血管紧张素转化酶2(ACE2)单克隆抗体
Monoclonal Antibody to Angiotensin I Converting Enzyme 2 (ACE2)
ACEH; ACEII; ACE-II; Peptidyl-Dipeptidase A; ACE-related carboxypeptidase; Angiotensin-converting enzyme homolog; Metalloprotease MPROT15
- 编号MAB886Hu22
- 物种Homo sapiens (Human，人)相同的名称，不同的物种。
- 来源单抗制备
- 宿主小鼠
- 效价(克隆号)C15
- Ig亚型 IgG1 Kappa
- 纯化方式蛋白A + 蛋白G亲和纯化
- 标记物无标记物
- 免疫原RPB886Hu01-血管紧张素转化酶2(ACE2)重组蛋白
- 缓冲液成份0.01M 磷酸盐缓冲液（pH7.4，containing 0.05% Proclin-300，50% glycerol）
- 性状液体
- 浓度1mg/mL
- 且适物种Mus musculus (Mouse，小鼠), Sus scrofa; Porcine (Pig，猪)
- 应用WB; IHC; ICC; IP.
如果抗体需用于流式细胞术，请参见流式抗体。 - 下载英文说明书 中文说明书
- 规格20µl100µl200µl1ml10ml
- 价格¥ 522¥ 1218¥ 1740¥ 4350¥ 17400
- 欲了解实际交易价格和更多情况，请与当地经销商联系!
特异性
该抗体是针对ACE2的小鼠单克隆抗体。在免疫组织化学染色和免疫印迹实验中能识别ACE2。
用法
Western blotting: 0.01-2µg/mL;
Immunohistochemistry: 5-20µg/mL;
Immunocytochemistry: 5-20µg/mL;
Optimal working dilutions must be determined by end user.
储存
经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。
稳定性
热稳定性以损失率显示。损失率是由加速降解试验决定，具体方法如下：在37°C孵育48小时，没有显著的降解或者沉淀产生。保质期内，在适当的条件下存储，损失率低于5%。
赠品
增值服务
相关产品
| 编号 | 适用物种：Homo sapiens (Human，人) | 应用(仅供研究使用，不用于临床诊断！) |
| EPB886Hu61 | 血管紧张素转化酶2(ACE2)真核蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| APB886Hu01 | 血管紧张素转化酶2(ACE2)活性蛋白 | Cell culture; Activity Assays. |
| APB886Hu61 | 血管紧张素转化酶2(ACE2)活性蛋白 | Cell culture; Activity Assays. |
| RPB886Hu01 | 血管紧张素转化酶2(ACE2)重组蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPB886Hu02 | 血管紧张素转化酶2(ACE2)重组蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| PAB886Hu02 | 血管紧张素转化酶2(ACE2)多克隆抗体 | WB; IHC; ICC; IP. |
| PAB886Hu01 | 血管紧张素转化酶2(ACE2)多克隆抗体 | WB; IHC; ICC; IP. |
| MAB886Hu23 | 血管紧张素转化酶2(ACE2)单克隆抗体 | WB; IHC; ICC; IP. |
| MAB886Hu24 | 血管紧张素转化酶2(ACE2)单克隆抗体 | WB; IHC; ICC; IP. |
| MAB886Hu25 | 血管紧张素转化酶2(ACE2)单克隆抗体 | WB; IHC; ICC; IP. |
| MAB886Hu21 | 血管紧张素转化酶2(ACE2)单克隆抗体 | WB; IHC |
| MAB886Hu22 | 血管紧张素转化酶2(ACE2)单克隆抗体 | WB; IHC; ICC; IP. |
| FAB886Hu08 | 抗血管紧张素转化酶2(ACE2)单克隆抗体 | Flow cytometry. |
| FAB886Hu04 | 抗血管紧张素转化酶2(ACE2)单克隆抗体 | Flow cytometry. |
| FAB886Hu02 | 抗血管紧张素转化酶2(ACE2)单克隆抗体 | Flow cytometry. |
| FAB886Hu06 | 抗血管紧张素转化酶2(ACE2)单克隆抗体 | Flow cytometry. |
| SEB886Hu | 血管紧张素转化酶2(ACE2)检测试剂盒(酶联免疫吸附试验法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| AEB886Hu | 抗血管紧张素转化酶2抗体(Anti-ACE2)检测试剂盒(酶联免疫吸附试验法) | Enzyme-linked immunosorbent assay for Antibody Detection. |
| LMB886Hu | 血管紧张素转化酶2(ACE2)等多因子检测试剂盒(流式荧光发光法) | FLIA Kit for Antigen Detection. |
参考文献
| 杂志 | 参考文献 |
| Nature Medicine | Angiotensin-Converting Enzyme 2 Overexpression Remarkably Ameliorated Glomerular Injury in a Rat Model of Diabetic Nephropathy: A Comparison with ACE Inhibition[MolMed: 10_11_liu] |
| Journal of Cancer Therapy | Plasma Levels of Angiotensin-Converting Enzymes 1 and 2 and AGTR2 (T1247G and A5235G) Gene Polymorphisms Are Associated to Breast Cancer Progression.[Scirp: Source] |
| Reprod Toxicol.? | ACE2 activation by xanthenone prevents leptin-induced increases in blood pressure and proteinuria during pregnancy in Sprague-Dawley rats[Pubmed:25205467] |
| Intensive Care Medicine Experimental | Angiotensin converting enzymes in patients with acute respiratory distress syndrome[Content: 3] |
| Journal of Chromatography A | Application of a new procedure for liquid chromatography/mass spectrometry profiling of plasma amino acid-related metabolites and untargeted shotgun proteomics to identify mechanisms and biomarkers of calcific aortic stenosis[S0021967317311858] |
| Journal of Clinical Pharmacy and Therapeutics | Relationship between genetic variants of ACE2 gene and circulating levels of ACE2 and its metabolites.[pubmed:28895159] |
| Innate Immunity | Lipoxin A attenuates LPS-induced acute lung injury via activation of the ACE2-Ang-(1-7)-Mas axis[Pubmed:29969931] |
| Journal of Surgical Research | Impact of angiotensin-converting enzyme 2 levels on postoperative pneumonia after esophagectomy[Pubmed:29506841] |
| canadian journal of physiology and pharmacology | Could cardioprotective effect of ACE2 activator “diminazene aceturate” is more potent than ACE inhibitor “Enalapril” on acute myocardial infarction in rats?[Pubmed: 30840489] |
| Intensive Care Medicine | Angiotensin-converting enzymes in acute respiratory distress syndrome[] |
| BioMed Research International | AVE 0991 Attenuates Pyroptosis and Liver Damage after Heatstroke by Inhibiting the ROS-NLRP3 Inflammatory Signalling Pathway[] |
| Heart and vessels | Relationship between circulating levels of angiotensin-converting enzyme 2-angiotensin-(1–7)-MAS axis and coronary heart disease[Pubmed: 31359146] |
| Medicine | Alteration and association between serum ACE2/angiotensin (1-7)/Mas axis and oxidative stress in chronic kidney disease: A pilot study[Pubmed: 32756181] |
| American Journal of Respiratory and Critical Care Medicine | Equilibrium Angiotensin Metabolite Profiling in Patients with Acute Respiratory Distress Syndrome Indicates Angiotensin Converting Enzyme Inhibition[Pubmed: 32628511] |
| Clinical Research in Cardiology | Determinants of soluble angiotensin-converting enzyme 2 concentrations in adult patients with complex congenital heart disease[33280062] |
| Clinical & Translational Immunology | Pattern of circulating SARS©\CoV©\2©\specific antibody©\secreting and memory B©\cell generation in patients with acute COVID©\19[33552508] |
| researchsquare | Novel transgenic mice with Cre-dependent co-expression of GFP and human ACE2: a safe tool for study of COVID-19 pathogenesis[33855640] |
| Viruses | Different Neutralization Sensitivity of SARS-CoV-2 Cell-to-Cell and Cell-Free Modes of Infection to Convalescent Sera[] |
| Sci Rep | Immunoreactivity of the SARS-CoV-2 entry proteins ACE-2 and TMPRSS-2 in murine models of hormonal manipulation, ageing, and cardiac injury[34907257] |
| European Journal of Clinical Investigation | Angiotensin‐converting enzyme 2 and Transmembrane protease serine 2 in female and male patients with end‐stage kidney disease[Pubmed:35366343] |
| Metabolites | Ramipril Reduces Acylcarnitines and Distinctly Increases Angiotensin-Converting Enzyme 2 Expression in Lungs of Rats[Pubmed:35448480] |