亲环素A(CYPA)单克隆抗体

Monoclonal Antibody to Cyclophilin A (CYPA)

PPIA; CyP-A; CYPH; Peptidylprolyl Isomerase A; Peptidyl-Prolyl Isomerase A; Peptidyl-prolyl cis-trans isomerase A; Cyclosporin A-binding protein

  • 亲环素A(CYPA)单克隆抗体产品包装(模拟)
  • 亲环素A(CYPA)单克隆抗体产品包装(模拟)
  • 亲环素A(CYPA)单克隆抗体DAB staining on IHC-P; Samples: Human Colorectal cancer Tissue; Primary Ab: 20µg/ml Mouse Anti-Human CYPA Antibody Second Ab: 2µg/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody (Catalog: SAA544Mu19)
  • 亲环素A(CYPA)单克隆抗体DAB staining on IHC-P;
    Samples: Human Kidney Tissue;
    Primary Ab: 20µg/ml Mouse Anti-Human CYPA Antibody
    Second Ab: 2µg/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody
    (Catalog: SAA544Mu19)
  • 亲环素A(CYPA)单克隆抗体AF488 staining on IF;
    Sample: Human LO2 cell;
    Primary Ab: 30ug/ml Mouse Anti-Human CYPA Antibody
    Second Ab: 1µg/ml AF488-Linked Caprine Anti-Mouse IgG Polyclonal Antibody
    (Catalog: SAA544Mu11)
  • MAA979Hu22.jpgWestern Blot; Sample: Lane1: Porcine Liver lysate; Lane2: Rat Liver lysate; Lane3: HepG2 cell lysate Primary Ab: 0.2µg/ml Mouse Anti-Human CYPA Antibody Second Ab: 0.2µg/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody (Catalog: SAA544Mu19)
  • 亲环素A(CYPA)单克隆抗体Figure. Western Blot; Sample: Lane1: Human Liver Tissue; Lane2: Porcine Liver Tissue.
  • 亲环素A(CYPA)单克隆抗体Western Blot; Sample: Human HepG2 cell lysate;
    Primary Ab: 2µg/ml Mouse Anti-Human CYPA Antibody
    Second Ab: 0.2µg/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody
    (Catalog: SAA544Mu19)
  • Certificate通过ISO 9001、ISO 13485质量体系认证

特异性

该抗体是针对CYPA的小鼠单克隆抗体。在免疫组织化学染色和免疫印迹实验中能识别CYPA。

用法

Western blotting: 0.01-2µg/mL;
Immunohistochemistry: 5-20µg/mL;
Immunofluorescence:5-30µg/mL;
Optimal working dilutions must be determined by end user.

储存

经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。

稳定性

热稳定性以损失率显示。损失率是由加速降解试验决定,具体方法如下:在37°C孵育48小时,没有显著的降解或者沉淀产生。保质期内,在适当的条件下存储,损失率低于5%。

赠品

相关产品

编号适用物种:Homo sapiens (Human,人)应用(仅供研究使用,不用于临床诊断!)
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SEA979Hu亲环素A(CYPA)检测试剂盒(酶联免疫吸附试验法)Enzyme-linked immunosorbent assay for Antigen Detection.
LMA979Hu亲环素A(CYPA)等多因子检测试剂盒(流式荧光发光法)FLIA Kit for Antigen Detection.
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KSA979Hu01亲环素A(CYPA)检测试剂盒DIY材料(酶联免疫吸附试验法)Main materials for "Do It (ELISA Kit) Yourself".

参考文献

杂志参考文献
AtherosclerosisEMMPRIN and its ligand cyclophilin A regulate MT1-MMP, MMP-9 and M-CSF during foam cell formation[PubMed: 19758589]
BiomarkersCyclophilin-A: a novel biomarker for untreated male essential hypertension[Pubmed: 24164594]
Cardiovascular DiabetologyPlasma level of cyclophilin A is increased in patients with type 2 diabetes mellitus and suggests presence of vascular disease[Pubmed:24502618]
International Journal of Biological SciencesDecrease in Plasma Cyclophilin A Concentration at 1 Month after Myocardial Infarction Predicts Better Left Ventricular Performance and Synchronicity at 6 Months: A Pilot Study in Patients with ST Elevation Myocardial Infarction[Pubmed:25552928]
MedicineCyclophilin A in Ruptured Intracranial Aneurysm[PubMed: 26426668]
Mol Cell BiochemPPIA rs6850: A> G single-nucleotide polymorphism is associated with raised plasma cyclophilin A levels in patients with coronary artery disease[PubMed: 26702934]
Medicine (Baltimore)Urinary Cyclophilin A as a New Marker for Diabetic Nephropathy: A Cross-Sectional Analysis of Diabetes Mellitus[PubMed: 26496315]
International Journal of CardiologyCyclophilin A modulates bone marrow-derived CD117(+) cells and enhances ischemia-induced angiogenesisvia the SDF-1/CXCR4 axis.[Pubmed:27057951]
Clinica Chimica ActaNovel findings of secreted cyclophilin A in diabetic nephropathy and its association with renal protection of dipeptidyl peptidase 4 inhibitor[pubmed:27823952]
Cardiovascular DiabetologyCyclophilin A enhances macrophage differentiation and lipid uptake in high glucose conditions: a cellular mechanism for accelerated macro vascular disease in diabetes mellitus.[pubmed:27809851]
Clinical ScienceMetformin attenuates effects of cyclophilin A on macrophages, reduces lipid uptake and secretion of cytokines by repressing decreased AMPK activity[Pubmed:29382697]
Journal of Molecular HistologyCyclophilin a increases CD68 cell infiltration in rat experimental periodontitis[Pubmed:29318411]
Free Radical ResearchCyclophilin A and CD147 associate with progression of diabetic nephropathy[Pubmed: 30572748]
The Kaohsiung Journal of Medical SciencesAssociation of cyclophilin A level and pulse pressure in predicting recurrence of cerebral infarction[Pubmed: 31670477]
Cells.Cyclophilin A/EMMPRIN Axis Is Involved in Pro-Fibrotic Processes Associated with Thoracic Aortic Aneurysm of Marfan Syndrome Patients[Pubmed: 31936351]
JAMA NeurologyAPPENDIX A: Relationship between cyclophilin A levels and matrix metalloproteinase-9 activity in cerebrospinal fluid of cognitively normal apolipoprotein E4 carriers …[Pubmed: 24030206]
Menoufia Medical JournalUrinary podocalyxin and cyclophilin A: markers for early detection of type 2 diabetic nephropathy[]
ToxinsEvaluation of the Therapeutic Effects of Protocatechuic Aldehyde in Diabetic Nephropathy[34437430]
Cell Death & DiseaseProteomic analysis reveals USP7 as a novel regulator of palmitic acid-induced hepatocellular carcinoma cell death[Pubmed:35732625]