武汉云克隆科技股份有限公司

产品货号：RPA033Eq01  

产品名称：干扰素α(IFNa)重组蛋白 

文献名称：A viral infection-biomimetic strategy for Antibody-Guided Targeted Protein Degradation  

杂志名称：Acta Biomaterialia     

影响因子：9.6

PMID/DOI：40846095 

发表日期：8/20/2025  

发表单位：北京大学医学部基础医学院系统生物医学研究所肿瘤系统生物学北京市重点实验室

样本类型：人单核细胞白血病细胞THP-1，人宫颈癌细胞HeLa

应用类型：细胞培养

(G) IFN-α treatment elevated TRIM21 mRNA levels. Real-time PCR was used to analyze TRIM21 mRNA in THP-1 cells treated with varying concentrations of IFN-α for the indicated time periods. Results were normalized to HPRT1 expression. (n=3) (H) IFN-α treatment increased TRIM21 expression. TRIM21 levels were analyzed by WB in HeLa cells treated with varying concentrations of IFN-α for the indicated times.

产品货号：RPA164Mi01 

产品名称：泛素(Ub)重组蛋白 

文献名称：Degradation of IRF6 by TRIM59 in tumor cells triggers PGM1-mediated glycolysis to regulate cell proliferation in neuroblastoma  

杂志名称：Cell Death & Disease     

影响因子：9.6

PMID/DOI：40796729 

发表日期：8/12/2025  

发表单位：韩国全南大学医院生物医学研究所 

样本类型：纯化GST-TRIM59蛋白

应用类型：酶催化

O Purified GST-TRIM59 was incubated with the indicated reaction components. The reaction mixture was subjected to Western blot using antibodies against ubiquitin, Myc, and GST. 

产品货号：RPB019Hu01 

产品名称：血管生成素样蛋白4(ANGPTL4)重组蛋白 

文献名称：ANGPTL4 Prevents Atherosclerosis by Preserving KLF2 to Suppress EndMT and Mitigates Endothelial Dysfunction  

杂志名称：Arteriosclerosis Thrombosis and Vascular Biology     

影响因子：7.4

PMID/DOI：40808654 

发表日期：8/14/2025  

发表单位：韩国全南大学医院生物医学研究所 

样本类型：人脐静脉内皮细胞（HUVECs），人主动脉内皮细胞（HAECs）

应用类型：细胞培养

B, Quantitative polymerase chain reaction (PCR) analysis of inflammatory gene expression in human umbilical vein endothelial cells (HUVECs) pretreated with recombinant human ANGPTL4 (0.3, 1, or 3 µg/mL) for 15 hours, followed by stimulation with TNF-α (tumor necrosis factor alpha; 10 ng/mL) for 6 hours. Expression of CD31, ICAM1, VCAM1, SELE, CCL2, and IL-1β was normalized to GAPDH. n=4 biological replicates per group. C, Immunofluorescence staining of HUVECs showing ICAM1 (red), VCAM1 (red), and CD31 (green) under TNF-α stimulation with or without ANGPTL4 (1 or 3 µg/mL). Quantification of ICAM1/CD31 and VCAM1/CD31 fluorescence intensity ratios is shown at right. n=6 fields per condition. Scale bar, 20 µm.

D, Human aortic endothelial cells (HAECs) were stimulated with TNF-α with or without ANGPTL4 and stained with VE-cadherin (VE-coronary artery disease [CAD]; green) and ICAM1 (red). Quantification of ICAM1/VE-CAD fluorescence intensity ratios is shown. n=6 fields per condition. Scale bar, 50 µm.