武汉云克隆科技股份有限公司

含Ⅲ型纤连蛋白域蛋白5(FNDC5)重组蛋白

Recombinant Fibronectin Type III Domain Containing Protein 5 (FNDC5)

FRCP2; Irisin; Fibronectin type III repeat-containing protein 2

  • 含Ⅲ型纤连蛋白域蛋白5(FNDC5)重组蛋白产品包装(模拟)
  • 含Ⅲ型纤连蛋白域蛋白5(FNDC5)重组蛋白产品包装(模拟)
  • RPN576Mu01.jpgFigure. SDS-PAGE
  • Certificate通过ISO 9001、ISO 13485质量体系认证

序列

用法

Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

储存

避免反复冻融。2-8°C不超过一个月，-80°C不超过12个月。

稳定性

热稳定性以损失率显示。损失率是由加速降解试验决定，具体方法如下：在37°C孵育48小时，没有显著的降解或者沉淀产生。保质期内，在适当的条件下存储，损失率低于5%。

相关产品

编号适用物种：Mus musculus (Mouse，小鼠)应用(仅供研究使用，不用于临床诊断！)
APN576Mu61含Ⅲ型纤连蛋白域蛋白5(FNDC5)活性蛋白Cell culture; Activity Assays.
APN576Mu01含Ⅲ型纤连蛋白域蛋白5(FNDC5)活性蛋白Cell culture; Activity Assays.
RPN576Mu01含Ⅲ型纤连蛋白域蛋白5(FNDC5)重组蛋白Positive Control; Immunogen; SDS-PAGE; WB.
RPN576Mu02含Ⅲ型纤连蛋白域蛋白5(FNDC5)重组蛋白Positive Control; Immunogen; SDS-PAGE; WB.
PAN576Mu02含Ⅲ型纤连蛋白域蛋白5(FNDC5)多克隆抗体WB; IHC; ICC; IP.
PAN576Mu01含Ⅲ型纤连蛋白域蛋白5(FNDC5)多克隆抗体WB; IHC; ICC; IP.
SEN576Mu含Ⅲ型纤连蛋白域蛋白5(FNDC5)检测试剂盒(酶联免疫吸附试验法)Enzyme-linked immunosorbent assay for Antigen Detection.
LMN576Mu含Ⅲ型纤连蛋白域蛋白5(FNDC5)等多因子检测试剂盒(流式荧光发光法)FLIA Kit for Antigen Detection.

参考文献

杂志参考文献
Diabetes Research and Clinical PracticeSerum irisin levels in new-onset type 2 diabetes[PubMed: 23369227]
Journal of diabetes and its complicationsLower circulating irisin is associated with type 2 diabetes mellitus[Pubmed: 23619195]
Horm Metab Res.Inconsistency in circulating irisin levels: what is really happening[Pubmed:24459033]
Int J Obes (Lond).Leptin administration activates irisin-induced myogenesis via nitric oxide-dependent mechanisms, but reduces its effect on subcutaneous fat browning in mice[Pubmed:25199621]
Molecular and Cellular EndocrinologyFenofibrate (PPARalpha agonist) induces beige cell formation in subcutaneous white adipose tissue from diet-induced male obese mice[Pubmed:25576856]
journal of diabetesLower irisin level in patients with type 2 diabetes mellitus: A case-control study and meta-analysis[PubMed: 25494632]
The Journal of Maternal-Fetal & Neonatal MedicineMaternal circulating levels of irisin in intrahepatic cholestasis of pregnancy[PubMed: 26689349]
Hormone and Metabolic ResearchLower Circulating Irisin Level in Patients with Diabetes Mellitus: A Systematic Review and Meta-Analysis[Pubmed:27300472]
Nature Reviews EndocrinologyPhysiology and role of irisin in glucose homeostasis.[pubmed:28211512]
Journal of Molecular and Cellular CardiologyIrisin improves perivascular adipose tissue dysfunction via regulation of the heme oxygenase-1/adiponectin axis in diet-induced obese mice[pubmed:27638193]
Biochemical and Biophysical Research Communications Irisin stimulates cell proliferation and invasion by targeting the PI3K/AKT pathway in human hepatocellular carcinoma [pubmed:28867187]
PLoS OneDifferential actions of PPAR-α and PPAR-β/δ on beige adipocyte formation: A study in the subcutaneous white adipose tissue of obese male mice[Pubmed:29351550]
International Brazilian Journal of UrologyThe Diagnostic Value of FNDC5/Irisin in Renal Cell Cancer.[Pubmed:29522296]
Redox BiologyIrisin alleviates liver ischemia-reperfusion injury by inhibiting excessive mitochondrial fission, promoting mitochondrial biogenesis and decreasing oxidative …[Doi: 10.1016/j.redox.2018.10.019]
Antioxidants & redox signalingLow serum irisin concentration is associated with poor outcomes in patients with acute pancreatitis and irisin administration protects against experimental acute …[Pubmed: 31250660]
Journal of Maternal-Fetal & Neonatal MedicineMaternal serum, placental, and umbilical venous blood irisin levels in intrahepatic cholestasis of pregnancy[Pubmed: 31590596]
Biomed PharmacotherIdentification of irisin as a therapeutic agent that inhibits oxidative stress and fibrosis in a murine model of chronic pancreatitis[Pubmed: 32199226]
Irisin Improves Autophagy of Aged Hepatocytes via Increasing Telomerase Activity in Liver Injury[Pubmed: 31976032]
Serum Irisin Predicts Posthepatectomy Complications in Patients with Hepatocellular Carcinoma[Pubmed: 31976024]
DOMESTIC ANIMAL ENDOCRINOLOGYThe myokine Irisin: localization and effects in swine late medium and large antral ovarian follicle[Pubmed: 33120167]
Journal of Biomaterials and Tissue EngineeringThe Combination of Aerobic and Resistance Exercise Induces Weight Loss via the PGC-1α/Irisin/UCP-1 Pathway[]
Evaluation of a recombinant bacillus calmette-guérin vaccine expressing P39-L7/L12 of Brucella melitensis: An immunization strategy against brucellosis in BALB/c …[]
Eur Rev Med Pharmacol SciSalivary Irisin: potential inflammatory biomarker in recurrent apthous stomatitis patients[33755963]
MetabolitesPattern of Adiponectin, Osteocalcin, Irisin, FGF-21, and MCP-1 According to the Body Size Phenotype: Could They Be Markers of Metabolic Health in Mexican-Mestizo …[34822430]
Eat Weight DisordTime-restricted feeding prevents metabolic diseases through the regulation of galanin/GALR1 expression in the hypothalamus of mice[34370270]
Ir J Med SciEight-week exercise program improved the quality of life of Alzheimer's patients through functional, cognitive, and biochemical parameters[Pubmed:35604540]
Biomed PharmacotherIrisin attenuates sepsis-induced cardiac dysfunction by attenuating inflammation-induced pyroptosis through a mitochondrial ubiquitin ligase-dependent …[Pubmed:35653888]
Journal of King Saud University - ScienceInteraction of nitric oxide synthase and mitochondrial ATP-sensitive potassium channels in protective impacts of combination therapy with irisin …[]