RPA289Mi02 | 组蛋白H4(H4)重组蛋白 | Homo sapiens (Human，人), Mus musculus (Mouse，小鼠), Rattus norvegicus (Rat，大鼠), Cavia (Guinea pig ，豚鼠), Rhesus monkey (Simian，恒河猴), Felis catus; Feline (Cat，猫), Canis familiaris; Canine (Dog，犬), Sus scrofa; Porcine (Pig，猪), Bos taurus; Bovine (Cattle，牛), Equus caballus; Equine (Horse，马) USCN(武汉云克隆科技股份有限公司官方网站)

组蛋白H4(H4)重组蛋白

编号RPA289Mi02
物种Homo sapiens (Human，人), Mus musculus (Mouse，小鼠), Rattus norvegicus (Rat，大鼠), Cavia (Guinea pig ，豚鼠), Rhesus monkey (Simian，恒河猴), Felis catus; Feline (Cat，猫), Canis familiaris; Canine (Dog，犬), Sus scrofa; Porcine (Pig，猪), Bos taurus; Bovine (Cattle，牛), Equus caballus; Equine (Horse，马)相同的名称，不同的物种。
来源原核表达
宿主E.coli
内毒素水平<1.0EU/µg(LAL法测定)
亚细胞定位分泌, 染色体
预测分子量41.3kDa
实际分子量42kDa(差异分析请参阅说明书)
片段与标签Ser2~Gly103 with N-terminal His and GST Tag
缓冲液成份20mM Tris, 150mM NaCl缓冲液（pH8.0, 含有1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose和Proclin300）
性状冻干粉
纯度> 90%
等电点11.9
应用Positive Control; Immunogen; SDS-PAGE; WB.
如果需要有生物活性的蛋白，请参见活性蛋白。
下载英文说明书中文说明书
规格10µg50µg200µg1mg5mg
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Reconstitute in ddH₂O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

避免反复冻融。2-8°C不超过一个月，-80°C不超过12个月。

热稳定性以损失率显示。损失率是由加速降解试验决定，具体方法如下：在37°C孵育48小时，没有显著的降解或者沉淀产生。保质期内，在适当的条件下存储，损失率低于5%。

编号	适用物种：Homo sapiens (Human，人), Mus musculus (Mouse，小鼠), Rattus norvegicus (Rat，大鼠), Cavia (Guinea pig ，豚鼠), Rhesus monkey (Simian，恒河猴), Felis catus; Feline (Cat，猫), Canis familiaris; Canine (Dog，犬), Sus scrofa; Porcine (Pig，猪), Bos taurus; Bovine (Cattle，牛), Equus caballus; Equine (Horse，马)	应用(仅供研究使用，不用于临床诊断！)
RPA289Mi02	组蛋白H4(H4)重组蛋白	Positive Control; Immunogen; SDS-PAGE; WB.
RPA289Mi01	组蛋白H4(H4)重组蛋白	Positive Control; Immunogen; SDS-PAGE; WB.
PAA289Mi02	组蛋白H4(H4)多克隆抗体	WB; IHC; ICC; IP.
PAA289Mi01	组蛋白H4(H4)多克隆抗体	WB; IHC; ICC; IP.
SEA289Mi	组蛋白H4(H4)检测试剂盒(酶联免疫吸附试验法)	Enzyme-linked immunosorbent assay for Antigen Detection.
HEA289Mi	组蛋白H4(H4)检测试剂盒(酶联免疫吸附试验法,高敏型)	Enzyme-linked immunosorbent assay for Antigen Detection.
LMA289Mi	组蛋白H4(H4)等多因子检测试剂盒(流式荧光发光法)	FLIA Kit for Antigen Detection.

杂志	参考文献
PLoS One.	N-Acetyl-Heparin Attenuates Acute Lung Injury Caused by Acid Aspiration Mainly by Antagonizing Histones in Mice[Pubmed:24816808]
Crit Care.	Impact of plasma histones in human sepsis and their contribution to cellular injury and inflammation[Pubmed:25260379]
Biomed Res Int	A Novel Anti-Histone H2 Monoclonal Antibody, SSV Monoclonal Antibody, Improves Lung Injury and Survival in a Mouse Model of Lipopolysaccharide-Induced Sepsis-Like Syndrome[PubMed: 25649891]
Journal of Viral Hepatitis	Patients with HBV-related acute-on-chronic liver failure have increased concentrations of extracellular histones aggravating cellular damage and systemic inflammation[pubmed:27660136]
Cell Death & Disease	Dexmedetomidine inhibits astrocyte pyroptosis and subsequently protects the brain in in vitro and in vivo models of sepsis[Pubmed: 30778043]
Respir Res	Histone H4 induces heparan sulfate degradation by activating heparanase in chlorine gas-induced acute respiratory distress syndrome[Pubmed:35073921]