武汉云克隆科技股份有限公司

表皮调节素(EREG)多克隆抗体

Polyclonal Antibody to Epiregulin (EREG)

EPR; ER; Proepiregulin

  • 表皮调节素(EREG)多克隆抗体产品包装(模拟)
  • 表皮调节素(EREG)多克隆抗体产品包装(模拟)
  • 表皮调节素(EREG)多克隆抗体DAB staining on IHC-P;
    Sample: Human Placenta Tissue
    Primary Ab: 10µg/ml Rabbit Anti-Human EREG Antibody
    Control: Used PBS instead of primary antibody
    Second Ab: 2μg/ml HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
    (Catalog: SAA544Rb19)
  • PAB945Hu04.jpgWestern Blot; Sample: Porcine Tongue lysate Primary Ab: 0.05µg/ml Rabbit Anti-Human EREG Antibody Second Ab: 0.2μg/ml HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: SAA544Rb19)
  • Certificate通过ISO 9001、ISO 13485质量体系认证

特异性

该抗体是针对EREG的兔多克隆抗体。在免疫组织化学染色和免疫印迹实验中能识别EREG。

用法

免疫印迹：0.2-2µg/mL;1:250-2500
免疫组织化学：5-20µg/mL;1:25-100
免疫细胞化学：5-20µg/mL;1:25-100
最佳稀释倍数最终由用户决定。

储存

经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。

稳定性

热稳定性以损失率显示。损失率是由加速降解试验决定，具体方法如下：在37°C孵育48小时，没有显著的降解或者沉淀产生。保质期内，在适当的条件下存储，损失率低于5%。

赠品

相关产品

编号适用物种：Homo sapiens (Human，人)应用(仅供研究使用，不用于临床诊断！)
RPB945Hu02表皮调节素(EREG)重组蛋白Positive Control; Immunogen; SDS-PAGE; WB.
RPB945Hu04表皮调节素(EREG)重组蛋白Positive Control; Immunogen; SDS-PAGE; WB.
RPB945Hu01表皮调节素(EREG)重组蛋白Positive Control; Immunogen; SDS-PAGE; WB.
RPB945Hu03表皮调节素(EREG)重组蛋白Positive Control; Immunogen; SDS-PAGE; WB.
PAB945Hu02表皮调节素(EREG)多克隆抗体WB
PAB945Hu01表皮调节素(EREG)多克隆抗体WB
PAB945Hu04表皮调节素(EREG)多克隆抗体WB; IHC
MAB945Hu22表皮调节素(EREG)单克隆抗体WB; IHC; ICC; IP.
SEB945Hu表皮调节素(EREG)检测试剂盒(酶联免疫吸附试验法)Enzyme-linked immunosorbent assay for Antigen Detection.
SCB945Hu表皮调节素(EREG)检测试剂盒(化学发光免疫分析法)Chemiluminescent immunoassay for Antigen Detection.
LMB945Hu表皮调节素(EREG)等多因子检测试剂盒(流式荧光发光法)FLIA Kit for Antigen Detection.

参考文献

杂志参考文献
British Journal of CancerCross-suppression of EGFR ligands amphiregulin and epiregulin and de-repression of FGFR3 signalling contribute to cetuximab resistance in wild-type KRAS tumour cells[Nature: 2012103]
J Pharmacol Exp Ther. Aryl hydrocarbon receptor antagonism attenuates growth factor expression, proliferation, and migration in fibroblast-like synoviocytes from patients with rheumatoid arthritis.[Pubmed: 24309559]
Molecular CarcinogenesisThe Ah receptor regulates growth factor expression in head and neck squamous cell carcinoma cell lines[Pubmed:23625689]
Am J Physiol Gastrointest Liver Physiol. Epiregulin promotes the emergence and proliferation of adult liver progenitor cells.[Pubmed:24812054]
European Review for Medical and Pharmacological SciencesEpiregulin-loaded PLGA nanoparticles increase human keratinocytes proliferation: preliminary data[pubmed:27383296]
OncotargetOverexpression of a functional calcium-sensing receptor dramatically increases osteolytic potential of MDA-MB-231 cells in a mouse model of bone metastasis through epiregulin-mediated osteoprotegerin downregulation[PMC5593575]
American journal of respiratory cell and molecular biologyPotential Involvement of the Epidermal Growth Factor Receptor Ligand Epiregulin and Matrix Metalloproteinase-1 in Pathogenesis of Chronic Rhinosinusitis[pubmed:28398769]
International Journal of CancerEpigenetic regulation of Amphiregulin and Epiregulin in colorectal cancer[Pubmed: 30252132]
Epiregulin is released from intervertebral disks and induces spontaneous activity in pain pathways[Doi: 10.1097/PR9.0000000000000718]
Cell proliferationEpiregulin enhances odontoblastic differentiation of dental pulp stem cells via activating MAPK signalling pathway[Pubmed: 31454111]
International Journal of Molecular SciencesPromising Therapeutic Efficacy of GC1118, an Anti-EGFR Antibody, against KRAS Mutation-Driven Colorectal Cancer Patient-Derived Xenografts[Pubmed: 31771279]
NeoplasiaPatient-derived xenograft (PDX) models of colorectal carcinoma (CRC) as a platform for chemosensitivity and biomarker analysis in personalized medicine[Pubmed: 33212364]
Reprod SciCompromised Cumulus-Oocyte Complex Matrix Organization and Expansion in Women with PCOS[34748173]
Tissue and CellMiR-192-5p suppresses M1 macrophage polarization via epiregulin (EREG) downregulation in gouty arthritis[34715618]