速看!12月明星蛋白清单,高效科研之选

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01  ADM     

产品货号:APA220Mu01 

产品名称:肾上腺髓质素(ADM)活性蛋白

文献名称:METTL14 integrates tumor-derived SAM to drive parabrachial epigenetic rewiring in pancreatic cancer 

杂志名称:Neuron      

影响因子:15.0

PMID/DOI:10.1016/j.neuron.2025.10.002

发表日期: 11/1/2025  

发表单位:中国广东省广州市肿瘤防治中心中山大学肿瘤防治中心麻醉科

样本类型:小鼠外侧臂旁核谷氨酸能神经元(LPBN)

应用类型:细胞培养

METTL14-mediated m6A modification drives comorbidity via ADM in LPBN glutamatergic neurons(E) LPBN Adm mRNA expression (n = 7). (F) ADM protein levels in the LPBN (n = 10). (H) MeRIP-qPCR measuring m6A levels on Adm mRNA in LPBN (n = 4).




02  CX3CL1    

产品货号:APA040Hu01  

产品名称:趋化因子C-X3-C-基元配体1(CX3CL1)活性蛋白 

文献名称:Heat Stress Modulates WDR5‐Mediated H3K4me3 Modification to Induce Melanogenesis via Activating CX3CL1/CX3CR1 Axis  

杂志名称:Advanced Science       

影响因子:14.1

PMID/DOI:41267387 

发表日期: 11/20/2025  

发表单位:中南大学湘雅三医院皮肤科,中南大学湘雅二医院临床研究中心

样本类型:人黑色素原代细胞(MC)、人黑色素瘤细胞(MNT1)

应用类型:细胞培养

CX3CL1 can promote melanogenesis. a,b) MNT1 or MC cells were treated with α-MSH or CX3CL1: after 24 h, the melanin content in the cells was detected by Fontana-Masson staining (scale =20 µm), and quantitative analysis was performed using ImageJ (a);



03  ITGb3     

产品货号:RPD353Mu01  

产品名称:Slit同源物3(Slit3)重组蛋白 

文献名称:Osteoclast‐Derived SLIT3 Mediates Osteoarthritis Pain and Degenerative Changes  

杂志名称:Advanced Science       

影响因子:14.1

PMID/DOI:41255240 

发表日期: 11/19/2025  

发表单位:中国空军军医大学唐都医院口腔科/口腔颌面重建与再生全国重点实验室

样本类型:小鼠三叉神经节细胞(TG)

应用类型:细胞培养

To further verify the role of osteoclasts, we added 500 µg mL−1 SLIT3 protein to the co-culture medium in vitro, which significantly promoted the growth of sensory neuron axons (Figure 6f–h). 

Figure6 f) Quantitative analysis in panel (h). n = 6. g) Schematic diagram for extracting trigeminal ganglion (TG) cells. h) Representative microscopy images of TG cells after different treatments.