生长分化因子15(GDF15)重组蛋白
Recombinant Growth Differentiation Factor 15 (GDF15)
PDF; MIC1; NAG-1; PLAB; PTGFB; Macrophage inhibitory cytokine 1; NSAID-activated gene 1 protein; Placental bone morphogenetic protein; Prostate differentiation factor
- 编号RPC034Si01
- 物种Rhesus monkey (Simian，恒河猴)相同的名称，不同的物种。
- 来源原核表达
- 宿主E.coli
- 内毒素水平<1.0EU/µg(LAL法测定)
- 亚细胞定位分泌
- 预测分子量16.6kDa
- 实际分子量19kDa(差异分析请参阅说明书)
- 片段与标签Arg193~Val308 with N-terminal His Tag
- 缓冲液成份20mM Tris, 150mM NaCl缓冲液（pH8.0, 含有1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose和Proclin300）
- 性状冻干粉
- 纯度> 95%
- 等电点8.1
- 应用Positive Control; Immunogen; SDS-PAGE; WB.
如果需要有生物活性的蛋白，请参见活性蛋白。 - 下载英文说明书 中文说明书
- 规格10µg50µg200µg1mg5mg
- 价格¥ 1416¥ 3540¥ 7080¥ 21240¥ 53100
- 欲了解实际交易价格和更多情况，请与当地经销商联系!
序列
用法
Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
储存
避免反复冻融。2-8°C不超过一个月，-80°C不超过12个月。
稳定性
热稳定性以损失率显示。损失率是由加速降解试验决定，具体方法如下：在37°C孵育48小时，没有显著的降解或者沉淀产生。保质期内，在适当的条件下存储，损失率低于5%。
增值服务
相关产品
| 编号 | 适用物种：Rhesus monkey (Simian，恒河猴) | 应用(仅供研究使用，不用于临床诊断！) |
| RPC034Si01 | 生长分化因子15(GDF15)重组蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| SEC034Si | 生长分化因子15(GDF15)检测试剂盒(酶联免疫吸附试验法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
参考文献
| 杂志 | 参考文献 |
| Clinical cardiology | Growth Differentiation Factor 15 and Coronary Collateral Formation[PubMed: 20014173] |
| Personalized Medicine | Elevated levels of GDF-15 is associated with increased angiotensin II in hypertensive patients with Type 2 diabetes[pme-2016-0030] |
| LIFE SCIENCES | Rapamycin improves renal injury induced by Iodixanol in diabetic rats by deactivating the mTOR/p70S6K signaling pathway[Pubmed: 32798557] |
| Microbiome changes in patients with chronic heart failure with preserved ejection fraction correlate with fibrosis markers: Description of a Russian cohort[] | |
| SEMINARS IN DIALYSIS | Serum NT©\proBNP levels are associated with cognitive functions in hemodialysis patients[33423325] |
| Taiwanese Journal of Obstetrics & Gynecology | Is GDF-15 level associated with gestational diabetes mellitus and adverse perinatal outcomes?[33678319] |
| J Inflamm Res | Changes in Plasma Growth Differentiation Factor-15 After Laparoscopic Sleeve Gastrectomy in Morbidly Obese Patients: A Prospective Study[33880052] |
| Russian Journal of Cardiology | Predictive value of growth differentiation factor-15 in patients with myocardial infarction[] |
| Nutrients | High Fat, High Sugar Diet and DJOS Bariatric Surgery Influence Plasma Levels of Fetuin-B, Growth Differentiation Factor-15, and Pentraxin 3 in Diet-Induced Obese …[34684637] |
| Nat Metab | Small extracellular vesicle-mediated targeting of hypothalamic AMPKα1 corrects obesity through BAT activation[34675439] |
| Acta Cardiol Sin | Growth Differentiation Factor 15 is Related with Left Ventricular Recovery in Patients with ST-Elevation Myocardial Infarction after Successful Reperfusion by …[34584380] |
| Surgical Endoscopy | The effect of bariatric surgery on the expression of Growth Differentiation Factor-15/Macrophage-Inhibitory Cytokine-1 (GDF-15/MIC-1) in rat[Pubmed:35029766] |
| Journal of Clinical Laboratory Analysis | Plasma growth differentiation factor‐15 in patients with “lone” atrial fibrillation[Pubmed:35334497] |