双调蛋白(AREG)重组蛋白
Recombinant Amphiregulin (AREG)
AR; CRDGF; SDGF; Colorectum Cell-Derived Growth Factor; Schwannoma-Derived Growth Factor
- 编号RPA006Hu01
- 物种Homo sapiens (Human，人)相同的名称，不同的物种。
- 来源原核表达
- 宿主E.coli
- 内毒素水平<1.0EU/µg(LAL法测定)
- 亚细胞定位Membrane; Single-pass membrane prote
- 预测分子量40.7kDa
- 实际分子量44kDa(差异分析请参阅说明书)
- 片段与标签Ser20~Asp100 with N-terminal His and GST Tag
- 缓冲液成份磷酸盐缓冲液（pH7.4，含有 0.01% SKL, 1mM DTT, 5% Trehalose和Proclin300.）
- 性状冻干粉
- 纯度> 95%
- 等电点5.1
- 应用Positive Control; Immunogen; SDS-PAGE; WB.
如果需要有生物活性的蛋白，请参见活性蛋白。 - 下载英文说明书 中文说明书
- 规格10µg50µg200µg1mg5mg
- 价格¥ 960¥ 2400¥ 4800¥ 14400¥ 36000
- 欲了解实际交易价格和更多情况，请与当地经销商联系!
产品包装(模拟)
产品包装(模拟)
Figure. Gene Sequencing (Extract)
SDS-PAGE图
通过ISO 9001、ISO 13485质量体系认证
序列
用法
PBS或其它。
储存
避免反复冻融。2-8°C不超过一个月，-80°C不超过12个月。
稳定性
热稳定性以损失率显示。损失率是由加速降解试验决定，具体方法如下：在37°C孵育48小时，没有显著的降解或者沉淀产生。保质期内，在适当的条件下存储，损失率低于5%。
增值服务
相关产品
| 编号 | 适用物种：Homo sapiens (Human，人) | 应用(仅供研究使用，不用于临床诊断！) |
| APA006Hu01 | 双调蛋白(AREG)活性蛋白 | Cell culture; Activity Assays. |
| RPA006Hu01 | 双调蛋白(AREG)重组蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| PAA006Hu01 | 双调蛋白(AREG)多克隆抗体 | WB; IHC |
| MAA006Hu23 | 双调蛋白(AREG)单克隆抗体 | WB; IHC; ICC; IP. |
| MAA006Hu25 | 双调蛋白(AREG)单克隆抗体 | WB; IHC; ICC; IP. |
| MAA006Hu22 | 双调蛋白(AREG)单克隆抗体 | WB; IHC |
| MAA006Hu24 | 双调蛋白(AREG)单克隆抗体 | WB; IHC; ICC/IF |
| MAA006Hu26 | 双调蛋白(AREG)单克隆抗体 | WB; IHC |
| MAA006Hu21 | 双调蛋白(AREG)单克隆抗体 | WB; IHC; ICC; IP. |
| MAA006Hu27 | 双调蛋白(AREG)单克隆抗体 | WB; IHC; ICC; IP. |
| MAA006Hu29 | 双调蛋白(AREG)单克隆抗体 | WB; IHC; ICC; IP. |
| LAA006Hu76 | 双调蛋白(AREG)单克隆抗体(生物素标记) | WB; IHC; ICC. |
| SEA006Hu | 双调蛋白(AREG)检测试剂盒(酶联免疫吸附试验法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| SCA006Hu | 双调蛋白(AREG)检测试剂盒(化学发光免疫分析法) | Chemiluminescent immunoassay for Antigen Detection. |
| LMA006Hu | 双调蛋白(AREG)等多因子检测试剂盒(流式荧光发光法) | FLIA Kit for Antigen Detection. |
| PSA006Hu01 | 双调蛋白(AREG)抗体对 | ELISA; CLIA; ELISPOT; Luminex; Immunochromatography and other Immunoassays. |
| KSA006Hu01 | 双调蛋白(AREG)检测试剂盒DIY材料(酶联免疫吸附试验法) | Main materials for "Do It (ELISA Kit) Yourself". |
参考文献
| 杂志 | 参考文献 |
| Onkologie | Amphiregulin and Epiregulin Expression in Colorectal Carcinoma and the Correlation with Clinicopathological Characteristics[Karger: 315380] |
| Br J Cancer. | Serum levels of hepatocyte growth factor and epiregulin are associated with the prognosis on anti-EGFR antibody treatment in KRAS wild-type metastatic colorectal cancer.[Pubmed:24800946] |
| Cancer Sci | Association between serum ligands and the skin toxicity of anti-epidermal growth factor receptor antibody in metastatic colorectal cancer[PubMed: 25707609] |
| J Cancer Res Clin Oncol | Amphiregulin confers trastuzumab resistance via AKT and ERK activation in HER2-positive breast cancer[PubMed: 26195282] |
| Oncotarget. | Serum level of hepatocyte growth factor is a novel marker of predicting theoutcome and resistance to the treatment with trastuzumab in HER2-positive patients with metastatic gastric cancer[Pubmed:26716644] |
| Acta Pharmacologica Sinica | Anti-asthmatic activity of alkaloid compounds from Pericarpium Citri Reticulatae (Citrus reticulata 'Chachi')[Pubmed: 19363516] |
| International Journal of Biological Sciences | CD9 regulates keratinocyte migration by negatively modulating the sheddase activity of ADAM17[] |
| Neoplasia | Patient-derived xenograft (PDX) models of colorectal carcinoma (CRC) as a platform for chemosensitivity and biomarker analysis in personalized medicine[Pubmed: 33212364] |
| JOURNAL OF CELLULAR AND MOLECULAR MEDICINE | Polarization of ADAM17‐driven EGFR signalling in electric field‐guided collective migration of epidermal sheets[Pubmed: 33164313] |