高温需求因子A1(HTRA1)重组蛋白
Recombinant High Temperature Requirement Factor A1 (HTRA1)
HtrA; L56; ORF480; PRSS11; HtrA Serine Peptidase 1; Protease,Serine,11; IGFBP5-Protease; High-temperature requirement A serine peptidase 1
- 编号RPL604Co01
- 物种Escherichia coli(大肠杆菌)相同的名称，不同的物种。
- 来源原核表达
- 宿主E.coli
- 内毒素水平<1.0EU/µg(LAL法测定)
- 亚细胞定位分泌
- 预测分子量15.4kDa
- 实际分子量16kDa(差异分析请参阅说明书)
- 片段与标签Ala10~Gly146 with N-terminal His Tag
- 缓冲液成份100mM NaHCO3, 500mM NaCl缓冲液（pH8.3,含有1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose和Proclin300）
- 性状冻干粉
- 纯度> 97%
- 等电点5.7
- 应用Positive Control; Immunogen; SDS-PAGE; WB.
如果需要有生物活性的蛋白，请参见活性蛋白。 - 下载英文说明书 中文说明书
- 规格10µg50µg200µg1mg5mg
- 价格¥ 1056¥ 2640¥ 5280¥ 15840¥ 39600
- 欲了解实际交易价格和更多情况，请与当地经销商联系!
产品包装(模拟)
产品包装(模拟)
SDS-PAGE图
通过ISO 9001、ISO 13485质量体系认证
序列
用法
Reconstitute in ddH2O to a concentration of 0.1-1.0 mg/mL. Do not vortex.
储存
避免反复冻融。2-8°C不超过一个月，-80°C不超过12个月。
稳定性
热稳定性以损失率显示。损失率是由加速降解试验决定，具体方法如下：在37°C孵育48小时，没有显著的降解或者沉淀产生。保质期内，在适当的条件下存储，损失率低于5%。
增值服务
相关产品
| 编号 | 适用物种：Escherichia coli(大肠杆菌) | 应用(仅供研究使用，不用于临床诊断！) |
| RPL604Co02 | 高温需求因子A1(HTRA1)重组蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPL604Co01 | 高温需求因子A1(HTRA1)重组蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| PAL604Co01 | 高温需求因子A1(HTRA1)多克隆抗体 | WB; IHC; ICC; IP. |
| PAL604Co02 | 高温需求因子A1(HTRA1)多克隆抗体 | WB |
参考文献
| 杂志 | 参考文献 |
| Placenta | Alterations of maternal plasma HTRA1 level in preeclampsia complicated by IUGR[PubMed: 23083999] |
| Placenta | Upregulation of HtrA4 in the placentas of patients with severe pre-eclampsia[PubMed: 22964307] |
| Exp Gerontol | Association of frailty with the serine protease HtrA1 in older adults[Pubmed:27058767] |
| International Journal of Clinical and Experimental Pathology | HtrA1 up-regulates expression of MMPs via Erk1/2/Rock-dependent pathways[files:ijcep0069706.pdf] |
| Pregnancy Hypertension | Association between first trimester plasma htra1 level and subsequent preeclampsia: a possible early marker?[] |
| American journal of translational research | HtrA1 upregulates the expression of ADAMTS-5 in HNPCs via the ERK/NF-κB/JNK signaling pathway[Pubmed: 31497227] |
| J Matern Fetal Neonatal Med | First trimester HtrA1 maternal plasma level and spontaneous preterm birth[Pubmed: 32102578] |
| BMC Geriatr | Cross-sectional associations among P3NP, HtrA, Hsp70, Apelin and sarcopenia in Taiwanese population[33743591] |