组蛋白H4(H4)多克隆抗体
Polyclonal Antibody to Histone H4 (H4)
- 编号PAA289Mi02
- 物种Homo sapiens (Human，人), Mus musculus (Mouse，小鼠), Rattus norvegicus (Rat，大鼠), Cavia (Guinea pig ，豚鼠), Rhesus monkey (Simian，恒河猴), Felis catus; Feline (Cat，猫), Canis familiaris; Canine (Dog，犬), Sus scrofa; Porcine (Pig，猪), Bos taurus; Bovine (Cattle，牛), Equus caballus; Equine (Horse，马), Chicken (Gallus，鸡)相同的名称，不同的物种。
- 来源多抗制备
- 宿主兔
- 效价-
- Ig类型IgG
- 纯化方式抗原特异性亲和纯化
- 标记物无标记物
- 免疫原RPA289Mi02-组蛋白H4(H4)重组蛋白
- 缓冲液成份0.01M 磷酸盐缓冲液（pH7.4，containing 0.05% Proclin-300，50% glycerol）
- 性状液体
- 浓度0.5mg/ml
- 且适物种Mus musculus (Mouse，小鼠), Rattus norvegicus (Rat，大鼠), Oryctolagus cuniculus (Rabbit，兔)
- 应用WB; IHC; ICC; IP.
如果抗体需用于流式细胞术，请参见流式抗体。 - 下载英文说明书 中文说明书
- 规格20µl100µl200µl1ml10ml
- 价格¥ 583¥ 1361¥ 1944¥ 4860¥ 19440
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产品包装(模拟)
产品包装(模拟)
WB图
通过ISO 9001、ISO 13485质量体系认证
特异性
该抗体是针对H4的兔多克隆抗体。在免疫组织化学染色和免疫印迹实验中能识别H4。
用法
Western blotting: 0.5-2µg/mL;
Immunohistochemistry: 5-20µg/mL;
Immunocytochemistry: 5-20µg/mL;
Optimal working dilutions must be determined by end user.
储存
经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。
稳定性
热稳定性以损失率显示。损失率是由加速降解试验决定，具体方法如下：在37°C孵育48小时，没有显著的降解或者沉淀产生。保质期内，在适当的条件下存储，损失率低于5%。
赠品
相关产品
| 编号 | 适用物种：Homo sapiens (Human，人), Mus musculus (Mouse，小鼠), Rattus norvegicus (Rat，大鼠), Cavia (Guinea pig ，豚鼠), Rhesus monkey (Simian，恒河猴), Felis catus; Feline (Cat，猫), Canis familiaris; Canine (Dog，犬), Sus scrofa; Porcine (Pig，猪), Bos taurus; Bovine (Cattle，牛), Equus caballus; Equine (Horse，马), Chicken (Gallus，鸡) | 应用(仅供研究使用，不用于临床诊断！) |
| RPA289Mi02 | 组蛋白H4(H4)重组蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPA289Mi01 | 组蛋白H4(H4)重组蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| PAA289Mi02 | 组蛋白H4(H4)多克隆抗体 | WB; IHC; ICC; IP. |
| PAA289Mi01 | 组蛋白H4(H4)多克隆抗体 | WB; IHC; ICC; IP. |
| SEA289Mi | 组蛋白H4(H4)检测试剂盒(酶联免疫吸附试验法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| HEA289Mi | 组蛋白H4(H4)检测试剂盒(酶联免疫吸附试验法,高敏型) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| LMA289Mi | 组蛋白H4(H4)等多因子检测试剂盒(流式荧光发光法) | FLIA Kit for Antigen Detection. |
参考文献
| 杂志 | 参考文献 |
| PLoS One. | N-Acetyl-Heparin Attenuates Acute Lung Injury Caused by Acid Aspiration Mainly by Antagonizing Histones in Mice[Pubmed:24816808] |
| Crit Care. | Impact of plasma histones in human sepsis and their contribution to cellular injury and inflammation[Pubmed:25260379] |
| Biomed Res Int | A Novel Anti-Histone H2 Monoclonal Antibody, SSV Monoclonal Antibody, Improves Lung Injury and Survival in a Mouse Model of Lipopolysaccharide-Induced Sepsis-Like Syndrome[PubMed: 25649891] |
| Journal of Viral Hepatitis | Patients with HBV-related acute-on-chronic liver failure have increased concentrations of extracellular histones aggravating cellular damage and systemic inflammation[pubmed:27660136] |
| Cell Death & Disease | Dexmedetomidine inhibits astrocyte pyroptosis and subsequently protects the brain in in vitro and in vivo models of sepsis[Pubmed: 30778043] |
| Respir Res | Histone H4 induces heparan sulfate degradation by activating heparanase in chlorine gas-induced acute respiratory distress syndrome[Pubmed:35073921] |