Carboxy Terminal Propeptide
- 编号PAA570Hu01
- 物种Homo sapiens (Human,人)相同的名称,不同的物种。
- 来源多抗制备
- 宿主兔
- 效价-
- Ig类型IgG
- 纯化方式抗原特异性亲和纯化
- 标记物无标记物
- 免疫原CPA570Hu21-Ⅰ型前胶原羧基端原肽(PICP)卵白蛋白偶联物
- 缓冲液成份磷酸盐缓冲液(pH7.4,含有0.02% NaN3和50%甘油)
- 性状液体
- 浓度0.5mg/mL
- 且适物种Mus musculus (Mouse,小鼠)
- 应用WB; IHC; ICC; IP.
如果抗体需用于流式细胞术,请参见流式抗体。 - 下载英文说明书 中文说明书
- 规格20µl100µl200µl1ml10ml
- 价格¥ 641 ¥ 1495¥ 2136¥ 5340¥ 21360
- 欲了解实际交易价格和更多情况,请与当地经销商联系!
特异性
该抗体是针对PICP的兔多克隆抗体。在免疫组织化学染色和免疫印迹实验中能识别PICP。
用法
Western blotting: 0.01-2µg/mL;
Immunohistochemistry: 5-20µg/mL;
Immunocytochemistry: 5-20µg/mL;
Optimal working dilutions must be determined by end user.
储存
经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。
稳定性
热稳定性以损失率显示。损失率是由加速降解试验决定,具体方法如下:在37°C孵育48小时,没有显著的降解或者沉淀产生。保质期内,在适当的条件下存储,损失率低于5%。
赠品
相关产品
编号 | 适用物种:Homo sapiens (Human,人) | 应用(仅供研究使用,不用于临床诊断!) |
RPA570Hu01 | Ⅰ型前胶原羧基端原肽(PICP)重组蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
EPA570Hu61 | Ⅰ型前胶原羧基端原肽(PICP)真核蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
APA570Hu61 | Ⅰ型前胶原羧基端原肽(PICP)活性蛋白 | Cell culture; Activity Assays. |
CPA570Hu22 | Ⅰ型前胶原羧基端原肽(PICP)卵白蛋白偶联物 | Immunogen; SDS-PAGE; WB. |
CPA570Hu21 | Ⅰ型前胶原羧基端原肽(PICP)卵白蛋白偶联物 | Immunogen; SDS-PAGE; WB. |
PAA570Hu01 | Ⅰ型前胶原羧基端原肽(PICP)多克隆抗体 | WB; IHC; ICC; IP. |
PAA570Hu08 | Ⅰ型前胶原羧基端原肽(PICP)多克隆抗体 | WB; IHC; ICC; IP. |
SEA570Hu | Ⅰ型前胶原羧基端原肽(PICP)检测试剂盒(酶联免疫吸附试验法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
SCA570Hu | Ⅰ型前胶原羧基端原肽(PICP)检测试剂盒(化学发光免疫分析法) | Chemiluminescent immunoassay for Antigen Detection. |
LMA570Hu | Ⅰ型前胶原羧基端原肽(PICP)等多因子检测试剂盒(流式荧光发光法) | FLIA Kit for Antigen Detection. |
参考文献
杂志 | 参考文献 |
Nutrition | Dyslipidemic high-fat diet affects adversely bone metabolism in mice associated with impaired antioxidant capacity[ScienceDirect: S0899900709004717] |
American Heart Journal | Serum markers of deranged myocardial collagen turnover: their relation to malignant ventricular arrhythmias in cardioverter-defibrillator recipients with heart failure.[PubMed: 23067911] |
Journal of Hypertension | Circulating biomarkers of collagen metabolism in arterial hypertension: relevance of target organ damage[Pubmed: 23615327] |
Pancreatology | Cdkn1a is a key mediator of rat pancreatic stellate cell senescence[Pubmed: 23719597] |
The American Journal of Cardiology | Relation of burden of myocardial fibrosis to malignant ventricular arrhythmias and outcomes in Fabry disease[Pubmed:25073565] |
PLoS One. | An NMR Metabolomic Study on the Effect of Alendronate in Ovariectomized Mice[Pubmed:25184758] |
Journal of Bone and Mineral Research | The Anti-Osteoanabolic Function of Sclerostin is Blunted in Mice Carrying a High Bone Mass Mutation of Lrp5[Pubmed:25640331] |
Bone | The active role of osteoporosis in the interaction between osteoblasts and bone metastases[PubMed: 26057367] |
J Nutr Biochem | Consumption of vitamin D2[PubMed: 25792284] |
Bibliothekssystem Universität Hamburg | Bilaterale Kommunikation zwischen Osteoblasten und Osteoklasten[volltexte:2016] |
Inflammation Research | Fibrosis of extracellular matrix is related to the duration of the disease but is unrelated to the dynamics of collagen metabolism in dilated cardiomyopathy[pubmed:27516211] |
Heart & Vessels | Left ventricular reverse remodeling is not related to biopsy-detected extracellular matrix fibrosis and serum markers of fibrosis in dilated cardiomyopathy, regardless of the definition used for LVRR[pubmed:28004175] |
Scandinavian Journal of Rheumatology | The association between insulin-like growth factor 1 (IGF-1), IGF-binding proteins (IGFBPs), and the carboxyterminal propeptide of type I procollagen (PICP) in pre- and postmenopausal women with rheumatoid arthritis.[pubmed:27775453] |
Allergy and Asthma Proceedings | Effect of montelukast on markers of airway remodeling in children withasthma.[pubmed:27657514] |
Scandinavian Journal of Rheumatology | The association between insulin-like growth factor 1 (IGF-1), IGF-binding proteins (IGFBPs), and the carboxyterminal propeptide of type I procollagen (PICP) in pre- and postmenopausal women with rheumatoid arthritis[loi:irhe20] |
Conditional Mouse Models Support the Role of SLC39A14 (ZIP14) in Hyperostosis Cranialis Interna and in Bone Homeostasis[ISBN: 978-94-6299-582-6] | |
MOLECULAR MEDICINE REPORTS | Endothelial‑to‑mesenchymal transition in human idiopathic dilated cardiomyopathy[pubmed:29115553] |
Pediatrics and Neonatology | Age-related changes in biochemical bone profile in thalassemic children[pubmed:28967496] |
Heart and Vessels | Left ventricular reverse remodeling is not related to biopsy‑detected extracellular matrix fibrosis and serum markers of fibrosis in dilated cardiomyopathy, regardless of the definition used for LVRR[10.1007/s00380-016-0930-y] |
Journal of Bone and Mineral Research | The Lrp4 R1170Q homozygous knock‐in mouse recapitulates the bone phenotype of sclerosteosis in humans[pubmed:28477420] |
Cytokine | 12-month patterns of serum markers of collagen synthesis, transforming growth factor and connective tissue growth factor are similar in new-onset and chronic dilated cardiomyopathy in patients both with and without cardiac fibrosis.[pubmed:28460256] |
Advanced Healthcare Materials | Prognostic value of fibrosis-related markers in dilated cardiomyopathy: A link between osteopontin and cardiovascular events.[pubmed:29120858] |
Journal of Bone and Mineral Metabolism | Mutations That Alter the Carboxy‐Terminal‐Propeptide Cleavage Site of the Chains of Type I Procollagen Are Associated With a Unique Osteogenesis Imperfecta …[Pubmed:29669177] |
Cardiovascular Journal of Africa | Assessment of myocardial fibrosis by late gadolinium enhancement imaging and biomarkers of collagen metabolism in chronic rheumatic mitral regurgitation.[Pubmed:29443354] |
Journal of Cellular Physiology | DNA methylation regulates α‐smooth muscle actin expression during cardiac fibroblast differentiation[Pubmed: 30362530] |
International Journal of Chronic Obstructive Pulmonary Disease | Altered serum levels of type I collagen turnover indicators accompanied by IL-6 and IL-8 release in stable COPD[Pubmed: 30655663] |
Scientific Reports | Low fibrosis biomarker levels predict cardiac resynchronization therapy response[Pubmed: 30988339] |
Bone | Agonist-induced activation of the S1P receptor 2 constitutes a novel osteoanabolic therapy for the treatment of osteoporosis in mice[Pubmed: 31028959] |
PLoS One | Deficiency of sphingosine-1-phosphate receptor 3 does not affect the skeletal phenotype of mice lacking sphingosine-1-phosphate lyase[Pubmed: 31314788] |
Bone | Mice lacking plastin-3 display a specific defect of cortical bone acquisition[Pubmed: 31678489] |
Journal of Diabetes Research | Type 2 Diabetes Mellitus and Chronic Heart Failure with Midrange and Preserved Ejection Fraction: A Focus on Serum Biomarkers of Fibrosis[Pubmed: 33224989] |
JOURNAL OF BONE AND MINERAL RESEARCH | Piezo1 Inactivation in Chondrocytes Impairs Trabecular Bone Formation[Pubmed: 33180356] |
Microbiome changes in patients with chronic heart failure with preserved ejection fraction correlate with fibrosis markers: Description of a Russian cohort[] | |
Ассоциации толщины эпикардиального жира и циркулирующих маркеров фиброза миокарда у пациентов с инфарктом миокарда[] | |
Russian Journal of Cardiology | Early diagnosis of myocardial fibrosis in patients with epicardial obesity[] |
J Diabetes Res | Association between Markers of Fibrosis and Heart Failure Incidence in Patients with Type 2 Diabetes Mellitus[34778465] |
Clinical, Cosmetic and Investigational Dermatology | Extra Cellular Matrix Deposition and Assembly in Dermis Spheroids[34321901] |
Scandinavian Cardiovascular Journal | Dual integrin αvβ3 and αvβ5 blockade attenuates cardiac dysfunction by reducing fibrosis in a rat model of doxorubicin-induced cardiomyopathy[34296634] |
Eur J Appl Physiol | Effects of 8-week increment aerobic exercise program on bone metabolism and body composition in young non-athletes[Pubmed:35141785] |
J. Clin. Med | Simple Predictors for Cardiac Fibrosis in Patients with Type 2 Diabetes Mellitus: The Role of Circulating Biomarkers and Pulse Wave Velocity[Pubmed:35628969] |